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Protein
Submitted name:

Eukaryotic translation initiation factor 4E type 1B

Gene

EIF4E1B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Eukaryotic translation initiation factor 4E type 1BImported
Gene namesi
Name:EIF4E1BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000175766.11
HGNCiHGNC:33179 EIF4E1B

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000175766

PTM / Processingi

Proteomic databases

MaxQBiD6RHE2
PeptideAtlasiD6RHE2
PRIDEiD6RHE2

Expressioni

Gene expression databases

BgeeiENSG00000175766 Expressed in 38 organ(s), highest expression level in prefrontal cortex
ExpressionAtlasiD6RHE2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD6RHE2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili6 – 26Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1670 Eukaryota
COG5053 LUCA
GeneTreeiENSGT00520000055549
HOGENOMiHOG000186751

Family and domain databases

Gene3Di3.30.760.10, 1 hit
InterProiView protein in InterPro
IPR023398 TIF_eIF4e-like
IPR001040 TIF_eIF_4E
PANTHERiPTHR11960 PTHR11960, 1 hit
SUPFAMiSSF55418 SSF55418, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

D6RHE2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLAVEVSEAE GGIREWEEEE KEEEAAERTP TGEKSPNSPR TLLSLRGKAR
60 70 80 90
TGGPMEVKLE LHPLQNRWAL WFFKNDRSRA WQDNLHLVTK
Length:90
Mass (Da):10,400
Last modified:July 13, 2010 - v1
Checksum:i9B9651DCBD71262F
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A6NMX2I4E1B_HUMAN
Eukaryotic translation initiation f...
EIF4E1B
242Annotation score:
H0Y8X3H0Y8X3_HUMAN
Eukaryotic translation initiation f...
EIF4E1B
171Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei90Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091934 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000510660; ENSP00000421009; ENSG00000175766
UCSCiuc063jzr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091934 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliD6RHE2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiD6RHE2
PeptideAtlasiD6RHE2
PRIDEiD6RHE2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000510660; ENSP00000421009; ENSG00000175766
UCSCiuc063jzr.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000175766.11
HGNCiHGNC:33179 EIF4E1B
OpenTargetsiENSG00000175766
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1670 Eukaryota
COG5053 LUCA
GeneTreeiENSGT00520000055549
HOGENOMiHOG000186751

Gene expression databases

BgeeiENSG00000175766 Expressed in 38 organ(s), highest expression level in prefrontal cortex
ExpressionAtlasiD6RHE2 baseline and differential

Family and domain databases

Gene3Di3.30.760.10, 1 hit
InterProiView protein in InterPro
IPR023398 TIF_eIF4e-like
IPR001040 TIF_eIF_4E
PANTHERiPTHR11960 PTHR11960, 1 hit
SUPFAMiSSF55418 SSF55418, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD6RHE2_HUMAN
AccessioniPrimary (citable) accession number: D6RHE2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: September 12, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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