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Protein
Submitted name:

Docking protein 3

Gene

DOK3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Docking protein 3Imported
Gene namesi
Name:DOK3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000146094.13
HGNCiHGNC:24583 DOK3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000146094

PTM / Processingi

Proteomic databases

EPDiD6RAM3
PRIDEiD6RAM3

Expressioni

Gene expression databases

BgeeiENSG00000146094 Expressed in 138 organ(s), highest expression level in blood
ExpressionAtlasiD6RAM3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD6RAM3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini157 – 261IRS-type PTBInterPro annotationAdd BLAST105

Phylogenomic databases

eggNOGiKOG4047 Eukaryota
ENOG410XS2S LUCA
GeneTreeiENSGT00730000110348
HOGENOMiHOG000112245

Family and domain databases

CDDicd01203 PTB_DOK1_DOK2_DOK3, 1 hit
Gene3Di2.30.29.30, 2 hits
InterProiView protein in InterPro
IPR037751 Dok1/2/3_PTB
IPR002404 IRS_PTB
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PfamiView protein in Pfam
PF02174 IRS, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00310 PTBI, 1 hit
PROSITEiView protein in PROSITE
PS51064 IRS_PTB, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

D6RAM3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDPLETPIKD GILYQQHVKF GKKCWRKVWA LLYAGGPSGV ARLESWEVRD
60 70 80 90 100
GGLGAAGDRS AGPGRRGERR VIRLADCVSV LPADGESCPR DTGAFLLTTT
110 120 130 140 150
ERSHLLAAQH RQAWMGPICQ LAFPGTGEAS SGSTDAQSPK RGLVPMEENS
160 170 180 190 200
IYSSWQEVGE FPVVVQRTEA ATRCQLKGPA LLVLGPDAIQ LREAKGTQAL
210 220 230 240 250
YSWPYHFLRK FGSDKGVFSF EAGRRCHSGE GLFAFSTPCA PDLCRAVAGA
260 270 280 290 300
IARQRERLPE LTRPQPCPLP RATSLPSLDT PGELREMPPG PEPPTSRKMH
310 320 330 340 350
LAEPGPQSLP LLLGPEPNDL ASGLYASVCK RASGPPGNEH LYENLCVLEA
360 370 380 390 400
SPTLHGGEPE PHEGPGSRSP TTSPIYHNGQ DLSWPGPAND STLEAQYRRL
410 420 430 440
LELDQVEGTG RPDPQAGFKA KLVTLLSRER RKGPAPCDRP
Length:440
Mass (Da):47,602
Last modified:July 13, 2010 - v1
Checksum:i6A347AB6C78C51E0
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q7L591DOK3_HUMAN
Docking protein 3
DOK3
496Annotation score:
D6RC22D6RC22_HUMAN
Docking protein 3
DOK3
213Annotation score:
D6R977D6R977_HUMAN
Docking protein 3
DOK3
156Annotation score:
D6R951D6R951_HUMAN
Docking protein 3
DOK3
144Annotation score:
D6RAZ9D6RAZ9_HUMAN
Docking protein 3
DOK3
43Annotation score:
D6RF29D6RF29_HUMAN
Docking protein 3
DOK3
13Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC145098 Genomic DNA No translation available.
RefSeqiNP_001295164.1, NM_001308235.1
NP_001295165.1, NM_001308236.1
XP_005266042.1, XM_005265985.3
XP_011532956.1, XM_011534654.2
XP_011532957.1, XM_011534655.2
XP_011532958.1, XM_011534656.2
UniGeneiHs.720849

Genome annotation databases

EnsembliENST00000501403; ENSP00000421688; ENSG00000146094
ENST00000510898; ENSP00000424726; ENSG00000146094
GeneIDi79930
UCSCiuc063kfh.1 human
uc063kfl.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC145098 Genomic DNA No translation available.
RefSeqiNP_001295164.1, NM_001308235.1
NP_001295165.1, NM_001308236.1
XP_005266042.1, XM_005265985.3
XP_011532956.1, XM_011534654.2
XP_011532957.1, XM_011534655.2
XP_011532958.1, XM_011534656.2
UniGeneiHs.720849

3D structure databases

ProteinModelPortaliD6RAM3
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiD6RAM3
PRIDEiD6RAM3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000501403; ENSP00000421688; ENSG00000146094
ENST00000510898; ENSP00000424726; ENSG00000146094
GeneIDi79930
UCSCiuc063kfh.1 human
uc063kfl.1 human

Organism-specific databases

CTDi79930
EuPathDBiHostDB:ENSG00000146094.13
HGNCiHGNC:24583 DOK3
OpenTargetsiENSG00000146094
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4047 Eukaryota
ENOG410XS2S LUCA
GeneTreeiENSGT00730000110348
HOGENOMiHOG000112245

Miscellaneous databases

ChiTaRSiDOK3 human
GenomeRNAii79930

Gene expression databases

BgeeiENSG00000146094 Expressed in 138 organ(s), highest expression level in blood
ExpressionAtlasiD6RAM3 baseline and differential

Family and domain databases

CDDicd01203 PTB_DOK1_DOK2_DOK3, 1 hit
Gene3Di2.30.29.30, 2 hits
InterProiView protein in InterPro
IPR037751 Dok1/2/3_PTB
IPR002404 IRS_PTB
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PfamiView protein in Pfam
PF02174 IRS, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00310 PTBI, 1 hit
PROSITEiView protein in PROSITE
PS51064 IRS_PTB, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD6RAM3_HUMAN
AccessioniPrimary (citable) accession number: D6RAM3
Secondary accession number(s): D6RAV2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: October 10, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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