UniProtKB - D6RFM7 (D6RFM7_HUMAN)
Protein
Submitted name:
Anaphase-promoting complex subunit 4
Gene
ANAPC4
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- anaphase-promoting complex-dependent catabolic process Source: InterPro
- cell cycle Source: UniProtKB-KW
- cell division Source: UniProtKB-KW
- regulation of mitotic metaphase/anaphase transition Source: InterPro
Keywordsi
Biological process | Cell cycle, Cell division, MitosisARBA annotation, Ubl conjugation pathwayARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Anaphase-promoting complex subunit 4Imported |
Gene namesi | Name:ANAPC4Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:19990, ANAPC4 |
VEuPathDBi | HostDB:ENSG00000053900.10 |
Subcellular locationi
Nucleus
- anaphase-promoting complex Source: InterPro
PTM / Processingi
Proteomic databases
MaxQBi | D6RFM7 |
PeptideAtlasi | D6RFM7 |
PRIDEi | D6RFM7 |
ProteomicsDBi | 14580 |
Expressioni
Gene expression databases
Bgeei | ENSG00000053900, Expressed in endometrium and 219 other tissues |
ExpressionAtlasi | D6RFM7, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 27 – 64 | ANAPC4_WD40InterPro annotationAdd BLAST | 38 |
Phylogenomic databases
GeneTreei | ENSGT00390000004612 |
HOGENOMi | CLU_2557705_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR024789, APC4 IPR024977, Apc4_WD40_dom |
PANTHERi | PTHR13260, PTHR13260, 1 hit |
Pfami | View protein in Pfam PF12894, ANAPC4_WD40, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
D6RFM7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLRFPTCFPS FRVVGEKQLP QEIIFLVWSP KRDLIALANT AGEVLLHRLA
60 70 80
SFHRVWSFPP NENTGKEFWP LLLLIPRKLF CVM
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9UJX5 | APC4_HUMAN | Anaphase-promoting complex subunit ... | ANAPC4 APC4 | 808 | Annotation score: | ||
D6RAP6 | D6RAP6_HUMAN | Anaphase-promoting complex subunit ... | ANAPC4 | 162 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC108218 Genomic DNA No translation available. AC110812 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000505080; ENSP00000426512; ENSG00000053900 |
UCSCi | uc062vre.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC108218 Genomic DNA No translation available. AC110812 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | D6RFM7 |
PeptideAtlasi | D6RFM7 |
PRIDEi | D6RFM7 |
ProteomicsDBi | 14580 |
Genome annotation databases
Ensembli | ENST00000505080; ENSP00000426512; ENSG00000053900 |
UCSCi | uc062vre.1, human |
Organism-specific databases
HGNCi | HGNC:19990, ANAPC4 |
OpenTargetsi | ENSG00000053900 |
VEuPathDBi | HostDB:ENSG00000053900.10 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000004612 |
HOGENOMi | CLU_2557705_0_0_1 |
Miscellaneous databases
ChiTaRSi | ANAPC4, human |
Gene expression databases
Bgeei | ENSG00000053900, Expressed in endometrium and 219 other tissues |
ExpressionAtlasi | D6RFM7, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR024789, APC4 IPR024977, Apc4_WD40_dom |
PANTHERi | PTHR13260, PTHR13260, 1 hit |
Pfami | View protein in Pfam PF12894, ANAPC4_WD40, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D6RFM7_HUMAN | |
Accessioni | D6RFM7Primary (citable) accession number: D6RFM7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 13, 2010 |
Last sequence update: | July 13, 2010 | |
Last modified: | February 10, 2021 | |
This is version 56 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |