UniProtKB - D6REM6 (D6REM6_HUMAN)
Protein
Submitted name:
Matrin-3
Gene
MATR3
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- RNA binding Source: UniProtKB-UniRule
- zinc ion binding Source: InterPro
Keywordsi
Molecular function | RNA-bindingPROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Matrin-3Imported |
Gene namesi | Name:MATR3Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000015479.17 |
HGNCi | HGNC:6912, MATR3 |
PTM / Processingi
Proteomic databases
MaxQBi | D6REM6 |
PeptideAtlasi | D6REM6 |
PRIDEi | D6REM6 |
ProteomicsDBi | 14342 |
PTM databases
SwissPalmi | D6REM6 |
Expressioni
Gene expression databases
Bgeei | ENSG00000015479, Expressed in frontal cortex and 121 other tissues |
ExpressionAtlasi | D6REM6, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 398 – 473 | RRMInterPro annotationAdd BLAST | 76 | |
Domaini | 496 – 571 | RRMInterPro annotationAdd BLAST | 76 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 146 – 174 | DisorderedSequence analysisAdd BLAST | 29 | |
Regioni | 187 – 214 | DisorderedSequence analysisAdd BLAST | 28 | |
Regioni | 342 – 394 | DisorderedSequence analysisAdd BLAST | 53 | |
Regioni | 588 – 794 | DisorderedSequence analysisAdd BLAST | 207 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 588 – 647 | PolyampholyteSequence analysisAdd BLAST | 60 | |
Compositional biasi | 648 – 664 | AcidicSequence analysisAdd BLAST | 17 | |
Compositional biasi | 690 – 735 | PolyampholyteSequence analysisAdd BLAST | 46 | |
Compositional biasi | 749 – 777 | PolyampholyteSequence analysisAdd BLAST | 29 |
Phylogenomic databases
GeneTreei | ENSGT00940000153322 |
Family and domain databases
CDDi | cd12714, RRM1_MATR3, 1 hit cd12715, RRM2_MATR3, 1 hit |
Gene3Di | 3.30.70.330, 2 hits |
InterProi | View protein in InterPro IPR034928, MATR3_RRM1 IPR034930, MATR3_RRM2 IPR003604, Matrin/U1-like-C_Znf_C2H2 IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom |
SMARTi | View protein in SMART SM00360, RRM, 2 hits SM00451, ZnF_U1, 1 hit |
SUPFAMi | SSF54928, SSF54928, 2 hits |
PROSITEi | View protein in PROSITE PS50102, RRM, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 20 potential isoforms that are computationally mapped.Show allAlign All
D6REM6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSKSFQQSSL SRDSQGHGRD LSAAGIGLLA AATQSLSMPA SLGRMNQGTA
60 70 80 90 100
RLASLMNLGM SSSLNQQGAH SALSSASTSS HNLQSIFNIG SRGPLPLSSQ
110 120 130 140 150
HRGDADQASN ILASFGLSAR DLDELSRYPE DKITPENLPQ ILLQLKRRRT
160 170 180 190 200
EEGPTLSYGR DGRSATREPP YRVPRDDWEE KRHFRRDSFD DRGPSLNPVL
210 220 230 240 250
DYDHGSRSQE SGYYDRMDYE DDRLRDGERC RDDSFFGETS HNYHKFDSEY
260 270 280 290 300
ERMGRGPGPL QERSLFEKKR GAPPSSNIED FHGLLPKGYP HLCSICDLPV
310 320 330 340 350
HSNKEWSQHI NGASHSRRCQ LLLEIYPEWN PDNDTGHTMG DPFMLQQSTN
360 370 380 390 400
PAPGILGPPP PSFHLGGPAV GPRGNLGAGN GNLQGPRHMQ KGRVETSRVV
410 420 430 440 450
HIMDFQRGKN LRYQLLQLVE PFGVISNHLI LNKINEAFIE MATTEDAQAA
460 470 480 490 500
VDYYTTTPAL VFGKPVRVHL SQKYKRIKKP EGKPDQKFDQ KQELGRVIHL
510 520 530 540 550
SNLPHSGYSD SAVLKLAEPY GKIKNYILMR MKSQAFIEME TREDAMAMVD
560 570 580 590 600
HCLKKALWFQ GRCVKVDLSE KYKKLVLRIP NRGIDLLKKD KSRKRSYSPD
610 620 630 640 650
GKESPSDKKS KTDGSQKTES STEGKEQEEK SGEDGEKDTK DDQTEQEPNM
660 670 680 690 700
LLESEDELLV DEEEAAALLE SGSSVGDETD LANLGDVASD GKKEPSDKAV
710 720 730 740 750
KKDGSASAAA KKKLKKVDKI EELDQENEAA LENGIKNEEN TEPGAESSEN
760 770 780 790
ADDPNKDTSE NADGQSDENK DDYTIPDEYR IGPYQPNVPV EISE
Computationally mapped potential isoform sequencesi
There are 20 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP43243 | MATR3_HUMAN | Matrin-3 | MATR3 KIAA0723 | 847 | Annotation score: | ||
B3KM87 | B3KM87_HUMAN | Matrin-3 | MATR3 | 509 | Annotation score: | ||
A0A0R4J2E8 | A0A0R4J2E8_HUMAN | Matrin-3 | MATR3 | 847 | Annotation score: | ||
A8MXP9 | A8MXP9_HUMAN | Matrin-3 | MATR3 | 895 | Annotation score: | ||
H0Y8T4 | H0Y8T4_HUMAN | Matrin-3 | MATR3 | 334 | Annotation score: | ||
D6R991 | D6R991_HUMAN | Matrin-3 | MATR3 | 433 | Annotation score: | ||
D6RBI2 | D6RBI2_HUMAN | Matrin-3 | MATR3 | 109 | Annotation score: | ||
D6RE02 | D6RE02_HUMAN | Matrin-3 | MATR3 | 124 | Annotation score: | ||
D6RBK5 | D6RBK5_HUMAN | Matrin-3 | MATR3 | 121 | Annotation score: | ||
D6RIA2 | D6RIA2_HUMAN | Matrin-3 | MATR3 | 172 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC011404 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000510056; ENSP00000426743; ENSG00000015479 |
UCSCi | uc063hpp.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC011404 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | D6REM6, 1 interactor |
MINTi | D6REM6 |
PTM databases
SwissPalmi | D6REM6 |
Proteomic databases
MaxQBi | D6REM6 |
PeptideAtlasi | D6REM6 |
PRIDEi | D6REM6 |
ProteomicsDBi | 14342 |
Protocols and materials databases
Antibodypediai | 15070, 218 antibodies |
Genome annotation databases
Ensembli | ENST00000510056; ENSP00000426743; ENSG00000015479 |
UCSCi | uc063hpp.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000015479.17 |
HGNCi | HGNC:6912, MATR3 |
OpenTargetsi | ENSG00000015479 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000153322 |
Miscellaneous databases
ChiTaRSi | MATR3, human |
Gene expression databases
Bgeei | ENSG00000015479, Expressed in frontal cortex and 121 other tissues |
ExpressionAtlasi | D6REM6, baseline and differential |
Family and domain databases
CDDi | cd12714, RRM1_MATR3, 1 hit cd12715, RRM2_MATR3, 1 hit |
Gene3Di | 3.30.70.330, 2 hits |
InterProi | View protein in InterPro IPR034928, MATR3_RRM1 IPR034930, MATR3_RRM2 IPR003604, Matrin/U1-like-C_Znf_C2H2 IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom |
SMARTi | View protein in SMART SM00360, RRM, 2 hits SM00451, ZnF_U1, 1 hit |
SUPFAMi | SSF54928, SSF54928, 2 hits |
PROSITEi | View protein in PROSITE PS50102, RRM, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D6REM6_HUMAN | |
Accessioni | D6REM6Primary (citable) accession number: D6REM6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 13, 2010 |
Last sequence update: | July 13, 2010 | |
Last modified: | August 12, 2020 | |
This is version 78 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |