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Protein
Submitted name:

Amyloid-beta A4 precursor protein-binding family B member 2

Gene

APBB2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Amyloid-beta A4 precursor protein-binding family B member 2Imported
Gene namesi
Name:APBB2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000163697.16
HGNCiHGNC:582 APBB2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000163697

PTM / Processingi

Proteomic databases

MaxQBiD6RAJ4
PeptideAtlasiD6RAJ4
PRIDEiD6RAJ4

Expressioni

Gene expression databases

BgeeiENSG00000163697 Expressed in 227 organ(s), highest expression level in amniotic fluid
ExpressionAtlasiD6RAJ4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD6RAJ4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IEKA Eukaryota
ENOG410YEVS LUCA
GeneTreeiENSGT00390000000002

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR039576 Fe65
IPR011993 PH-like_dom_sf
PANTHERiPTHR14058 PTHR14058, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 13 potential isoforms that are computationally mapped.Show allAlign All

D6RAJ4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAERKNAKAL ACSSLQERAN VNLDVPLQVD FPTPKTELVQ KFHVQYLGML
60 70 80 90
PVDKPVGMDI LNSAIENLMT SSNKEDWLSV NMNVADATVT VISEK
Length:95
Mass (Da):10,503
Last modified:July 13, 2010 - v1
Checksum:i4954F18ED267ED94
GO

Computationally mapped potential isoform sequencesi

There are 13 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q92870APBB2_HUMAN
Amyloid-beta A4 precursor protein-b...
APBB2 FE65L, FE65L1
758Annotation score:
G5E9Y1G5E9Y1_HUMAN
Amyloid beta (A4) protein-binding, ...
APBB2 hCG_33089
737Annotation score:
H0YAJ5H0YAJ5_HUMAN
Amyloid-beta A4 precursor protein-b...
APBB2
728Annotation score:
H0Y9U9H0Y9U9_HUMAN
Amyloid-beta A4 precursor protein-b...
APBB2
142Annotation score:
D6RD19D6RD19_HUMAN
Amyloid-beta A4 precursor protein-b...
APBB2
102Annotation score:
H0YA92H0YA92_HUMAN
Amyloid-beta A4 precursor protein-b...
APBB2
179Annotation score:
D6RGD4D6RGD4_HUMAN
Amyloid-beta A4 precursor protein-b...
APBB2
87Annotation score:
D6RB55D6RB55_HUMAN
Amyloid-beta A4 precursor protein-b...
APBB2
140Annotation score:
D6RB00D6RB00_HUMAN
Amyloid-beta A4 precursor protein-b...
APBB2
68Annotation score:
D6RDY3D6RDY3_HUMAN
Amyloid-beta A4 precursor protein-b...
APBB2
26Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei95Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093804 Genomic DNA No translation available.
AC096712 Genomic DNA No translation available.
AC108937 Genomic DNA No translation available.
AC131953 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000514920; ENSP00000421751; ENSG00000163697
UCSCiuc062weh.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093804 Genomic DNA No translation available.
AC096712 Genomic DNA No translation available.
AC108937 Genomic DNA No translation available.
AC131953 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliD6RAJ4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiD6RAJ4
PeptideAtlasiD6RAJ4
PRIDEiD6RAJ4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000514920; ENSP00000421751; ENSG00000163697
UCSCiuc062weh.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000163697.16
HGNCiHGNC:582 APBB2
OpenTargetsiENSG00000163697
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IEKA Eukaryota
ENOG410YEVS LUCA
GeneTreeiENSGT00390000000002

Miscellaneous databases

ChiTaRSiAPBB2 human

Gene expression databases

BgeeiENSG00000163697 Expressed in 227 organ(s), highest expression level in amniotic fluid
ExpressionAtlasiD6RAJ4 baseline and differential

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR039576 Fe65
IPR011993 PH-like_dom_sf
PANTHERiPTHR14058 PTHR14058, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD6RAJ4_HUMAN
AccessioniPrimary (citable) accession number: D6RAJ4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: November 7, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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