UniProtKB - D6RFL4 (D6RFL4_HUMAN)
Protein
Monocyte differentiation antigen CD14
Gene
CD14
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Monocyte differentiation antigen CD14ARBA annotationAlternative name(s): Myeloid cell-specific leucine-rich glycoproteinARBA annotation |
Gene namesi | Name:CD14Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000170458.13 |
HGNCi | HGNC:1628, CD14 |
Subcellular locationi
Plasma membrane
- Cell membrane ARBA annotation; GPI-anchor ARBA annotation
Golgi apparatus
- Golgi apparatus ARBA annotation
Extracellular region or secreted
- Secreted ARBA annotation
Other locations
- Membrane raft ARBA annotation
- Membrane ARBA annotation; GPI-anchor ARBA annotation
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Golgi apparatus
- Golgi apparatus Source: UniProtKB-SubCell
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- membrane raft Source: UniProtKB-SubCell
Keywords - Cellular componenti
Golgi apparatusARBA annotation, SecretedARBA annotationPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | Sequence analysisAdd BLAST | 19 | |
ChainiPRO_5003087424 | 20 – 213 | Monocyte differentiation antigen CD14Sequence analysisAdd BLAST | 194 |
Keywords - PTMi
LipoproteinARBA annotationProteomic databases
PeptideAtlasi | D6RFL4 |
PRIDEi | D6RFL4 |
ProteomicsDBi | 14567 |
Expressioni
Gene expression databases
Bgeei | ENSG00000170458, Expressed in monocyte and 229 other tissues |
ExpressionAtlasi | D6RFL4, baseline and differential |
Family & Domainsi
Keywords - Domaini
RepeatARBA annotation, SignalSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00390000005689 |
HOGENOMi | CLU_1357365_0_0_1 |
Family and domain databases
Gene3Di | 3.80.10.10, 1 hit |
InterProi | View protein in InterPro IPR032675, LRR_dom_sf IPR016337, Monocyte_diff_Ag_CD14 |
PANTHERi | PTHR10630, PTHR10630, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
D6RFL4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MERASCLLLL LLPLVHVSAT TPEPCELDDE DFRCVCNFSE PQPDWSEAFQ
60 70 80 90 100
CVSAVEVEIH AGGLNLEPFL KRVDADADPR QYADTVKALR VRRLTVGAAQ
110 120 130 140 150
VPAQLLVGAL RVLAYSRLKE LTLEDLKITG TMPPLPLEAT GLALSSLRLR
160 170 180 190 200
NVSWATGRSW LAELQQWLKP GLKVLSIAQA HSPAFSCEQV RAFPALTSLD
210
LSDNPGLGER GLM
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP08571 | CD14_HUMAN | Monocyte differentiation antigen CD... | CD14 | 375 | Annotation score: | ||
E7EVL5 | E7EVL5_HUMAN | Monocyte differentiation antigen CD... | CD14 | 81 | Annotation score: | ||
D6RD81 | D6RD81_HUMAN | Monocyte differentiation antigen CD... | CD14 | 55 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 213 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC116353 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000498971; ENSP00000426543; ENSG00000170458 |
UCSCi | uc063hwn.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC116353 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | D6RFL4 |
PRIDEi | D6RFL4 |
ProteomicsDBi | 14567 |
Protocols and materials databases
Antibodypediai | 798, 3484 antibodies |
Genome annotation databases
Ensembli | ENST00000498971; ENSP00000426543; ENSG00000170458 |
UCSCi | uc063hwn.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000170458.13 |
HGNCi | HGNC:1628, CD14 |
OpenTargetsi | ENSG00000170458 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000005689 |
HOGENOMi | CLU_1357365_0_0_1 |
Miscellaneous databases
ChiTaRSi | CD14, human |
Gene expression databases
Bgeei | ENSG00000170458, Expressed in monocyte and 229 other tissues |
ExpressionAtlasi | D6RFL4, baseline and differential |
Family and domain databases
Gene3Di | 3.80.10.10, 1 hit |
InterProi | View protein in InterPro IPR032675, LRR_dom_sf IPR016337, Monocyte_diff_Ag_CD14 |
PANTHERi | PTHR10630, PTHR10630, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D6RFL4_HUMAN | |
Accessioni | D6RFL4Primary (citable) accession number: D6RFL4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 13, 2010 |
Last sequence update: | July 13, 2010 | |
Last modified: | October 7, 2020 | |
This is version 61 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |