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Protein
Submitted name:

Speckle-type POZ protein

Gene

SPOP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Speckle-type POZ proteinImported
Gene namesi
Name:SPOPImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000121067.17
HGNCiHGNC:11254 SPOP

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000121067

PTM / Processingi

Proteomic databases

MaxQBiD6RFL7
PeptideAtlasiD6RFL7
PRIDEiD6RFL7

Expressioni

Gene expression databases

BgeeiENSG00000121067 Expressed in 244 organ(s), highest expression level in vagina
ExpressionAtlasiD6RFL7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD6RFL7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 117MATHInterPro annotationAdd BLAST87

Phylogenomic databases

eggNOGiKOG1987 Eukaryota
ENOG410XQV8 LUCA
GeneTreeiENSGT00390000000361
HOGENOMiHOG000213970

Family and domain databases

Gene3Di2.60.210.10, 1 hit
InterProiView protein in InterPro
IPR002083 MATH/TRAF_dom
IPR008974 TRAF-like
SUPFAMiSSF49599 SSF49599, 1 hit
PROSITEiView protein in PROSITE
PS50144 MATH, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

D6RFL7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRVPSPPPP AEMSSGPVAE SWCYTQIKVV KFSYMWTINN FSFCREEMGE
60 70 80 90 100
VIKSSTFSSG ANDKLKWCLR VNPKGLDEES KDYLSLYLLL VSCPKSEVRA
110
KFKFSILNAK GEETKAM
Length:117
Mass (Da):13,229
Last modified:February 8, 2011 - v2
Checksum:i5461DE273C58B1D9
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O43791SPOP_HUMAN
Speckle-type POZ protein
SPOP
374Annotation score:
D6RDG8D6RDG8_HUMAN
Speckle-type POZ protein
SPOP
238Annotation score:
D6RDV6D6RDV6_HUMAN
Speckle-type POZ protein
SPOP
262Annotation score:
D6RBH6D6RBH6_HUMAN
Speckle-type POZ protein
SPOP
138Annotation score:
D6RGZ4D6RGZ4_HUMAN
Speckle-type POZ protein
SPOP
185Annotation score:
H0Y977H0Y977_HUMAN
Speckle-type POZ protein
SPOP
72Annotation score:
D6RD94D6RD94_HUMAN
Speckle-type POZ protein
SPOP
66Annotation score:
D6RIS7D6RIS7_HUMAN
Speckle-type POZ protein
SPOP
40Annotation score:
D6RA79D6RA79_HUMAN
Speckle-type POZ protein
SPOP
32Annotation score:
D6RBR3D6RBR3_HUMAN
Speckle-type POZ protein
SPOP
44Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei117Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006487 Genomic DNA No translation available.
AC015795 Genomic DNA No translation available.
KC877669 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000515508; ENSP00000426537; ENSG00000121067
UCSCiuc060hbw.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006487 Genomic DNA No translation available.
AC015795 Genomic DNA No translation available.
KC877669 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliD6RFL7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiD6RFL7
PeptideAtlasiD6RFL7
PRIDEiD6RFL7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000515508; ENSP00000426537; ENSG00000121067
UCSCiuc060hbw.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000121067.17
HGNCiHGNC:11254 SPOP
OpenTargetsiENSG00000121067
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1987 Eukaryota
ENOG410XQV8 LUCA
GeneTreeiENSGT00390000000361
HOGENOMiHOG000213970

Miscellaneous databases

ChiTaRSiSPOP human

Gene expression databases

BgeeiENSG00000121067 Expressed in 244 organ(s), highest expression level in vagina
ExpressionAtlasiD6RFL7 baseline and differential

Family and domain databases

Gene3Di2.60.210.10, 1 hit
InterProiView protein in InterPro
IPR002083 MATH/TRAF_dom
IPR008974 TRAF-like
SUPFAMiSSF49599 SSF49599, 1 hit
PROSITEiView protein in PROSITE
PS50144 MATH, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD6RFL7_HUMAN
AccessioniPrimary (citable) accession number: D6RFL7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: February 8, 2011
Last modified: September 12, 2018
This is version 48 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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