UniProtKB - D6RJB7 (D6RJB7_HUMAN)
Protein
Submitted name:
Ankyrin repeat domain-containing protein 31
Gene
ANKRD31
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Ankyrin repeat domain-containing protein 31Imported |
Gene namesi | Name:ANKRD31Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000145700.9 |
HGNCi | HGNC:26853, ANKRD31 |
Expressioni
Gene expression databases
Bgeei | ENSG00000145700, Expressed in testis and 58 other tissues |
ExpressionAtlasi | D6RJB7, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 488 – 595 | ANK_REP_REGIONInterPro annotationAdd BLAST | 108 | |
Repeati | 521 – 553 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 554 – 586 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Domaini | 1205 – 1318 | ANK_REP_REGIONInterPro annotationAdd BLAST | 114 | |
Repeati | 1211 – 1243 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 1244 – 1276 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 1277 – 1309 | ANKPROSITE-ProRule annotationAdd BLAST | 33 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 27 | DisorderedSequence analysisAdd BLAST | 27 | |
Regioni | 361 – 380 | DisorderedSequence analysisAdd BLAST | 20 | |
Regioni | 707 – 740 | DisorderedSequence analysisAdd BLAST | 34 | |
Regioni | 1299 – 1320 | DisorderedSequence analysisAdd BLAST | 22 | |
Regioni | 1506 – 1539 | DisorderedSequence analysisAdd BLAST | 34 | |
Regioni | 1569 – 1628 | DisorderedSequence analysisAdd BLAST | 60 | |
Regioni | 1663 – 1691 | DisorderedSequence analysisAdd BLAST | 29 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1506 – 1520 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 1521 – 1539 | PolarSequence analysisAdd BLAST | 19 | |
Compositional biasi | 1571 – 1585 | PolarSequence analysisAdd BLAST | 15 | |
Compositional biasi | 1674 – 1691 | PolarSequence analysisAdd BLAST | 18 |
Keywords - Domaini
ANK repeatPROSITE-ProRule annotationARBA annotation, RepeatARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000162618 |
OMAi | TESEIHM |
OrthoDBi | 51193at2759 |
Family and domain databases
Gene3Di | 1.25.40.20, 2 hits |
InterProi | View protein in InterPro IPR042334, ANKRD31 IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf IPR040843, RAMA |
PANTHERi | PTHR24176, PTHR24176, 3 hits |
Pfami | View protein in Pfam PF00023, Ank, 2 hits PF12796, Ank_2, 1 hit PF18755, RAMA, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 6 hits |
SUPFAMi | SSF48403, SSF48403, 2 hits |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 2 hits PS50088, ANK_REPEAT, 5 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
D6RJB7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEEGVQAPDW DSDETVIEGS VTESDLEEKE LPWRRLLFDQ DASLKSEFSL
60 70 80 90 100
HPDTRGMCKG MPSPEIQLGF KLREDLQEQM NKNKMMPVLS EDTILQSQDE
110 120 130 140 150
TERNQALLQT RKNCSMFIGS FRQSGLSLNH QNIEGPEAES PEVLPHIEKE
160 170 180 190 200
LSEGRDSPEV SLLSGTAITV SDTVAVKETS LVEPEKILAA PNTFFEPRKE
210 220 230 240 250
VTMTMTSEET KDEESSLETF VSALESLLTS PESTQEERLF ELVSDFDRKE
260 270 280 290 300
LMNPLSDSLS SISIPLNSWS ACHRDLLEDA KDDALPAELL EALNTLSEAK
310 320 330 340 350
VETICHRKEG GSSLIARNEC LEVEFNTSQT NEDCTQIAET LQDPNPSGLQ
360 370 380 390 400
TLAHQNITSC EPLSNKRNSN SVTNSSDQET ACVLRRSSRL EKLKVSRDAK
410 420 430 440 450
YSDHMYKMPE KILPKILGCE DLTNNNSSAQ NFRMQDPALM IDGKEKNMHS
460 470 480 490 500
ARFKNGKQIR KNEQFSGKKE KMKVNKISLH SINRRNIFGE NLVYKAALHD
510 520 530 540 550
DADLVHHCIK KGGNVNQPSY AGWTALHEAS VGGFYRTASE LLKGGADVNI
560 570 580 590 600
KGLYQITPLH DAVMNGHYKV AELLLLNGAD PLFRNDDGKC ALDEAKDLCM
610 620 630 640 650
KRLLERYIPK HQKCLTSAQR SSIDPLDIED VYQHKKPKFS SKSHIWHVYN
660 670 680 690 700
ENSNRQKLEH VKVNKGSKAS LFINKEDVYE YYQKDPKNTK FGKSKHKQST
710 720 730 740 750
LDQIYSTGLR KGNLHNVKDP NTNVPKGIGR RKTQHKRTQV DDVDCNPRKI
760 770 780 790 800
LAVSPSRRIN RLVTYQQHIP ETHNDLPEEL CEPSSLTLSS LRNGLDSSTE
810 820 830 840 850
ACSVSKEKHI QNLDLSDSQE VQCLELESVD QTEAVSFPGL LLHKEIKLPV
860 870 880 890 900
VTTDKQPHTL QEQHHVLYKS HENSNLVPKD ERFNKWENSF LSFVKENSDN
910 920 930 940 950
DDDDDCSTSE KAITSKKVLC STGGKKHYNF KENLTNKKEM GFQQFLLSED
960 970 980 990 1000
HLSQENELKA VSLTTLPEQE AVNFSYSDNA VISEHVANYE QCIFGPSFDH
1010 1020 1030 1040 1050
SNGNPEQNSL ACMRTLLTHE ASKLTNHVEL FKKPQDYIPR APTFLMNQTD
1060 1070 1080 1090 1100
THIVEKMAKN CDTERNYIDR DQKIIYSNEP LSIVAHSQVI ETTKVEKRRQ
1110 1120 1130 1140 1150
NHLESETIHN IDSHSTDNMS KELANISKLS QREKKEISHK PDEELTNNIS
1160 1170 1180 1190 1200
GDEITIRNCE EIKEKTESEI HMPTNSQEHK TVQNFRKRQS FLKTTCNLGM
1210 1220 1230 1240 1250
KAGRINKRNA RGESQLHLAV RRGNLPLVKA LIESGADVNL NDNAGWTPLH
1260 1270 1280 1290 1300
EASNEGSIDI IVELLKAGAK VNCENIDGIL PLHDAVANNH LKAAEILLQN
1310 1320 1330 1340 1350
GANPNQKDQK QKSALDEADD EKMKELLRSY GAIETVNRDE SDAIVNEKIP
1360 1370 1380 1390 1400
AVRSKRHKQC FCDDGKTIDS SSLSHQERSR ESLSVHQTLS AILQDIEEKQ
1410 1420 1430 1440 1450
EYLLEFEIRN PEDAEQYIEK MLKIKKIMDN VLAKQKAERD DLAKKYRVSI
1460 1470 1480 1490 1500
ESFKHGALRE QLANLAARQK SLLVVAKKQK KISLKIQNCR NVTSLPCLSL
1510 1520 1530 1540 1550
RKLPPRSEIS SEKDSQELTS LENLEHPQSG SLSPVSGSMQ ETQLSLETWN
1560 1570 1580 1590 1600
YSQNTNICLN SEAVRRGEFS GNDMNSKQNG SDCTLDGFPK SRHSDGTEKN
1610 1620 1630 1640 1650
KLPSQPVAFI GQTEYSQKEN DLTEATDKDH EFYVSSPVIG KLNISETASV
1660 1670 1680 1690 1700
LAENAAHPSN IICDQDLSNY DPKRGNRKTS SQQSPTGASE SLAHQGIAVL
1710 1720 1730 1740 1750
GSDTVHQMKP YLKKSVSVVP CADDSQISSS SGSGQQDTIK KALNYSTAPK
1760 1770 1780 1790 1800
KKCIQIKDLI LLGRINPGNN ILEFKTQETT HKASILLNGK LKVESGQIYK
1810 1820 1830 1840 1850
NPVTWLKDLL GGNSYVTWNY AWSKVTYLGK ELLRYVSEDA PILPEPNSVP
1860 1870 1880 1890 1900
QQYQPCLPEV ACLDDPVQEP NKSMFEKTKF GQGTSRESMQ SSPRYLQINE
1910 1920 1930
ILLISDQEFL PCHIMDQHWK FCVECEELTP
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8N7Z5 | ANR31_HUMAN | Ankyrin repeat domain-containing pr... | ANKRD31 | 1,873 | Annotation score: | ||
A0A669KAY2 | A0A669KAY2_HUMAN | Ankyrin repeat domain-containing pr... | ANKRD31 | 35 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC008769 Genomic DNA No translation available. AC093259 Genomic DNA No translation available. |
RefSeqi | XP_011541601.1, XM_011543299.1 |
Genome annotation databases
Ensembli | ENST00000506364; ENSP00000427262; ENSG00000145700 |
UCSCi | uc063epm.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC008769 Genomic DNA No translation available. AC093259 Genomic DNA No translation available. |
RefSeqi | XP_011541601.1, XM_011543299.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | D6RJB7 |
PRIDEi | D6RJB7 |
ProteomicsDBi | 15099 |
Protocols and materials databases
Antibodypediai | 48719, 5 antibodies |
Genome annotation databases
Ensembli | ENST00000506364; ENSP00000427262; ENSG00000145700 |
UCSCi | uc063epm.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000145700.9 |
HGNCi | HGNC:26853, ANKRD31 |
OpenTargetsi | ENSG00000145700 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000162618 |
OMAi | TESEIHM |
OrthoDBi | 51193at2759 |
Miscellaneous databases
BioGRID-ORCSi | 256006, 7 hits in 768 CRISPR screens |
ChiTaRSi | ANKRD31, human |
GenomeRNAii | 256006 |
Gene expression databases
Bgeei | ENSG00000145700, Expressed in testis and 58 other tissues |
ExpressionAtlasi | D6RJB7, baseline and differential |
Family and domain databases
Gene3Di | 1.25.40.20, 2 hits |
InterProi | View protein in InterPro IPR042334, ANKRD31 IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf IPR040843, RAMA |
PANTHERi | PTHR24176, PTHR24176, 3 hits |
Pfami | View protein in Pfam PF00023, Ank, 2 hits PF12796, Ank_2, 1 hit PF18755, RAMA, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 6 hits |
SUPFAMi | SSF48403, SSF48403, 2 hits |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 2 hits PS50088, ANK_REPEAT, 5 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D6RJB7_HUMAN | |
Accessioni | D6RJB7Primary (citable) accession number: D6RJB7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 13, 2010 |
Last sequence update: | February 19, 2014 | |
Last modified: | December 2, 2020 | |
This is version 73 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |