UniProtKB - D6RDJ6 (D6RDJ6_HUMAN)
Protein
Submitted name:
Threonine--tRNA ligase 1, cytoplasmic
Gene
TARS1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: InterPro
- threonine-tRNA ligase activity Source: InterPro
GO - Biological processi
- threonyl-tRNA aminoacylation Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Threonine--tRNA ligase 1, cytoplasmicImported |
Gene namesi | Name:TARS1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000113407.13 |
HGNCi | HGNC:11572, TARS1 |
Subcellular locationi
Other locations
- cytoplasm Source: InterPro
PTM / Processingi
Proteomic databases
EPDi | D6RDJ6 |
MaxQBi | D6RDJ6 |
PeptideAtlasi | D6RDJ6 |
PRIDEi | D6RDJ6 |
ProteomicsDBi | 14118 |
Expressioni
Gene expression databases
Bgeei | ENSG00000113407, Expressed in adrenal tissue and 243 other tissues |
ExpressionAtlasi | D6RDJ6, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 47 | DisorderedSequence analysisAdd BLAST | 47 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 18 – 41 | PolyampholyteSequence analysisAdd BLAST | 24 |
Phylogenomic databases
GeneTreei | ENSGT00940000154969 |
HOGENOMi | CLU_1953702_0_0_1 |
Family and domain databases
Gene3Di | 3.10.20.30, 1 hit |
InterProi | View protein in InterPro IPR012675, Beta-grasp_dom_sf IPR002320, Thr-tRNA-ligase_IIa |
PANTHERi | PTHR11451, PTHR11451, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
D6RDJ6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFEEKASSPS GKMGGEEKPI GAGEEKQKEG GKKKNKEGSG DGGRAELNPW
60 70 80 90 100
PEYIYTRLEM YNILKAEHDS ILAEKAEKDS KPIKVTLPDG KQVDAESWKT
110 120 130
TPYQIACGIS HGKSLWWMFM LRSANRKWIL L
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP26639 | SYTC_HUMAN | Threonine--tRNA ligase 1, cytoplasm... | TARS1 TARS | 723 | Annotation score: | ||
D6R9F8 | D6R9F8_HUMAN | Threonine--tRNA ligase 1, cytoplasm... | TARS1 | 129 | Annotation score: | ||
D6RCA5 | D6RCA5_HUMAN | Threonine--tRNA ligase 1, cytoplasm... | TARS1 | 118 | Annotation score: | ||
D6RBR8 | D6RBR8_HUMAN | Threonine--tRNA ligase 1, cytoplasm... | TARS1 | 50 | Annotation score: | ||
D6RCS6 | D6RCS6_HUMAN | Threonine--tRNA ligase 1, cytoplasm... | TARS1 | 66 | Annotation score: | ||
D6RHV7 | D6RHV7_HUMAN | Threonine--tRNA ligase 1, cytoplasm... | TARS1 | 56 | Annotation score: | ||
D6RJ97 | D6RJ97_HUMAN | Threonine--tRNA ligase 1, cytoplasm... | TARS1 | 55 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC025441 Genomic DNA No translation available. AC034231 Genomic DNA No translation available. KF510921 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000507716; ENSP00000420893; ENSG00000113407 |
UCSCi | uc063cuo.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC025441 Genomic DNA No translation available. AC034231 Genomic DNA No translation available. KF510921 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
EPDi | D6RDJ6 |
MaxQBi | D6RDJ6 |
PeptideAtlasi | D6RDJ6 |
PRIDEi | D6RDJ6 |
ProteomicsDBi | 14118 |
Genome annotation databases
Ensembli | ENST00000507716; ENSP00000420893; ENSG00000113407 |
UCSCi | uc063cuo.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000113407.13 |
HGNCi | HGNC:11572, TARS1 |
OpenTargetsi | ENSG00000113407 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000154969 |
HOGENOMi | CLU_1953702_0_0_1 |
Miscellaneous databases
ChiTaRSi | TARS, human |
Gene expression databases
Bgeei | ENSG00000113407, Expressed in adrenal tissue and 243 other tissues |
ExpressionAtlasi | D6RDJ6, baseline and differential |
Family and domain databases
Gene3Di | 3.10.20.30, 1 hit |
InterProi | View protein in InterPro IPR012675, Beta-grasp_dom_sf IPR002320, Thr-tRNA-ligase_IIa |
PANTHERi | PTHR11451, PTHR11451, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D6RDJ6_HUMAN | |
Accessioni | D6RDJ6Primary (citable) accession number: D6RDJ6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 13, 2010 |
Last sequence update: | July 13, 2010 | |
Last modified: | December 2, 2020 | |
This is version 60 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |