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UniProtKB - D6RE84 (D6RE84_HUMAN)
Protein
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase
Gene
ALG13
Organism
Homo sapiens (Human)
Status
Functioni
Catalytic activityi
- N-acetyl-α-D-glucosaminyl-diphosphodolichol + UDP-N-acetyl-α-D-glucosamine = H+ + N,N'-diacetylchitobiosyl diphosphodolichol + UDPARBA annotationEC:2.4.1.141ARBA annotation
GO - Molecular functioni
- N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity Source: UniProtKB-EC
GO - Biological processi
- dolichol-linked oligosaccharide biosynthetic process Source: InterPro
Names & Taxonomyi
Protein namesi | Recommended name: N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferaseARBA annotation (EC:2.4.1.141ARBA annotation) |
Gene namesi | Name:ALG13Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:30881, ALG13 |
VEuPathDBi | HostDB:ENSG00000101901 |
Expressioni
Gene expression databases
Bgeei | ENSG00000101901, Expressed in female gonad and 230 other tissues |
ExpressionAtlasi | D6RE84, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 4 – 126 | Glyco_tran_28_CInterPro annotationAdd BLAST | 123 |
Sequence similaritiesi
Belongs to the glycosyltransferase 28 family.ARBA annotation
Phylogenomic databases
GeneTreei | ENSGT00940000159922 |
Family and domain databases
InterProi | View protein in InterPro IPR039042, Alg13-like IPR007235, Glyco_trans_28_C |
PANTHERi | PTHR12867, PTHR12867, 1 hit |
Pfami | View protein in Pfam PF04101, Glyco_tran_28_C, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 14 potential isoforms that are computationally mapped.Show allAlign All
D6RE84-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKCVFVTVGT TSFDDLIACV SAPDSLQKIE SLGYNRLILQ IGRGTVVPEP
60 70 80 90 100
FSTESFTLDV YRYKDSLKED IQKADLVISH AGAGSCLETL EKGKPLVVVI
110 120 130 140 150
NEKLMNNHQL ELAKQLHKEG HLFYCTCRLI LKKCLLVVEG GDKEILWVAG
GSQLGLKFC
Computationally mapped potential isoform sequencesi
There are 14 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9NP73 | ALG13_HUMAN | Putative bifunctional UDP-N-acetylg... | ALG13 CXorf45, GLT28D1, MDS031 | 1,137 | Annotation score: | ||
A0A087WX43 | A0A087WX43_HUMAN | N-acetylglucosaminyldiphosphodolich... | ALG13 | 133 | Annotation score: | ||
A0A096LNJ4 | A0A096LNJ4_HUMAN | N-acetylglucosaminyldiphosphodolich... | ALG13 | 132 | Annotation score: | ||
A0A087WTT9 | A0A087WTT9_HUMAN | N-acetylglucosaminyldiphosphodolich... | ALG13 | 171 | Annotation score: | ||
A0A096LP10 | A0A096LP10_HUMAN | N-acetylglucosaminyldiphosphodolich... | ALG13 | 162 | Annotation score: | ||
A0A087WT15 | A0A087WT15_HUMAN | N-acetylglucosaminyldiphosphodolich... | ALG13 | 61 | Annotation score: | ||
A0A096LNL2 | A0A096LNL2_HUMAN | N-acetylglucosaminyldiphosphodolich... | ALG13 | 150 | Annotation score: | ||
A0A096LP54 | A0A096LP54_HUMAN | N-acetylglucosaminyldiphosphodolich... | ALG13 | 42 | Annotation score: | ||
A0A1B0GVW6 | A0A1B0GVW6_HUMAN | Putative bifunctional UDP-N-acetylg... | ALG13 | 296 | Annotation score: | ||
A0A096LPI3 | A0A096LPI3_HUMAN | Putative bifunctional UDP-N-acetylg... | ALG13 | 373 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL049563 Genomic DNA No translation available. AL096764 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000486353; ENSP00000426892; ENSG00000101901 |
UCSCi | uc065asu.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL049563 Genomic DNA No translation available. AL096764 Genomic DNA No translation available. |
3D structure databases
SMRi | D6RE84 |
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | D6RE84 |
ProteomicsDBi | 14253 |
Genome annotation databases
Ensembli | ENST00000486353; ENSP00000426892; ENSG00000101901 |
UCSCi | uc065asu.1, human |
Organism-specific databases
HGNCi | HGNC:30881, ALG13 |
OpenTargetsi | ENSG00000101901 |
VEuPathDBi | HostDB:ENSG00000101901 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000159922 |
Miscellaneous databases
ChiTaRSi | ALG13, human |
Gene expression databases
Bgeei | ENSG00000101901, Expressed in female gonad and 230 other tissues |
ExpressionAtlasi | D6RE84, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR039042, Alg13-like IPR007235, Glyco_trans_28_C |
PANTHERi | PTHR12867, PTHR12867, 1 hit |
Pfami | View protein in Pfam PF04101, Glyco_tran_28_C, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | D6RE84_HUMAN | |
Accessioni | D6RE84Primary (citable) accession number: D6RE84 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 13, 2010 |
Last sequence update: | November 26, 2014 | |
Last modified: | January 19, 2022 | |
This is version 61 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |