UniProtKB - D6RCA5 (D6RCA5_HUMAN)
Protein
Submitted name:
Threonine--tRNA ligase 1, cytoplasmic
Gene
TARS1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: InterPro
- threonine-tRNA ligase activity Source: InterPro
GO - Biological processi
- threonyl-tRNA aminoacylation Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Threonine--tRNA ligase 1, cytoplasmicImported |
Gene namesi | Name:TARS1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000113407.13 |
HGNCi | HGNC:11572, TARS1 |
Subcellular locationi
Other locations
- cytoplasm Source: InterPro
PTM / Processingi
Proteomic databases
MaxQBi | D6RCA5 |
PeptideAtlasi | D6RCA5 |
PRIDEi | D6RCA5 |
ProteomicsDBi | 13868 |
Expressioni
Gene expression databases
Bgeei | ENSG00000113407, Expressed in adrenal tissue and 243 other tissues |
ExpressionAtlasi | D6RCA5, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 48 | DisorderedSequence analysisAdd BLAST | 48 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 18 – 41 | PolyampholyteSequence analysisAdd BLAST | 24 |
Phylogenomic databases
GeneTreei | ENSGT00940000154969 |
Family and domain databases
Gene3Di | 3.10.20.30, 1 hit |
InterProi | View protein in InterPro IPR012675, Beta-grasp_dom_sf IPR002320, Thr-tRNA-ligase_IIa |
PANTHERi | PTHR11451, PTHR11451, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
D6RCA5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFEEKASSPS GKMGGEEKPI GAGEEKQKEG GKKKNKEGSG DGGRAELNPW
60 70 80 90 100
PEYIYTRLEM YNILKAEHDS ILAEKAEKDS KPIKVTLPDG KQVDAESWKT
110
TPYQIACGIR PGRQHRYC
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP26639 | SYTC_HUMAN | Threonine--tRNA ligase 1, cytoplasm... | TARS1 TARS | 723 | Annotation score: | ||
D6R9F8 | D6R9F8_HUMAN | Threonine--tRNA ligase 1, cytoplasm... | TARS1 | 129 | Annotation score: | ||
D6RDJ6 | D6RDJ6_HUMAN | Threonine--tRNA ligase 1, cytoplasm... | TARS1 | 131 | Annotation score: | ||
D6RBR8 | D6RBR8_HUMAN | Threonine--tRNA ligase 1, cytoplasm... | TARS1 | 50 | Annotation score: | ||
D6RCS6 | D6RCS6_HUMAN | Threonine--tRNA ligase 1, cytoplasm... | TARS1 | 66 | Annotation score: | ||
D6RHV7 | D6RHV7_HUMAN | Threonine--tRNA ligase 1, cytoplasm... | TARS1 | 56 | Annotation score: | ||
D6RJ97 | D6RJ97_HUMAN | Threonine--tRNA ligase 1, cytoplasm... | TARS1 | 55 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC025441 Genomic DNA No translation available. AC034231 Genomic DNA No translation available. KF510921 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000505012; ENSP00000422291; ENSG00000113407 |
UCSCi | uc063cuq.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC025441 Genomic DNA No translation available. AC034231 Genomic DNA No translation available. KF510921 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | D6RCA5 |
PeptideAtlasi | D6RCA5 |
PRIDEi | D6RCA5 |
ProteomicsDBi | 13868 |
Genome annotation databases
Ensembli | ENST00000505012; ENSP00000422291; ENSG00000113407 |
UCSCi | uc063cuq.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000113407.13 |
HGNCi | HGNC:11572, TARS1 |
OpenTargetsi | ENSG00000113407 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000154969 |
Miscellaneous databases
ChiTaRSi | TARS, human |
Gene expression databases
Bgeei | ENSG00000113407, Expressed in adrenal tissue and 243 other tissues |
ExpressionAtlasi | D6RCA5, baseline and differential |
Family and domain databases
Gene3Di | 3.10.20.30, 1 hit |
InterProi | View protein in InterPro IPR012675, Beta-grasp_dom_sf IPR002320, Thr-tRNA-ligase_IIa |
PANTHERi | PTHR11451, PTHR11451, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D6RCA5_HUMAN | |
Accessioni | D6RCA5Primary (citable) accession number: D6RCA5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 13, 2010 |
Last sequence update: | July 13, 2010 | |
Last modified: | December 2, 2020 | |
This is version 60 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |