UniProtKB - D6RB81 (D6RB81_HUMAN)
Protein
Submitted name:
Alpha-methylacyl-CoA racemase
Gene
AMACR
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Alpha-methylacyl-CoA racemaseImported |
Gene namesi | Name:AMACRImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000242110.7 |
HGNCi | HGNC:451, AMACR |
Subcellular locationi
Plasma Membrane
- plasma membrane Source: HPA
Other locations
- intracellular membrane-bounded organelle Source: HPA
Pathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000242110 |
Chemistry databases
DrugBanki | DB09213, Dexibuprofen DB01050, Ibuprofen |
PTM / Processingi
Proteomic databases
EPDi | D6RB81 |
MaxQBi | D6RB81 |
PeptideAtlasi | D6RB81 |
PRIDEi | D6RB81 |
ProteomicsDBi | 13555 |
Expressioni
Gene expression databases
Bgeei | ENSG00000242110, Expressed in adult mammalian kidney and 121 other tissues |
ExpressionAtlasi | D6RB81, baseline and differential |
Family & Domainsi
Sequence similaritiesi
Belongs to the CoA-transferase III family.ARBA annotation
Phylogenomic databases
GeneTreei | ENSGT00940000157215 |
HOGENOMi | CLU_033975_5_0_1 |
Family and domain databases
Gene3Di | 3.40.50.10540, 1 hit |
InterProi | View protein in InterPro IPR003673, CoA-Trfase_fam_III IPR023606, CoA-Trfase_III_dom_sf |
Pfami | View protein in Pfam PF02515, CoA_transf_3, 1 hit |
SUPFAMi | SSF89796, SSF89796, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
D6RB81-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MALQGISVVE LSGLAPGPFC AMVLADFGAR VVRVDRPGSR YDVSRLGRGK
60 70 80 90 100
RSLVLDLKQP RGAAVLRRLC KRSDVLLEPF RRGVMEKLQL GPEILQRENP
110 120 130 140 150
RLIYARLSGF GQSGSFCRLA GHDINYLALS GVLSKIGRSG ENPYAPLNLL
160 170 180 190 200
ADFAGGGLMC ALGIIMALFD RTRTGKGQVI DANMKLSLWE APRGQNMLDG
210 220 230 240 250
GAPFYTTYRT ADGEFMAVGA IEPQFYELLI KGLGLKSDEL PNQMSMDDWP
260 270 280 290 300
EMKKKFADVF AEKTKAEWCQ IFDGTDACVT PVLTFEEVVH HDHNKERGSF
310 320 330 340 350
ITSEEQDVSP RPAPLLLNTP AIPSFKRDPF IGEHTEEILE EFGFSREEIY
360
QLNSDKIIES NKVKASL
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9UHK6 | AMACR_HUMAN | Alpha-methylacyl-CoA racemase | AMACR | 382 | Annotation score: | ||
V9GYU9 | V9GYU9_HUMAN | Alpha-methylacyl-CoA racemase | AMACR | 281 | Annotation score: | ||
V9GZ45 | V9GZ45_HUMAN | Alpha-methylacyl-CoA racemase | AMACR | 260 | Annotation score: | ||
V9GYP4 | V9GYP4_HUMAN | Alpha-methylacyl-CoA racemase | AMACR | 288 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC139783 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000502637; ENSP00000424351; ENSG00000242110 |
UCSCi | uc063cvh.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC139783 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | D6RB81, 1 interactor |
Chemistry databases
DrugBanki | DB09213, Dexibuprofen DB01050, Ibuprofen |
Proteomic databases
EPDi | D6RB81 |
MaxQBi | D6RB81 |
PeptideAtlasi | D6RB81 |
PRIDEi | D6RB81 |
ProteomicsDBi | 13555 |
Protocols and materials databases
Antibodypediai | 34888, 927 antibodies |
Genome annotation databases
Ensembli | ENST00000502637; ENSP00000424351; ENSG00000242110 |
UCSCi | uc063cvh.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000242110.7 |
HGNCi | HGNC:451, AMACR |
OpenTargetsi | ENSG00000242110 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000157215 |
HOGENOMi | CLU_033975_5_0_1 |
Gene expression databases
Bgeei | ENSG00000242110, Expressed in adult mammalian kidney and 121 other tissues |
ExpressionAtlasi | D6RB81, baseline and differential |
Family and domain databases
Gene3Di | 3.40.50.10540, 1 hit |
InterProi | View protein in InterPro IPR003673, CoA-Trfase_fam_III IPR023606, CoA-Trfase_III_dom_sf |
Pfami | View protein in Pfam PF02515, CoA_transf_3, 1 hit |
SUPFAMi | SSF89796, SSF89796, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D6RB81_HUMAN | |
Accessioni | D6RB81Primary (citable) accession number: D6RB81 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 13, 2010 |
Last sequence update: | July 13, 2010 | |
Last modified: | August 12, 2020 | |
This is version 69 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |