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Protein

Uracil-DNA glycosylase

Gene

ung1

Organism
Streptomyces lividans TK24
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.UniRule annotation

Catalytic activityi

Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei68Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseImported, Hydrolase
Biological processDNA damage, DNA repairUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Uracil-DNA glycosylaseUniRule annotation (EC:3.2.2.27UniRule annotation)
Short name:
UDGUniRule annotation
Gene namesi
Name:ung1Imported
Synonyms:ungUniRule annotation
ORF Names:SLIV_32230Imported
OrganismiStreptomyces lividans TK24Imported
Taxonomic identifieri457428 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000028682 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 212UDGInterPro annotationAdd BLAST160

Sequence similaritiesi

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK03648

Family and domain databases

CDDicd10027 UDG_F1, 1 hit
Gene3Di3.40.470.10, 1 hit
HAMAPiMF_00148 UDG, 1 hit
InterProiView protein in InterPro
IPR002043 UDG_fam1
IPR018085 Ura-DNA_Glyclase_AS
IPR005122 Uracil-DNA_glycosylase-like
IPR036895 Uracil-DNA_glycosylase-like_sf
PANTHERiPTHR11264 PTHR11264, 1 hit
PfamiView protein in Pfam
PF03167 UDG, 1 hit
SMARTiView protein in SMART
SM00986 UDG, 1 hit
SUPFAMiSSF52141 SSF52141, 1 hit
PROSITEiView protein in PROSITE
PS00130 U_DNA_GLYCOSYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

D6ETU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPRPLNEIV EAGWAKALEP VAGQITSMGE FLRAEIAAGR TYLPAGANVL
60 70 80 90 100
RAFQQPFDDV RVLIVGQDPY PTPGHAVGLS FSVAPEVRPL PGSLVNIFRE
110 120 130 140 150
LNTDLNLPQP ANGDLTPWTQ QGVLLLNRAL TTAPRKPAAH RGKGWEEVTE
160 170 180 190 200
QAIRALAARG KPMVSILWGR DARNLRPLLG DLPALESAHP SPMSADRGFF
210 220
GSRPFSRAND LLMRLGGQPV DWRLP
Length:225
Mass (Da):24,428
Last modified:July 13, 2010 - v1
Checksum:i97E35EBD68DDEDB4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009124 Genomic DNA Translation: AIJ17333.1
RefSeqiWP_003977718.1, NZ_GG657756.1

Genome annotation databases

EnsemblBacteriaiAIJ17333; AIJ17333; SLIV_32230
KEGGislv:SLIV_32230
PATRICifig|457428.16.peg.6602

Similar proteinsi

Entry informationi

Entry nameiD6ETU4_STRLI
AccessioniPrimary (citable) accession number: D6ETU4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: May 23, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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