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Protein

Arginine--tRNA ligase

Gene

argS

Organism
[Eubacterium] rectale DSM 17629
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationImported, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
ORF Names:EUR_18070Imported
Organismi[Eubacterium] rectale DSM 17629Imported
Taxonomic identifieri657318 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesLachnospiraceae
Proteomesi
  • UP000007057 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi657318.EUR_18070

Structurei

3D structure databases

ProteinModelPortaliD6E610
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 87Arg_tRNA_synt_NInterPro annotationAdd BLAST86
Domaini477 – 597DALR_1InterPro annotationAdd BLAST121

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili406 – 437Sequence analysisAdd BLAST32

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi124 – 134"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
KOiK01887

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

D6E610-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKKLINLISE EVTKAFVSAG YDEKYGKVTL SNRPDLCEFQ CNGAMAAAKE
60 70 80 90 100
YKCAPFMISD KVAALLESDE MFESVESVKP GFLNIKMDTA FLAKYMNDMK
110 120 130 140 150
DDEGRYGLEK AKKPLTIVVD YGGPNVAKPL HVGHLRSAVI GESVKRIAKF
160 170 180 190 200
MGHNVIGDVH LGDWGLQMGL IITELRERKP DLVYFDESYT GEYPKEAPFT
210 220 230 240 250
ISELEDIYPT ASGKSKSDES FKEAALLATK ELQGGRRGYQ ALLSHIMNVS
260 270 280 290 300
VTDLKRNYEN LNVHFELWKG ESDAQPYVPE MVEMMKEKGF AHMSEGALVV
310 320 330 340 350
DVKEDTDTKE IPPCIILKSD GASLYSTTDL ATLVMRMKEN NPDRVIYLAD
360 370 380 390 400
ARQSMHFIQV FRCARKTGIV PDTTELVHIG FGTMNGKDGK PFKTRDGGVM
410 420 430 440 450
RLEYLLKEID DEMLNKIKEN QKEKENLNID EAEAEQTAKT VALAAVKYGD
460 470 480 490 500
LSNQASKDYI FDIDRFTSFE GNTGPYILYT IVRIKSILSK YEAKGGDISA
510 520 530 540 550
LKDAIMPAVN AGQKNLMLSL AKFNATIESA YEESAPHKIC AYIYELANAF
560 570 580 590
NGFYHDTKIL SEENEELKKS YISLLVLTKE ILEACIDMLG FSAPDRM
Length:597
Mass (Da):66,817
Last modified:July 13, 2010 - v1
Checksum:iC0606C551801DDB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP929042 Genomic DNA Translation: CBK90850.1

Genome annotation databases

EnsemblBacteriaiCBK90850; CBK90850; EUR_18070
KEGGiert:EUR_18070
PATRICifig|657318.4.peg.1622

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP929042 Genomic DNA Translation: CBK90850.1

3D structure databases

ProteinModelPortaliD6E610
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi657318.EUR_18070

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBK90850; CBK90850; EUR_18070
KEGGiert:EUR_18070
PATRICifig|657318.4.peg.1622

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
KOiK01887

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD6E610_9FIRM
AccessioniPrimary (citable) accession number: D6E610
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: March 28, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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