UniProtKB - D6RDH4 (D6RDH4_HUMAN)
Protein
Submitted name:
Adenylate kinase isoenzyme 6
Gene
AK6
Organism
Homo sapiens (Human)
Status
Functioni
Catalytic activityi
- EC:2.7.4.3ARBA annotation
GO - Molecular functioni
- adenylate kinase activity Source: InterPro
- ATP binding Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Adenylate kinase isoenzyme 6Imported |
Gene namesi | Name:AK6Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:49151, AK6 |
VEuPathDBi | HostDB:ENSG00000085231.13 |
Subcellular locationi
Cytoskeleton
- centrosome Source: HPA
Cytosol
- cytosol Source: HPA
Nucleus
- nuclear speck Source: HPA
Expressioni
Gene expression databases
Bgeei | ENSG00000085231, Expressed in caudate nucleus and 235 other tissues |
ExpressionAtlasi | D6RDH4, baseline and differential |
Family & Domainsi
Phylogenomic databases
GeneTreei | ENSGT00390000015930 |
Family and domain databases
InterProi | View protein in InterPro IPR020618, Adenyl_kinase_AK6 IPR027417, P-loop_NTPase |
PANTHERi | PTHR12595:SF19, PTHR12595:SF19, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
D6RDH4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLLPNILLTE QLYDGYDEEY DCPILDEDRV VDELDNQMRE GGVIVDYHGC
60 70 80 90 100
DFFPERWFHI VFVLRTDTNV LYERLETRGY NEKKLTDNIQ CEIFQVLYEE
110 120 130 140
ATASYKEEIV HQLPSNKPEE LENNVDQILK WIEQWIKDHN S
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9Y3D8 | KAD6_HUMAN | Adenylate kinase isoenzyme 6 | AK6 CINAP, AD-004, CGI-137 | 172 | Annotation score: | ||
A0A087WVD7 | A0A087WVD7_HUMAN | Adenylate kinase isoenzyme 6 | AK6 | 109 | Annotation score: | ||
A0A087WY94 | A0A087WY94_HUMAN | Adenylate kinase isoenzyme 6 | AK6 | 47 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC145132 Genomic DNA No translation available. AC145145 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000512561; ENSP00000420947; ENSG00000085231 ENST00000617079; ENSP00000483874; ENSG00000279247 |
UCSCi | uc063egc.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC145132 Genomic DNA No translation available. AC145145 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | D6RDH4 |
PRIDEi | D6RDH4 |
ProteomicsDBi | 14099 |
Protocols and materials databases
Antibodypediai | 3945, 107 antibodies |
Genome annotation databases
Ensembli | ENST00000512561; ENSP00000420947; ENSG00000085231 ENST00000617079; ENSP00000483874; ENSG00000279247 |
UCSCi | uc063egc.1, human |
Organism-specific databases
HGNCi | HGNC:49151, AK6 |
OpenTargetsi | ENSG00000085231 |
VEuPathDBi | HostDB:ENSG00000085231.13 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000015930 |
Miscellaneous databases
ChiTaRSi | AK6, human |
Gene expression databases
Bgeei | ENSG00000085231, Expressed in caudate nucleus and 235 other tissues |
ExpressionAtlasi | D6RDH4, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR020618, Adenyl_kinase_AK6 IPR027417, P-loop_NTPase |
PANTHERi | PTHR12595:SF19, PTHR12595:SF19, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D6RDH4_HUMAN | |
Accessioni | D6RDH4Primary (citable) accession number: D6RDH4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 13, 2010 |
Last sequence update: | July 13, 2010 | |
Last modified: | February 10, 2021 | |
This is version 78 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |