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Protein

Conotoxin Cl14.8

Gene
N/A
Organism
Californiconus californicus (California cone) (Conus californicus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionNeurotoxin, Toxin

Names & Taxonomyi

Protein namesi
Recommended name:
Conotoxin Cl14.8
OrganismiCaliforniconus californicus (California cone) (Conus californicus)
Taxonomic identifieri1736779 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaNeogastropodaConoideaConidaeCaliforniconus

Organism-specific databases

ConoServeri4024 Cl14.8 precursor

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
PropeptideiPRO_000041502620 – 47By similarityAdd BLAST28
PeptideiPRO_000041502750 – 73Conotoxin Cl14.8Add BLAST24

Post-translational modificationi

Contains 2 disulfide bonds.By similarity

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom duct.

Family & Domainsi

Domaini

The cysteine framework is XIV (C-C-C-C).

Sequence similaritiesi

Belongs to the conotoxin L superfamily.Curated

Keywords - Domaini

Signal

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

D6C4J7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKLSVTFIAL MLTMTLTQGF VLQAIDGRDN SGLDDLSEAD SMEHQLQRRD
60 70
CGRCPLGQYC DAEAGMCKPT LIM
Length:73
Mass (Da):8,056
Last modified:July 13, 2010 - v1
Checksum:i9E7CD49F2CC7E9A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ959139 Genomic DNA Translation: ADB93109.1

Entry informationi

Entry nameiCLE8_CONCL
AccessioniPrimary (citable) accession number: D6C4J7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 25, 2012
Last sequence update: July 13, 2010
Last modified: September 12, 2018
This is version 13 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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