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Protein
Submitted name:

Prune homolog 2

Gene

PRUNE2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Prune homolog 2Imported
Gene namesi
Name:PRUNE2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

PTM / Processingi

Proteomic databases

PeptideAtlasiD6RTK6
PRIDEiD6RTK6

PTM databases

iPTMnetiD6RTK6

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2895 – 3059CRAL-TRIOInterPro annotationAdd BLAST165

Phylogenomic databases

eggNOGiENOG410IFIP Eukaryota
ENOG410ZS9Z LUCA

Family and domain databases

CDDicd00170 SEC14, 1 hit
Gene3Di3.40.525.10, 1 hit
InterProiView protein in InterPro
IPR022181 Bcl2-/adenovirus-E1B
IPR001251 CRAL-TRIO_dom
IPR036865 CRAL-TRIO_dom_sf
IPR038763 DHH_sf
IPR004097 DHHA2
PfamiView protein in Pfam
PF12496 BNIP2, 1 hit
PF13716 CRAL_TRIO_2, 1 hit
PF02833 DHHA2, 1 hit
SMARTiView protein in SMART
SM01131 DHHA2, 1 hit
SM00516 SEC14, 1 hit
SUPFAMiSSF52087 SSF52087, 1 hit
SSF64182 SSF64182, 1 hit
PROSITEiView protein in PROSITE
PS50191 CRAL_TRIO, 1 hit

Sequencei

Sequence statusi: Complete.

D6RTK6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEEFLQRAKS KLNRSKRLEK VHVVIGPKSC DLDSLISTFT YAYFLDKVSP
60 70 80 90 100
PGVLCLPVLN IPRTEFNYFT ETRFILEELN ISESFHIFRD EINLHQLNDE
110 120 130 140 150
GKLSITLVGS SVLASEDKTL ESAVVKVINP VEQSDANVEF RESSSSLVLK
160 170 180 190 200
EILQEAPELI TEQLAHRLRG SILFKWMTME SEKISEKQEE ILSILEEKFP
210 220 230 240 250
NLPPREDIIN VLQETQFSAQ GLSIEQTMLK DLKELSDGEI KVAISTVSMN
260 270 280 290 300
LENCLFHSNI TSDLKAFTDK FGFDVLILFS SYLSEEQQPR RQIAVYSENM
310 320 330 340 350
ELCSQICCEL EECQNPCLEL EPFDCGCDEI LVYQQEDPSV TCDQVVLVVK
360 370 380 390 400
EVINRRCPEM VSNSRTSSTE AVAGSAPLSQ GSSGIMELYG SDIEPQPSSV
410 420 430 440 450
NFIENPPDLN DSNQAQVDAN VDLVSPDSGL ATIRSSRSSK ESSVFLSDDS
460 470 480 490 500
PVGEGAGPHH TLLPGLDSYS PIPEGAVAEE HAWSGEHGEH FDLFNFDPAP
510 520 530 540 550
MASGQSQQSS HSADYSPADD FFPNSDLSEG QLPAGPEGLD GMGTNMSNYS
560 570 580 590 600
SSSLLSGAGK DSLVEHDEEF VQRQDSPRDN SERNLSLTDF VGDESPSPER
610 620 630 640 650
LKNTGKRIPP TPMNSLVESS PSTEEPASLY TEDMTQKATD TGHMGPPQTH
660 670 680 690 700
ARCSSWWGGL EIDSKNIADA WSSSEQESVF QSPESWKEHK PSSIDRRASD
710 720 730 740 750
SVFQPKSLEF TKSGPWESEF GQPELGSNDI QDKNEESLPF QNLPMEKSPL
760 770 780 790 800
PNTSPQGTNH LIEDFASLWH SGRSPTAMPE PWGNPTDDGE PAAVAPFPAW
810 820 830 840 850
SAFGKEDHDE ALKNTWDLHP TSSKTPSVRD PNEWAMAKSG FAFSSSELLD
860 870 880 890 900
NSPSEINNEA APEIWGKKNN DSRDHIFAPG NPSSDLDHTW TNSKPPKEDQ
910 920 930 940 950
NGLVDPKTRG KVYEKVDSWN LFEENMKKGG SDVLVPWEDS FLSYKCSDYS
960 970 980 990 1000
ASNLGEDSVP SPLDTNYSTS DSYTSPTFAG DEKETEHKPF AKEEGFESKD
1010 1020 1030 1040 1050
GNSMAEETDI PPQSLQQSLQ QSSRNRISSG PGNLDMWASP HTDNSSEINT
1060 1070 1080 1090 1100
THNLDENELK TEHTDGKNIS MEDDVGESSQ SSYDDPSMMQ LYNETNRQLT
1110 1120 1130 1140 1150
LLHSSTNSRQ TAPDSLDLWN RVILEDTQST ATISDMDNDL DWDDCSGGAA
1160 1170 1180 1190 1200
IPSDGQTEGY MAEGSEPETR FTVRQLEPWG LEYQEANQVD WELPASDEHT
1210 1220 1230 1240 1250
KDSAPSEHHT LNEKSGQLIA NSIWDSVMRD KDMSSFMLPG SSHITDSEQR
1260 1270 1280 1290 1300
ELPPEIPSHS ANVKDTHSPD APAASGTSES EALISHLDKQ DTERETLQSD
1310 1320 1330 1340 1350
AASLATRLEN PGYFPHPDPW KGHGDGQSES EKEAQGATDR GHLDEEEVIA
1360 1370 1380 1390 1400
SGVENASGIS EKGQSDQELS SLVASEHQEI CIKSGKISSL AVTFSPQTEE
1410 1420 1430 1440 1450
PEEVLEYEEG SYNLDSRDVQ TGMSADNLQP KDTHEKHLMS QRNSGETTET
1460 1470 1480 1490 1500
SDGMNFTKYV SVPEKDLEKT EECNFLEPEN VGGGPPHRVP RSLDFGDVPI
1510 1520 1530 1540 1550
DSDVHVSSTR SEITKNLDVK GSENSLPGAG SSGNFDRDTI SSEYTHSSAS
1560 1570 1580 1590 1600
SPELNDSSVA LSSWGQQPSS GYQEENQGNW SEQNHQESEL ITTDGQVEIV
1610 1620 1630 1640 1650
TKVKDLEKNR INEFEKSFDR KTPTFLEIWN DSVDGDSFSS LSSPETGKYS
1660 1670 1680 1690 1700
EHSGTHQESN LIASYQEKNE HDISATVQPE DARVISTSSG SDDDSVGGEE
1710 1720 1730 1740 1750
SIEEEIQVAN CNVAEDESRA WDSLNESNKF LVTADPKSEN IYDYLDSSEP
1760 1770 1780 1790 1800
AENENKSNPF CDNQQSSPDP WTFSPLTETE MQITAVEKEK RSSPETGTTG
1810 1820 1830 1840 1850
DVAWQISPKA SFPKNEDNSQ LEMLGFSADS TEWWKASPQE GRLIESPFER
1860 1870 1880 1890 1900
ELSDSSGVLE INSSVHQNAS PWGVPVQGDI EPVETHYTNP FSDNHQSPFL
1910 1920 1930 1940 1950
EGNGKNSHEQ LWNIQPRQPD PDADKFSQLV KLDQIKEKDS REQTFVSAAG
1960 1970 1980 1990 2000
DELTPETPTQ EQCQDTMLPV CDHPDAAFTH AEENSCVTSN VSTNEGQETN
2010 2020 2030 2040 2050
QWEQEKSYLG EMTNSSIATE NFPAVSSPTQ LIMKPGSEWD GSTPSEDSRG
2060 2070 2080 2090 2100
TFVPDILHGN FQEGGQLASA APDLWIDAKK PFSLKADGEN PDILTHCEHD
2110 2120 2130 2140 2150
SNSQASDSPD ICHDSEAKQE TEKHLSACMG PEVESSELCL TEPEIDEEPI
2160 2170 2180 2190 2200
YEPGREFVPS NAELDSENAT VLPPIGYQAD IKGSSQPTSH KGSPEPSEIN
2210 2220 2230 2240 2250
GDNSTGLQVS EKGASPDMAP ILEPVDRRIP RIENVATSIF VTHQEPTPEG
2260 2270 2280 2290 2300
DGSWISDSFS PESQPGARAL FDGDPHLSTE NPALVPDALL ASDTCLDISE
2310 2320 2330 2340 2350
AAFDHSFSDA SGLNTSTGTI DDMSKLTLSE GHPETPVDGD LGKQDICSSE
2360 2370 2380 2390 2400
ASWGDFEYDV MGQNIDEDLL REPEHFLYGG DPPLEEDSLK QSLAPYTPPF
2410 2420 2430 2440 2450
DLSYLTEPAQ SAETIEEAGS PEDESLGCRA AEIVLSALPD RRSEGNQAET
2460 2470 2480 2490 2500
KNRLPGSQLA VLHIREDPES VYLPVGAGSN ILSPSNVDWE VETDNSDLPA
2510 2520 2530 2540 2550
GGDIGPPNGA SKEIPELEEE KTIPTKEPEQ IKSEYKEERC TEKNEDRHAL
2560 2570 2580 2590 2600
HMDYILVNRE ENSHSKPETC EERESIAELE LYVGSKETGL QGTQLASFPD
2610 2620 2630 2640 2650
TCQPASLNER KGLSAEKMSS KGDTRSSFES PAQDQSWMFL GHSEVGDPSL
2660 2670 2680 2690 2700
DARDSGPGWS GKTVEPFSEL GLGEGPQLQI LEEMKPLESL ALEEASGPVS
2710 2720 2730 2740 2750
QSQKSKSRGR AGPDAVTHDN EWEMLSPQPV QKNMIPDTEM EEETEFLELG
2760 2770 2780 2790 2800
TRISRPNGLL SEDVGMDIPF EEGVLSPSAA DMRPEPPNSL DLNDTHPRRI
2810 2820 2830 2840 2850
KLTAPNINLS LDQSEGSILS DDNLDSPDEI DINVDELDTP DEADSFEYTG
2860 2870 2880 2890 2900
HEDPTANKDS GQESESIPEY TAEEEREDNR LWRTVVIGEQ EQRIDMKVIE
2910 2920 2930 2940 2950
PYRRVISHGG DSGYYGDGLN AIIVFAACFL PDSSRADYHY VMENLFLYVI
2960 2970 2980 2990 3000
STLELMVAED YMIVYLNGAT PRRRMPGLGW MKKCYQMIDR RLRKNLKSFI
3010 3020 3030 3040 3050
IVHPSWFIRT ILAVTRPFIS SKFSSKIKYV NSLSELSGLI PMDCIHIPES
3060
IINIDLKLKE KP
Length:3,062
Mass (Da):337,720
Last modified:August 10, 2010 - v1
Checksum:i0E5EA5E7F566C452
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB535152 mRNA Translation: BAJ08045.1
RefSeqiNP_001294976.1, NM_001308047.1
NP_001294977.1, NM_001308048.1
UniGeneiHs.262857

Genome annotation databases

GeneIDi158471

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB535152 mRNA Translation: BAJ08045.1
RefSeqiNP_001294976.1, NM_001308047.1
NP_001294977.1, NM_001308048.1
UniGeneiHs.262857

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiD6RTK6

Proteomic databases

PeptideAtlasiD6RTK6
PRIDEiD6RTK6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi158471

Organism-specific databases

CTDi158471

Phylogenomic databases

eggNOGiENOG410IFIP Eukaryota
ENOG410ZS9Z LUCA

Miscellaneous databases

ChiTaRSiPRUNE2 human
GenomeRNAii158471

Family and domain databases

CDDicd00170 SEC14, 1 hit
Gene3Di3.40.525.10, 1 hit
InterProiView protein in InterPro
IPR022181 Bcl2-/adenovirus-E1B
IPR001251 CRAL-TRIO_dom
IPR036865 CRAL-TRIO_dom_sf
IPR038763 DHH_sf
IPR004097 DHHA2
PfamiView protein in Pfam
PF12496 BNIP2, 1 hit
PF13716 CRAL_TRIO_2, 1 hit
PF02833 DHHA2, 1 hit
SMARTiView protein in SMART
SM01131 DHHA2, 1 hit
SM00516 SEC14, 1 hit
SUPFAMiSSF52087 SSF52087, 1 hit
SSF64182 SSF64182, 1 hit
PROSITEiView protein in PROSITE
PS50191 CRAL_TRIO, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD6RTK6_HUMAN
AccessioniPrimary (citable) accession number: D6RTK6
Entry historyiIntegrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: May 23, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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