Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Long-chain-fatty-acid--CoA ligase 4

Gene

ACSL4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Long-chain-fatty-acid--CoA ligase 4Imported
Gene namesi
Name:ACSL4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000068366.19
HGNCiHGNC:3571 ACSL4

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 32HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000068366

PTM / Processingi

Proteomic databases

MaxQBiD6RDA8
PeptideAtlasiD6RDA8
PRIDEiD6RDA8

Expressioni

Gene expression databases

BgeeiENSG00000068366 Expressed in 215 organ(s), highest expression level in adrenal tissue
ExpressionAtlasiD6RDA8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD6RDA8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1256 Eukaryota
COG1022 LUCA
GeneTreeiENSGT00930000150966

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

D6RDA8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKLKLNVLTI ILLPVHLLIT IYSALIFIPW YFLTNAKKKN AMAKRIKAKP
60 70 80 90 100
TSDKPGSPYR SVTHFDSLAV IDIPGADTLD KLFDHAVSKF GKKDSLGTRE
110 120
ILSEENEMQP NGKVFKKLIL GNYKWMNY
Length:128
Mass (Da):14,567
Last modified:July 13, 2010 - v1
Checksum:iCAE7E74C1E7390F1
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O60488ACSL4_HUMAN
Long-chain-fatty-acid--CoA ligase 4
ACSL4 ACS4, FACL4, LACS4
711Annotation score:
D6RFW9D6RFW9_HUMAN
Long-chain-fatty-acid--CoA ligase 4
ACSL4
126Annotation score:
D6RD96D6RD96_HUMAN
Long-chain-fatty-acid--CoA ligase 4
ACSL4
145Annotation score:
A0A0C4DGB7A0A0C4DGB7_HUMAN
Long-chain-fatty-acid--CoA ligase 4
ACSL4
54Annotation score:
D6RF95D6RF95_HUMAN
Long-chain-fatty-acid--CoA ligase 4
ACSL4
154Annotation score:
H0Y9A0H0Y9A0_HUMAN
Long-chain-fatty-acid--CoA ligase 4
ACSL4
156Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei128Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL118496 Genomic DNA No translation available.
AL138968 Genomic DNA No translation available.
KF459310 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000508092; ENSP00000425378; ENSG00000068366
UCSCiuc065arg.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL118496 Genomic DNA No translation available.
AL138968 Genomic DNA No translation available.
KF459310 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliD6RDA8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiD6RDA8
PeptideAtlasiD6RDA8
PRIDEiD6RDA8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000508092; ENSP00000425378; ENSG00000068366
UCSCiuc065arg.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000068366.19
HGNCiHGNC:3571 ACSL4
OpenTargetsiENSG00000068366
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1256 Eukaryota
COG1022 LUCA
GeneTreeiENSGT00930000150966

Miscellaneous databases

ChiTaRSiACSL4 human

Gene expression databases

BgeeiENSG00000068366 Expressed in 215 organ(s), highest expression level in adrenal tissue
ExpressionAtlasiD6RDA8 baseline and differential

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiD6RDA8_HUMAN
AccessioniPrimary (citable) accession number: D6RDA8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: November 7, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again