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Protein
Submitted name:

Monocyte differentiation antigen CD14

Gene

CD14

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Monocyte differentiation antigen CD14Imported
Gene namesi
Name:CD14Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000170458.13
HGNCiHGNC:1628 CD14

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000170458

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500308742420 – 213Sequence analysisAdd BLAST194

Proteomic databases

PeptideAtlasiD6RFL4
PRIDEiD6RFL4

Expressioni

Gene expression databases

BgeeiENSG00000170458 Expressed in 214 organ(s), highest expression level in liver
ExpressionAtlasiD6RFL4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD6RFL4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IXG9 Eukaryota
ENOG41118N2 LUCA
GeneTreeiENSGT00390000005689
HOGENOMiHOG000237268

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR032675 LRR_dom_sf
IPR016337 Monocyte_diff_Ag_CD14
PANTHERiPTHR10630 PTHR10630, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

D6RFL4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MERASCLLLL LLPLVHVSAT TPEPCELDDE DFRCVCNFSE PQPDWSEAFQ
60 70 80 90 100
CVSAVEVEIH AGGLNLEPFL KRVDADADPR QYADTVKALR VRRLTVGAAQ
110 120 130 140 150
VPAQLLVGAL RVLAYSRLKE LTLEDLKITG TMPPLPLEAT GLALSSLRLR
160 170 180 190 200
NVSWATGRSW LAELQQWLKP GLKVLSIAQA HSPAFSCEQV RAFPALTSLD
210
LSDNPGLGER GLM
Length:213
Mass (Da):23,313
Last modified:July 13, 2010 - v1
Checksum:i57C828B65C1A1CCF
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P08571CD14_HUMAN
Monocyte differentiation antigen CD...
CD14
375Annotation score:
D6RD81D6RD81_HUMAN
Monocyte differentiation antigen CD...
CD14
55Annotation score:
E7EVL5E7EVL5_HUMAN
Monocyte differentiation antigen CD...
CD14
81Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei213Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC116353 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000498971; ENSP00000426543; ENSG00000170458
UCSCiuc063hwn.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC116353 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliD6RFL4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiD6RFL4
PRIDEiD6RFL4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000498971; ENSP00000426543; ENSG00000170458
UCSCiuc063hwn.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000170458.13
HGNCiHGNC:1628 CD14
OpenTargetsiENSG00000170458
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IXG9 Eukaryota
ENOG41118N2 LUCA
GeneTreeiENSGT00390000005689
HOGENOMiHOG000237268

Miscellaneous databases

ChiTaRSiCD14 human

Gene expression databases

BgeeiENSG00000170458 Expressed in 214 organ(s), highest expression level in liver
ExpressionAtlasiD6RFL4 baseline and differential

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR032675 LRR_dom_sf
IPR016337 Monocyte_diff_Ag_CD14
PANTHERiPTHR10630 PTHR10630, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD6RFL4_HUMAN
AccessioniPrimary (citable) accession number: D6RFL4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: September 12, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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