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UniProtKB - D6RGY8 (D6RGY8_HUMAN)
Protein
Protein YIPF3
Gene
YIPF3
Organism
Homo sapiens (Human)
Status
Functioni
Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
ARBA annotationGO - Biological processi
- cell differentiation Source: UniProtKB-KW
Keywordsi
Biological process | DifferentiationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Protein YIPF3ARBA annotationAlternative name(s): YIP1 family member 3ARBA annotation |
Gene namesi | Name:YIPF3 |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:21023, YIPF3 |
VEuPathDBi | HostDB:ENSG00000137207 |
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm ARBA annotation
Golgi apparatus
- cis-Golgi network membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma membrane
- Cell membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Golgi apparatus
- Golgi apparatus Source: UniProtKB-SubCell
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Keywords - Cellular componenti
Cell membraneARBA annotation, CytoplasmARBA annotation, Golgi apparatusARBA annotation, MembranePTM / Processingi
Keywords - PTMi
GlycoproteinARBA annotationProteomic databases
MaxQBi | D6RGY8 |
PeptideAtlasi | D6RGY8 |
PRIDEi | D6RGY8 |
ProteomicsDBi | 14761 |
Expressioni
Gene expression databases
Bgeei | ENSG00000137207, Expressed in pancreas and 222 other tissues |
ExpressionAtlasi | D6RGY8, baseline and differential |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 44 | DisorderedSequence analysisAdd BLAST | 44 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 16 – 30 | Basic and acidic residuesSequence analysisAdd BLAST | 15 |
Sequence similaritiesi
Belongs to the YIP1 family.ARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000153766 |
HOGENOMi | CLU_1943052_0_0_1 |
OMAi | HCIVLFV |
Family and domain databases
InterProi | View protein in InterPro IPR026637, YIPF3 |
PANTHERi | PTHR15627:SF14, PTHR15627:SF14, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
D6RGY8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MENMDDTSGS SFEDMGELHQ RLREEEVDAD AADAAAAEEE DGEFLGMKGF
60 70 80 90 100
KGQLSRQVAD QMWQAGKRQA SRAFSLYANI DILRPYFDVE PAQVRSRLLE
SMIPIKMVN
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9GZM5 | YIPF3_HUMAN | Protein YIPF3 | YIPF3 C6orf109, KLIP1 | 350 | Annotation score: | ||
E7EQR8 | E7EQR8_HUMAN | Protein YIPF3 | YIPF3 | 356 | Annotation score: | ||
D6RFI3 | D6RFI3_HUMAN | Protein YIPF3 | YIPF3 | 262 | Annotation score: | ||
H0Y9A1 | H0Y9A1_HUMAN | Protein YIPF3 | YIPF3 | 135 | Annotation score: | ||
D6RAY4 | D6RAY4_HUMAN | Protein YIPF3 | YIPF3 | 64 | Annotation score: | ||
D6RA04 | D6RA04_HUMAN | Protein YIPF3 | YIPF3 | 63 | Annotation score: | ||
D6RBQ1 | D6RBQ1_HUMAN | Protein YIPF3 | YIPF3 | 45 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 109 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL355802 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000511831.1; ENSP00000421094.1; ENSG00000137207.12 |
UCSCi | uc063osr.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL355802 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | D6RGY8, 1 interactor |
Proteomic databases
MaxQBi | D6RGY8 |
PeptideAtlasi | D6RGY8 |
PRIDEi | D6RGY8 |
ProteomicsDBi | 14761 |
Protocols and materials databases
Antibodypediai | 3101, 118 antibodies from 23 providers |
Genome annotation databases
Ensembli | ENST00000511831.1; ENSP00000421094.1; ENSG00000137207.12 |
UCSCi | uc063osr.1, human |
Organism-specific databases
HGNCi | HGNC:21023, YIPF3 |
OpenTargetsi | ENSG00000137207 |
VEuPathDBi | HostDB:ENSG00000137207 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000153766 |
HOGENOMi | CLU_1943052_0_0_1 |
OMAi | HCIVLFV |
Miscellaneous databases
ChiTaRSi | YIPF3, human |
Gene expression databases
Bgeei | ENSG00000137207, Expressed in pancreas and 222 other tissues |
ExpressionAtlasi | D6RGY8, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR026637, YIPF3 |
PANTHERi | PTHR15627:SF14, PTHR15627:SF14, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | D6RGY8_HUMAN | |
Accessioni | D6RGY8Primary (citable) accession number: D6RGY8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 13, 2010 |
Last sequence update: | July 13, 2010 | |
Last modified: | May 25, 2022 | |
This is version 64 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |