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UniProtKB - D6RE65 (D6RE65_HUMAN)
Protein
Submitted name:
Calcium/calmodulin-dependent protein kinase type IV
Gene
CAMK4
Organism
Homo sapiens (Human)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 75 | ATPPROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- protein kinase activity Source: InterPro
Keywordsi
Ligand | ATP-bindingPROSITE-ProRule annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: Calcium/calmodulin-dependent protein kinase type IVImported |
Gene namesi | Name:CAMK4Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:1464, CAMK4 |
VEuPathDBi | HostDB:ENSG00000152495 |
Expressioni
Gene expression databases
Bgeei | ENSG00000152495, Expressed in caudate nucleus and 164 other tissues |
ExpressionAtlasi | D6RE65, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 46 – 142 | Protein kinaseInterPro annotationAdd BLAST | 97 |
Phylogenomic databases
GeneTreei | ENSGT00940000160006 |
OMAi | AAPEYWI |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
D6RE65-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLKVTVPSCS ASSCSSVTAS AAPGTASLVP DYWIDGSNRD ALSDFFEVES
60 70 80 90 100
ELGRGATSIV YRCKQKGTQK PYALKVLKKT VDKKIVRTEI GVLLRLSHPN
110 120 130 140
IIKLKEIFET PTEISLVLEL VTGGELFDRI VEKGYYSERD AA
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ16566 | KCC4_HUMAN | Calcium/calmodulin-dependent protei... | CAMK4 CAMK, CAMK-GR, CAMKIV | 473 | Annotation score: | ||
D6REY7 | D6REY7_HUMAN | Calcium/calmodulin-dependent protei... | CAMK4 | 109 | Annotation score: | ||
D6RCD6 | D6RCD6_HUMAN | Calcium/calmodulin-dependent protei... | CAMK4 | 88 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 142 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC010275 Genomic DNA No translation available. AC010468 Genomic DNA No translation available. AC011422 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000508074; ENSP00000426940; ENSG00000152495 |
UCSCi | uc063fyd.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC010275 Genomic DNA No translation available. AC010468 Genomic DNA No translation available. AC011422 Genomic DNA No translation available. |
3D structure databases
SMRi | D6RE65 |
ModBasei | Search... |
Proteomic databases
MaxQBi | D6RE65 |
PeptideAtlasi | D6RE65 |
ProteomicsDBi | 14235 |
Protocols and materials databases
Antibodypediai | 2084, 626 antibodies from 42 providers |
Genome annotation databases
Ensembli | ENST00000508074; ENSP00000426940; ENSG00000152495 |
UCSCi | uc063fyd.1, human |
Organism-specific databases
HGNCi | HGNC:1464, CAMK4 |
OpenTargetsi | ENSG00000152495 |
VEuPathDBi | HostDB:ENSG00000152495 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000160006 |
OMAi | AAPEYWI |
Miscellaneous databases
ChiTaRSi | CAMK4, human |
Gene expression databases
Bgeei | ENSG00000152495, Expressed in caudate nucleus and 164 other tissues |
ExpressionAtlasi | D6RE65, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | D6RE65_HUMAN | |
Accessioni | D6RE65Primary (citable) accession number: D6RE65 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 13, 2010 |
Last sequence update: | July 13, 2010 | |
Last modified: | January 19, 2022 | |
This is version 70 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |