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UniProtKB - D6R978 (D6R978_HUMAN)
Protein
Submitted name:
cGMP-gated cation channel alpha-1
Gene
CNGA1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- intracellular cyclic nucleotide activated cation channel activity Source: InterPro
GO - Biological processi
- visual perception Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: cGMP-gated cation channel alpha-1 |
Gene namesi | Name:CNGA1 |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:2148, CNGA1 |
VEuPathDBi | HostDB:ENSG00000198515 |
Expressioni
Gene expression databases
Bgeei | ENSG00000198515, Expressed in amniotic fluid and 135 other tissues |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 31 – 79 | DisorderedSequence analysisAdd BLAST | 49 |
Phylogenomic databases
GeneTreei | ENSGT00940000156074 |
OMAi | IEFEGRH |
Family and domain databases
InterProi | View protein in InterPro IPR032945, CNGA1 |
PANTHERi | PTHR45638:SF9, PTHR45638:SF9, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
D6R978-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKNNIINTQQ SFVTMPNVIV PDIEKEIRRM ENGACSSFSE DDDSASTSEE
60 70 80 90
SENENPHARG SFSYKSLRKG GPSQREQYLP GAIALFNVNN SSNKD
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP29973 | CNGA1_HUMAN | cGMP-gated cation channel alpha-1 | CNGA1 CNCG, CNCG1 | 686 | Annotation score: | ||
D6RCF1 | D6RCF1_HUMAN | cGMP-gated cation channel alpha-1 | CNGA1 | 124 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 95 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC096749 Genomic DNA No translation available. AC107068 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000513178.2; ENSP00000423327.2; ENSG00000198515.16 ENST00000514520.6; ENSP00000421110.2; ENSG00000198515.16 |
UCSCi | uc062wkh.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC096749 Genomic DNA No translation available. AC107068 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 23791, 101 antibodies from 23 providers |
Genome annotation databases
Ensembli | ENST00000513178.2; ENSP00000423327.2; ENSG00000198515.16 ENST00000514520.6; ENSP00000421110.2; ENSG00000198515.16 |
UCSCi | uc062wkh.1, human |
Organism-specific databases
HGNCi | HGNC:2148, CNGA1 |
OpenTargetsi | ENSG00000198515 |
VEuPathDBi | HostDB:ENSG00000198515 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000156074 |
OMAi | IEFEGRH |
Miscellaneous databases
ChiTaRSi | CNGA1, human |
Gene expression databases
Bgeei | ENSG00000198515, Expressed in amniotic fluid and 135 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR032945, CNGA1 |
PANTHERi | PTHR45638:SF9, PTHR45638:SF9, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | D6R978_HUMAN | |
Accessioni | D6R978Primary (citable) accession number: D6R978 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 13, 2010 |
Last sequence update: | April 7, 2021 | |
Last modified: | May 25, 2022 | |
This is version 73 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |