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Protein
Submitted name:

Cytokine receptor common subunit gamma

Gene

IL2RG

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
Cytokine receptor common subunit gammaImported
Gene namesi
Name:IL2RGImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000147168.12
HGNCiHGNC:6010 IL2RG

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000147168

PTM / Processingi

Proteomic databases

PeptideAtlasiD6R964
PRIDEiD6R964

Expressioni

Gene expression databases

BgeeiENSG00000147168 Expressed in 165 organ(s), highest expression level in leukocyte
ExpressionAtlasiD6R964 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD6R964
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 98IL6Ra-bindInterPro annotationAdd BLAST60

Phylogenomic databases

eggNOGiENOG410IGNI Eukaryota
ENOG4111N9N LUCA
GeneTreeiENSGT00510000048979

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR015321 TypeI_recpt_CBD
PfamiView protein in Pfam
PF09240 IL6Ra-bind, 1 hit
SUPFAMiSSF49265 SSF49265, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

D6R964-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGMKTPQLVG NLGLEGADFF LTTMPTDSLS VSTLPLPEVQ CFVFNVEYMN
60 70 80 90
CTWNSSSEPQ PTNLTLHYWY KNSDNDKVQK CSHYLFSEEI TSGCQLQKK
Length:99
Mass (Da):11,235
Last modified:July 13, 2010 - v1
Checksum:i49D4F6E34CF198C8
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P31785IL2RG_HUMAN
Cytokine receptor common subunit ga...
IL2RG
369Annotation score:
D6RDW9D6RDW9_HUMAN
Cytokine receptor common subunit ga...
IL2RG
219Annotation score:
H0Y8J6H0Y8J6_HUMAN
Cytokine receptor common subunit ga...
IL2RG
65Annotation score:
Q5FC10Q5FC10_HUMAN
Cytokine receptor common subunit ga...
IL2RG
98Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei99Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590764 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000473378; ENSP00000423601; ENSG00000147168
UCSCiuc064ztr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590764 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliD6R964
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiD6R964
PRIDEiD6R964

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000473378; ENSP00000423601; ENSG00000147168
UCSCiuc064ztr.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000147168.12
HGNCiHGNC:6010 IL2RG
OpenTargetsiENSG00000147168
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IGNI Eukaryota
ENOG4111N9N LUCA
GeneTreeiENSGT00510000048979

Miscellaneous databases

ChiTaRSiIL2RG human

Gene expression databases

BgeeiENSG00000147168 Expressed in 165 organ(s), highest expression level in leukocyte
ExpressionAtlasiD6R964 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR015321 TypeI_recpt_CBD
PfamiView protein in Pfam
PF09240 IL6Ra-bind, 1 hit
SUPFAMiSSF49265 SSF49265, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD6R964_HUMAN
AccessioniPrimary (citable) accession number: D6R964
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: September 12, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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