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Protein
Submitted name:

Recombining-binding protein suppressor of hairless

Gene

RBPJ

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Recombining-binding protein suppressor of hairlessImported
Gene namesi
Name:RBPJImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000168214.20
HGNCiHGNC:5724 RBPJ

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000168214

PTM / Processingi

Proteomic databases

MaxQBiD6R927
PeptideAtlasiD6R927
PRIDEiD6R927

Expressioni

Gene expression databases

BgeeiENSG00000168214 Expressed in 242 organ(s), highest expression level in corpus callosum
ExpressionAtlasiD6R927 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD6R927
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 164LAG1_DNAbindInterPro annotationAdd BLAST132
Domaini165 – 314BTDInterPro annotationAdd BLAST150

Phylogenomic databases

eggNOGiKOG3743 Eukaryota
ENOG410XV7K LUCA
GeneTreeiENSGT00390000005197
HOGENOMiHOG000253907

Family and domain databases

Gene3Di2.60.40.1450, 1 hit
InterProiView protein in InterPro
IPR015350 Beta-trefoil_DNA-bd_dom
IPR036358 BTD_sf
IPR008967 p53-like_TF_DNA-bd
IPR015351 RBP-J/Cbf11/Cbf12_DNA-bd
IPR037095 RBP-J/Cbf11/Cbf12_DNA-bd_sf
PfamiView protein in Pfam
PF09270 BTD, 1 hit
PF09271 LAG1-DNAbind, 1 hit
SMARTiView protein in SMART
SM01268 BTD, 1 hit
SM01267 LAG1_DNAbind, 1 hit
SUPFAMiSSF110217 SSF110217, 1 hit
SSF49417 SSF49417, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 16 potential isoforms that are computationally mapped.Show allAlign All

D6R927-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAWIKRKFGE RPPPKRLTRE AMRNYLKERG DQTVLILHAK VAQKSYGNEK
60 70 80 90 100
RFFCPPPCVY LMGSGWKKKK EQMERDGCSE QESQPCAFIG IGNSDQEMQQ
110 120 130 140 150
LNLEGKNYCT AKTLYISDSD KRKHFMLSVK MFYGNSDDIG VFLSKRIKVI
160 170 180 190 200
SKPSKKKQSL KNADLCIASG TKVALFNRLR SQTVSTRYLH VEGGNFHASS
210 220 230 240 250
QQWGAFFIHL LDDDESEGEE FTVRDGYIHY GQTVKLVCSV TGMALPRLII
260 270 280 290 300
RKVDKQTALL DADDPVSQLH KCAFYLKDTE RMYLCLSQER IIQFQATPCP
310 320 330 340 350
KEPNKEMIND GASWTIISTD KAEYTFYEGM GPVLAPVTPV PVVESLQVWR
360 370 380
EYALCRPRHF CIPRRLEMGP ATSPGSSNFG PK
Length:382
Mass (Da):43,496
Last modified:July 13, 2010 - v1
Checksum:iD7E8E960CA804A62
GO

Computationally mapped potential isoform sequencesi

There are 16 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q06330SUH_HUMAN
Recombining binding protein suppres...
RBPJ IGKJRB, IGKJRB1, RBPJK, RBPSUH
500Annotation score:
D6RA45D6RA45_HUMAN
Recombining-binding protein suppres...
RBPJ
189Annotation score:
D6R946D6R946_HUMAN
Recombining-binding protein suppres...
RBPJ
178Annotation score:
D6RBQ8D6RBQ8_HUMAN
Recombining-binding protein suppres...
RBPJ
157Annotation score:
D6RB37D6RB37_HUMAN
Recombining-binding protein suppres...
RBPJ
143Annotation score:
D6RAT2D6RAT2_HUMAN
Recombining-binding protein suppres...
RBPJ
94Annotation score:
D6RCM1D6RCM1_HUMAN
Recombining-binding protein suppres...
RBPJ
229Annotation score:
D6REC2D6REC2_HUMAN
Recombining-binding protein suppres...
RBPJ
113Annotation score:
D6RIV8D6RIV8_HUMAN
Recombining-binding protein suppres...
RBPJ
53Annotation score:
D6R9X3D6R9X3_HUMAN
Recombining-binding protein suppres...
RBPJ
107Annotation score:
There are more potential isoformsShow all

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093637 Genomic DNA No translation available.
AC097109 Genomic DNA No translation available.
AC097714 Genomic DNA No translation available.
AC111003 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000504907; ENSP00000423703; ENSG00000168214
UCSCiuc062vtb.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093637 Genomic DNA No translation available.
AC097109 Genomic DNA No translation available.
AC097714 Genomic DNA No translation available.
AC111003 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliD6R927
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiD6R927
PeptideAtlasiD6R927
PRIDEiD6R927

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000504907; ENSP00000423703; ENSG00000168214
UCSCiuc062vtb.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000168214.20
HGNCiHGNC:5724 RBPJ
OpenTargetsiENSG00000168214
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3743 Eukaryota
ENOG410XV7K LUCA
GeneTreeiENSGT00390000005197
HOGENOMiHOG000253907

Miscellaneous databases

ChiTaRSiRBPJ human

Gene expression databases

BgeeiENSG00000168214 Expressed in 242 organ(s), highest expression level in corpus callosum
ExpressionAtlasiD6R927 baseline and differential

Family and domain databases

Gene3Di2.60.40.1450, 1 hit
InterProiView protein in InterPro
IPR015350 Beta-trefoil_DNA-bd_dom
IPR036358 BTD_sf
IPR008967 p53-like_TF_DNA-bd
IPR015351 RBP-J/Cbf11/Cbf12_DNA-bd
IPR037095 RBP-J/Cbf11/Cbf12_DNA-bd_sf
PfamiView protein in Pfam
PF09270 BTD, 1 hit
PF09271 LAG1-DNAbind, 1 hit
SMARTiView protein in SMART
SM01268 BTD, 1 hit
SM01267 LAG1_DNAbind, 1 hit
SUPFAMiSSF110217 SSF110217, 1 hit
SSF49417 SSF49417, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD6R927_HUMAN
AccessioniPrimary (citable) accession number: D6R927
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: November 7, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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