Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 64 (07 Oct 2020)
Sequence version 1 (13 Jul 2010)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Succinate dehydrogenase flavoprotein subunit

Gene

EQK42_23540

Organism
Streptomyces albidoflavus
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

FADUniRule annotationARBA annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes fumarate from succinate (bacterial route).UniRule annotationARBA annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Succinate dehydrogenase flavoprotein subunit (EQK42_23540), Succinate dehydrogenase flavoprotein subunit (CLM82_02745), Succinate dehydrogenase flavoprotein subunit (FE156_19895)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes fumarate from succinate (bacterial route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductaseUniRule annotationImportedARBA annotation
Biological processElectron transportUniRule annotationARBA annotation, Transport, Tricarboxylic acid cycleUniRule annotationARBA annotation
LigandFADUniRule annotation, Flavoprotein

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00223;UER01005

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Succinate dehydrogenase flavoprotein subunitUniRule annotationARBA annotation (EC:1.3.5.1UniRule annotationARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:EQK42_23540Imported, FRZ02_25700Imported, G3I57_17910Imported, Salbus254_4155Imported, SSHG_02000Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStreptomyces albidoflavusImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1886 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005105 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000070561 Componenti: Chromosome
  • UP000287551 Componenti: Unassembled WGS sequence
  • UP000483624 Componenti: Unassembled WGS sequence
  • UP000318052 Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

MembraneUniRule annotationARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
457425.XNR_3934

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini7 – 400FAD_binding_2InterPro annotationAdd BLAST394
Domaini454 – 584Succ_DH_flav_CInterPro annotationAdd BLAST131

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili474 – 494Sequence analysisAdd BLAST21

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.UniRule annotationARBA annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG1053, Bacteria

KEGG Orthology (KO)

More...
KOi
K00239

Database of Orthologous Groups

More...
OrthoDBi
153138at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.50.50.60, 1 hit
3.90.700.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003953, FAD-binding_2
IPR036188, FAD/NAD-bd_sf
IPR003952, FRD_SDH_FAD_BS
IPR037099, Fum_R/Succ_DH_flav-like_C_sf
IPR015939, Fum_Rdtase/Succ_DH_flav-like_C
IPR027477, Succ_DH/fumarate_Rdtase_cat_sf
IPR011281, Succ_DH_flav_su_fwd
IPR014006, Succ_Dhase_FrdA_Gneg

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00890, FAD_binding_2, 1 hit
PF02910, Succ_DH_flav_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46977, SSF46977, 1 hit
SSF51905, SSF51905, 1 hit
SSF56425, SSF56425, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01816, sdhA_forward, 1 hit
TIGR01812, sdhA_frdA_Gneg, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00504, FRD_SDH_FAD_BINDING, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D6B3C1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKIHKYDTVI VGAGGAGMRA AIEATKRSRT AVLTKLYPTR SHTGAAQGGM
60 70 80 90 100
AAALANVEDD NWEWHTFDTV KGGDYLVDQD AAEILAKEAI DAVLDLEKMG
110 120 130 140 150
LPFNRTPEGR IDQRRFGGHT RSHGEAPVRR ACYAADRTGH MILQTLYQNC
160 170 180 190 200
VKEGVEFFNE FYVLDQLITE VDGVKKSAGV VAYELATGEI HVFQAKSVVY
210 220 230 240 250
ASGGTGKFFK VTSNAHTLTG DGQAACFRRG LPLEDMEFFQ FHPTGIWRMG
260 270 280 290 300
ILLTEGARGE GGILRNKDGE RFMEKYAPVM KDLASRDVVS RSIYTEIREG
310 320 330 340 350
RGCGPEGDHV FLDLTHLPPE QLDAKLPDIT EFARTYLGIE PYTDPIPIQP
360 370 380 390 400
TAHYAMGGIP TNVQGEVLAD NTTVVPGLYA AGEVACVSVH GANRLGTNSL
410 420 430 440 450
LDINVFGRRA GIAAAEYSHG NDYVELPEDP AAQVIEMVER LRDSNGTERV
460 470 480 490 500
TELRTELQET MDANVMVFRT EQTIKTAVDK IAELRARYKN VSVQDKGRRF
510 520 530 540 550
NTDLLEAIEL GNLLDLAEVM AQSALARKES RGGHYREDFP NRDDVNFMRH
560 570 580
TMAYREVGDD GQESIRLDYK PVVQTRYQPM ERKY
Length:584
Mass (Da):64,810
Last modified:July 13, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD35F11F4BFE2787C
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP014485 Genomic DNA Translation: AMM10618.1
DS999645 Genomic DNA Translation: EFE81558.2
JAAGNK010000345 Genomic DNA Translation: NEC97175.1
SCDQ01000379 Genomic DNA Translation: RWZ73598.1
VOGX01000054 Genomic DNA Translation: TWV19654.1

NCBI Reference Sequences

More...
RefSeqi
WP_003948438.1, NZ_VOGX01000054.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AMM10618; AMM10618; Salbus254_4155
EFE81558; EFE81558; SSHG_02000

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
31253038

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
salb:XNR_3934

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1888.8.peg.4267
fig|457425.27.peg.4062

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP014485 Genomic DNA Translation: AMM10618.1
DS999645 Genomic DNA Translation: EFE81558.2
JAAGNK010000345 Genomic DNA Translation: NEC97175.1
SCDQ01000379 Genomic DNA Translation: RWZ73598.1
VOGX01000054 Genomic DNA Translation: TWV19654.1
RefSeqiWP_003948438.1, NZ_VOGX01000054.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi457425.XNR_3934

Genome annotation databases

EnsemblBacteriaiAMM10618; AMM10618; Salbus254_4155
EFE81558; EFE81558; SSHG_02000
GeneIDi31253038
KEGGisalb:XNR_3934
PATRICifig|1888.8.peg.4267
fig|457425.27.peg.4062

Phylogenomic databases

eggNOGiCOG1053, Bacteria
KOiK00239
OrthoDBi153138at2

Enzyme and pathway databases

UniPathwayiUPA00223;UER01005

Family and domain databases

Gene3Di3.50.50.60, 1 hit
3.90.700.10, 1 hit
InterProiView protein in InterPro
IPR003953, FAD-binding_2
IPR036188, FAD/NAD-bd_sf
IPR003952, FRD_SDH_FAD_BS
IPR037099, Fum_R/Succ_DH_flav-like_C_sf
IPR015939, Fum_Rdtase/Succ_DH_flav-like_C
IPR027477, Succ_DH/fumarate_Rdtase_cat_sf
IPR011281, Succ_DH_flav_su_fwd
IPR014006, Succ_Dhase_FrdA_Gneg
PfamiView protein in Pfam
PF00890, FAD_binding_2, 1 hit
PF02910, Succ_DH_flav_C, 1 hit
SUPFAMiSSF46977, SSF46977, 1 hit
SSF51905, SSF51905, 1 hit
SSF56425, SSF56425, 1 hit
TIGRFAMsiTIGR01816, sdhA_forward, 1 hit
TIGR01812, sdhA_frdA_Gneg, 1 hit
PROSITEiView protein in PROSITE
PS00504, FRD_SDH_FAD_BINDING, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD6B3C1_9ACTN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D6B3C1
Secondary accession number(s): A0A0X3WL30, A0A126Y6L7, A0A2M9SGE1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: October 7, 2020
This is version 64 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again