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Protein
Submitted name:

BRCA1-A complex subunit RAP80

Gene

UIMC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
BRCA1-A complex subunit RAP80Imported
Gene namesi
Name:UIMC1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000087206.16
HGNCiHGNC:30298 UIMC1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000087206

PTM / Processingi

Proteomic databases

MaxQBiD6RC40
PeptideAtlasiD6RC40
PRIDEiD6RC40

Expressioni

Gene expression databases

BgeeiENSG00000087206 Expressed in 209 organ(s), highest expression level in testis
ExpressionAtlasiD6RC40 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliD6RC40
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili89 – 116Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IGE5 Eukaryota
ENOG4111MI8 LUCA
GeneTreeiENSGT00390000007635
HOGENOMiHOG000154772

Family and domain databases

InterProiView protein in InterPro
IPR038868 RAP80
IPR003903 UIM_dom
PANTHERiPTHR15932 PTHR15932, 1 hit
PfamiView protein in Pfam
PF02809 UIM, 2 hits
SMARTiView protein in SMART
SM00726 UIM, 2 hits
PROSITEiView protein in PROSITE
PS50330 UIM, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

D6RC40-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPRRKKKVKE VSESRNLEKK DVETTSSVSV KRKRRLEDAF IVISDSDGEE
60 70 80 90 100
PKEENGLQKT KTKQSNRAKC LAKRKIAQMT EEEQFALALK MSEQEAREVN
110 120 130 140 150
SQEEEEEELL RKAIAESLNS CRPSDASATR SRPLATGPSS QSHQEKTTDS

GLTEGIW
Length:157
Mass (Da):17,752
Last modified:July 13, 2010 - v1
Checksum:i7F1EDEA98644C54A
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q96RL1UIMC1_HUMAN
BRCA1-A complex subunit RAP80
UIMC1 RAP80, RXRIP110
719Annotation score:
D6RCQ3D6RCQ3_HUMAN
BRCA1-A complex subunit RAP80
UIMC1
166Annotation score:
D6RDZ5D6RDZ5_HUMAN
BRCA1-A complex subunit RAP80
UIMC1
89Annotation score:
D6R9M3D6R9M3_HUMAN
BRCA1-A complex subunit RAP80
UIMC1
31Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei157Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC027317 Genomic DNA No translation available.
AC027318 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000509236; ENSP00000423885; ENSG00000087206
UCSCiuc063kat.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC027317 Genomic DNA No translation available.
AC027318 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliD6RC40
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiD6RC40
PeptideAtlasiD6RC40
PRIDEiD6RC40

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000509236; ENSP00000423885; ENSG00000087206
UCSCiuc063kat.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000087206.16
HGNCiHGNC:30298 UIMC1
OpenTargetsiENSG00000087206
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IGE5 Eukaryota
ENOG4111MI8 LUCA
GeneTreeiENSGT00390000007635
HOGENOMiHOG000154772

Miscellaneous databases

ChiTaRSiUIMC1 human

Gene expression databases

BgeeiENSG00000087206 Expressed in 209 organ(s), highest expression level in testis
ExpressionAtlasiD6RC40 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR038868 RAP80
IPR003903 UIM_dom
PANTHERiPTHR15932 PTHR15932, 1 hit
PfamiView protein in Pfam
PF02809 UIM, 2 hits
SMARTiView protein in SMART
SM00726 UIM, 2 hits
PROSITEiView protein in PROSITE
PS50330 UIM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD6RC40_HUMAN
AccessioniPrimary (citable) accession number: D6RC40
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: September 12, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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