UniProtKB - D6R9T7 (D6R9T7_HUMAN)
Protein
Submitted name:
Neuronal membrane glycoprotein M6-a
Gene
GPM6A
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Neuronal membrane glycoprotein M6-aImported |
Gene namesi | Name:GPM6AImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:4460, GPM6A |
VEuPathDBi | HostDB:ENSG00000150625.16 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 21 – 43 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 80 – 101 | HelicalSequence analysisAdd BLAST | 22 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000150625, Expressed in occipital lobe and 211 other tissues |
ExpressionAtlasi | D6R9T7, baseline and differential |
Family & Domainsi
Sequence similaritiesi
Belongs to the myelin proteolipid protein family.ARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00390000006915 |
HOGENOMi | CLU_2151397_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR001614, Myelin_PLP IPR018237, Myelin_PLP_CS |
PANTHERi | PTHR11683, PTHR11683, 1 hit |
Pfami | View protein in Pfam PF01275, Myelin_PLP, 1 hit |
PRINTSi | PR00214, MYELINPLP |
PROSITEi | View protein in PROSITE PS00575, MYELIN_PLP_1, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 14 potential isoforms that are computationally mapped.Show allAlign All
D6R9T7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEENMEEGQT QKGCFECCIK CLGGIPYASL IATILLYAGV ALFCGCGHEA
60 70 80 90 100
LSGTVNILQT YFEMARTAGD TLDVFTMIDI FKYVIYGIAA AFFVYGILLM
110 120
VEGFFTTGAI KDLYGDFKIT TCGRCVSAW
Computationally mapped potential isoform sequencesi
There are 14 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP51674 | GPM6A_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A M6A | 278 | Annotation score: | ||
D6R9D2 | D6R9D2_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 218 | Annotation score: | ||
D6RD71 | D6RD71_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 66 | Annotation score: | ||
D6RB41 | D6RB41_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 87 | Annotation score: | ||
D6RAE4 | D6RAE4_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 49 | Annotation score: | ||
D6RBM6 | D6RBM6_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 105 | Annotation score: | ||
D6RDV7 | D6RDV7_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 119 | Annotation score: | ||
D6RBH3 | D6RBH3_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 82 | Annotation score: | ||
D6RD95 | D6RD95_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 89 | Annotation score: | ||
D6REJ8 | D6REJ8_HUMAN | Neuronal membrane glycoprotein M6-a | GPM6A | 117 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 129 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC093819 Genomic DNA No translation available. AC097537 Genomic DNA No translation available. AC110794 Genomic DNA No translation available. KF457835 Genomic DNA No translation available. KF457837 Genomic DNA No translation available. KF457840 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000513365; ENSP00000423122; ENSG00000150625 |
UCSCi | uc063bcv.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC093819 Genomic DNA No translation available. AC097537 Genomic DNA No translation available. AC110794 Genomic DNA No translation available. KF457835 Genomic DNA No translation available. KF457837 Genomic DNA No translation available. KF457840 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | D6R9T7 |
ProteomicsDBi | 13115 |
Protocols and materials databases
Antibodypediai | 17235, 303 antibodies |
Genome annotation databases
Ensembli | ENST00000513365; ENSP00000423122; ENSG00000150625 |
UCSCi | uc063bcv.1, human |
Organism-specific databases
HGNCi | HGNC:4460, GPM6A |
OpenTargetsi | ENSG00000150625 |
VEuPathDBi | HostDB:ENSG00000150625.16 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000006915 |
HOGENOMi | CLU_2151397_0_0_1 |
Miscellaneous databases
ChiTaRSi | GPM6A, human |
Gene expression databases
Bgeei | ENSG00000150625, Expressed in occipital lobe and 211 other tissues |
ExpressionAtlasi | D6R9T7, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR001614, Myelin_PLP IPR018237, Myelin_PLP_CS |
PANTHERi | PTHR11683, PTHR11683, 1 hit |
Pfami | View protein in Pfam PF01275, Myelin_PLP, 1 hit |
PRINTSi | PR00214, MYELINPLP |
PROSITEi | View protein in PROSITE PS00575, MYELIN_PLP_1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D6R9T7_HUMAN | |
Accessioni | D6R9T7Primary (citable) accession number: D6R9T7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 13, 2010 |
Last sequence update: | July 13, 2010 | |
Last modified: | April 7, 2021 | |
This is version 69 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |