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UniProtKB - D6RCF1 (D6RCF1_HUMAN)
Protein
Submitted name:
cGMP-gated cation channel alpha-1
Gene
CNGA1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- intracellular cyclic nucleotide activated cation channel activity Source: InterPro
GO - Biological processi
- visual perception Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: cGMP-gated cation channel alpha-1 |
Gene namesi | Name:CNGA1 |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:2148, CNGA1 |
VEuPathDBi | HostDB:ENSG00000198515 |
Expressioni
Gene expression databases
Bgeei | ENSG00000198515, Expressed in amniotic fluid and 135 other tissues |
ExpressionAtlasi | D6RCF1, baseline and differential |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 31 – 124 | DisorderedSequence analysisAdd BLAST | 94 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 94 – 124 | Basic and acidic residuesSequence analysisAdd BLAST | 31 |
Phylogenomic databases
GeneTreei | ENSGT00940000156074 |
HOGENOMi | CLU_161070_0_0_1 |
OMAi | IEFEGRH |
Family and domain databases
InterProi | View protein in InterPro IPR032945, CNGA1 |
PANTHERi | PTHR45638:SF9, PTHR45638:SF9, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
D6RCF1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKNNIINTQQ SFVTMPNVIV PDIEKEIRRM ENGACSSFSE DDDSASTSEE
60 70 80 90 100
SENENPHARG SFSYKSLRKG GPSQREQYLP GAIALFNVNN SSNKDQEPEE
110 120
KKKKKKEKKS KSDDKNENKN DPEK
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP29973 | CNGA1_HUMAN | cGMP-gated cation channel alpha-1 | CNGA1 CNCG, CNCG1 | 686 | Annotation score: | ||
D6R978 | D6R978_HUMAN | cGMP-gated cation channel alpha-1 | CNGA1 | 95 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 124 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC096749 Genomic DNA No translation available. AC107068 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000504722.6; ENSP00000423721.2; ENSG00000198515.16 |
UCSCi | uc062wkg.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC096749 Genomic DNA No translation available. AC107068 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 23791, 101 antibodies from 23 providers |
Genome annotation databases
Ensembli | ENST00000504722.6; ENSP00000423721.2; ENSG00000198515.16 |
UCSCi | uc062wkg.1, human |
Organism-specific databases
HGNCi | HGNC:2148, CNGA1 |
OpenTargetsi | ENSG00000198515 |
VEuPathDBi | HostDB:ENSG00000198515 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000156074 |
HOGENOMi | CLU_161070_0_0_1 |
OMAi | IEFEGRH |
Miscellaneous databases
ChiTaRSi | CNGA1, human |
Gene expression databases
Bgeei | ENSG00000198515, Expressed in amniotic fluid and 135 other tissues |
ExpressionAtlasi | D6RCF1, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR032945, CNGA1 |
PANTHERi | PTHR45638:SF9, PTHR45638:SF9, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | D6RCF1_HUMAN | |
Accessioni | D6RCF1Primary (citable) accession number: D6RCF1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 13, 2010 |
Last sequence update: | April 7, 2021 | |
Last modified: | May 25, 2022 | |
This is version 65 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |