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Protein

Conotoxin Cl6.9

Gene
N/A
Organism
Californiconus californicus (California cone) (Conus californicus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionNeurotoxin, Toxin

Names & Taxonomyi

Protein namesi
Recommended name:
Conotoxin Cl6.9
OrganismiCaliforniconus californicus (California cone) (Conus californicus)
Taxonomic identifieri1736779 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaHypsogastropodaNeogastropodaConoideaConidaeCaliforniconus

Organism-specific databases

ConoServeri4043 Cl6.9 precursor

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
PropeptideiPRO_000041498925 – 37By similarityAdd BLAST13
PeptideiPRO_000041499040 – 67Conotoxin Cl6.9Add BLAST28

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi43 ↔ 57By similarity
Disulfide bondi50 ↔ 61By similarity
Disulfide bondi56 ↔ 65By similarity

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom duct.

Family & Domainsi

Domaini

The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.By similarity
The cysteine framework is VI/VII (C-C-CC-C-C).

Sequence similaritiesi

Belongs to the conotoxin O1 superfamily.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR004214 Conotoxin
PfamiView protein in Pfam
PF02950 Conotoxin, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

D6C4L7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLTCVLIAA VLPLAVCQFD STDASAYMRK NPSLRSPKRT RDCKTKGSVC
60
FASSECCIQD CWFVCLY
Length:67
Mass (Da):7,475
Last modified:July 13, 2010 - v1
Checksum:i3D57CAC4FE0C5D49
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ959159 Genomic DNA Translation: ADB93129.1

Similar proteinsi

Entry informationi

Entry nameiCM69_CONCL
AccessioniPrimary (citable) accession number: D6C4L7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 25, 2012
Last sequence update: July 13, 2010
Last modified: November 22, 2017
This is version 14 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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