UniProtKB - D6RB41 (D6RB41_HUMAN)
Protein
Submitted name:
Neuronal membrane glycoprotein M6-a
Gene
GPM6A
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Neuronal membrane glycoprotein M6-aImported |
Gene namesi | Name:GPM6AImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:4460, GPM6A |
VEuPathDBi | HostDB:ENSG00000150625.16 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 20 – 42 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 63 – 86 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000150625, Expressed in occipital lobe and 211 other tissues |
ExpressionAtlasi | D6RB41, baseline and differential |
Family & Domainsi
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
GeneTreei | ENSGT00390000006915 |
HOGENOMi | CLU_182650_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR001614, Myelin_PLP |
PANTHERi | PTHR11683, PTHR11683, 1 hit |
Pfami | View protein in Pfam PF01275, Myelin_PLP, 1 hit |
PRINTSi | PR00214, MYELINPLP |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 14 potential isoforms that are computationally mapped.Show allAlign All
D6RB41-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MARTAGDTLD VFTMIDIFKY VIYGIAAAFF VYGILLMVEG FFTTGAIKDL
60 70 80
YGDFKITTCG RCFIMLTYLF MLAWLGVTAF TSLPVYM
Computationally mapped potential isoform sequencesi
There are 14 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP51674 | GPM6A_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A M6A | 278 | Annotation score: | ||
D6R9D2 | D6R9D2_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 218 | Annotation score: | ||
D6R9T7 | D6R9T7_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 129 | Annotation score: | ||
D6RD71 | D6RD71_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 66 | Annotation score: | ||
D6RAE4 | D6RAE4_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 49 | Annotation score: | ||
D6RBM6 | D6RBM6_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 105 | Annotation score: | ||
D6RDV7 | D6RDV7_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 119 | Annotation score: | ||
D6RBH3 | D6RBH3_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 82 | Annotation score: | ||
D6RD95 | D6RD95_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 89 | Annotation score: | ||
D6REJ8 | D6REJ8_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 117 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 87 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC093819 Genomic DNA No translation available. AC097537 Genomic DNA No translation available. AC110794 Genomic DNA No translation available. KF457835 Genomic DNA No translation available. KF457837 Genomic DNA No translation available. KF457840 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000512509; ENSP00000424443; ENSG00000150625 |
UCSCi | uc063bcs.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC093819 Genomic DNA No translation available. AC097537 Genomic DNA No translation available. AC110794 Genomic DNA No translation available. KF457835 Genomic DNA No translation available. KF457837 Genomic DNA No translation available. KF457840 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | D6RB41 |
PRIDEi | D6RB41 |
ProteomicsDBi | 13520 |
Protocols and materials databases
Antibodypediai | 17235, 295 antibodies |
Genome annotation databases
Ensembli | ENST00000512509; ENSP00000424443; ENSG00000150625 |
UCSCi | uc063bcs.1, human |
Organism-specific databases
HGNCi | HGNC:4460, GPM6A |
OpenTargetsi | ENSG00000150625 |
VEuPathDBi | HostDB:ENSG00000150625.16 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000006915 |
HOGENOMi | CLU_182650_0_0_1 |
Miscellaneous databases
ChiTaRSi | GPM6A, human |
Gene expression databases
Bgeei | ENSG00000150625, Expressed in occipital lobe and 211 other tissues |
ExpressionAtlasi | D6RB41, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR001614, Myelin_PLP |
PANTHERi | PTHR11683, PTHR11683, 1 hit |
Pfami | View protein in Pfam PF01275, Myelin_PLP, 1 hit |
PRINTSi | PR00214, MYELINPLP |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D6RB41_HUMAN | |
Accessioni | D6RB41Primary (citable) accession number: D6RB41 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 13, 2010 |
Last sequence update: | July 13, 2010 | |
Last modified: | February 10, 2021 | |
This is version 49 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |