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Entry version 54 (11 Dec 2019)
Sequence version 1 (13 Jul 2010)
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Protein
Submitted name:

Transcriptional activator protein

Gene

SSHG_03895

Organism
Streptomyces albidoflavus
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi1 – 94OmpR/PhoB-typePROSITE-ProRule annotationAdd BLAST94

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Transcriptional activator proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:SSHG_03895Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStreptomyces albidoflavusImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1886 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005105 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
457425.XNR_2036

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 94OmpR/PhoB-typeInterPro annotationAdd BLAST94
Domaini956 – 1082YcaOInterPro annotationAdd BLAST127

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni248 – 274DisorderedSequence analysisAdd BLAST27

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4106NCY Bacteria
COG3629 LUCA

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.10, 1 hit
1.25.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR041664 AAA_16
IPR022291 Bacteriocin_synth_cyclodeHase
IPR005158 BTAD
IPR001867 OmpR/PhoB-type_DNA-bd
IPR027417 P-loop_NTPase
IPR016032 Sig_transdc_resp-reg_C-effctor
IPR011990 TPR-like_helical_dom_sf
IPR036388 WH-like_DNA-bd_sf
IPR003776 YcaO-like_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13191 AAA_16, 1 hit
PF03704 BTAD, 1 hit
PF00486 Trans_reg_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 1 hit
SM01043 BTAD, 1 hit
SM00862 Trans_reg_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46894 SSF46894, 1 hit
SSF48452 SSF48452, 1 hit
SSF52540 SSF52540, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03882 cyclo_dehyd_2, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51755 OMPR_PHOB, 1 hit
PS51664 YCAO, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

D6B2R9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRFQLLGPLS LHDGPESVVL QPAKPTVLLT ALLLHANSVV SADYLQRAIW
60 70 80 90 100
GEEQPATAKA ALQTCVLRLR RLFTKHGVTE TPIEAVPGGY RITAGPHTLD
110 120 130 140 150
LIGFRERVRR AAALTHDPQA ELAALRDALA LWQGPLLANV RSDLLHRDEV
160 170 180 190 200
PRLAEERLRA VERLCGLHLR LGRCGEALGD LWEVTRAHPG HERFHEQLVE
210 220 230 240 250
ALYRTGRQAE ALAEYRRVKE YLLQELGVDP GAALQRLELA ILRGDTLDAG
260 270 280 290 300
PAGEEDGRPA ALPEAPAAPG PEEPGLVTAL TPVPDFTGRA AEVAALTSHL
310 320 330 340 350
TADTAHRPGG PLTVVLSGAP GIGKSALARH VATQLADRFP GGRLLIRLTG
360 370 380 390 400
PDGRPHDPQT VAGQLTRALA DRPPGSPTLL VLDDAAGADQ VRPLLAACTG
410 420 430 440 450
GAVVVTSRRG LAGLVATHGG RVVRLGPFRP AESHALLRSV LGAERVDAEP
460 470 480 490 500
DEARRIAEGC GHHPLALRIM TARLLTRPGL GLADSARWLG PDQAGRLALT
510 520 530 540 550
DAPGLSVPEV LGEALARLDP PLADAFPRVA ALGPACGAEE VFTQTPGGVL
560 570 580 590 600
FHNADGGFHL TGRTAYRFAA LVLPHLTGRH RLDEVCAGFG PAQRAMAAEL
610 620 630 640 650
VRTLYARDFA RDIPEADALR PAPEDAAGQR FAAQIAYIDH YTDAAPDRFA
660 670 680 690 700
RYRAARVAVL GTDETARWVA LGLVRNGCGT VGLAADFPDV TGEAAQLAEE
710 720 730 740 750
GCPVSLNRLP DPAEGPGWAA LDGYEVVVVT GPGAAGLTHR LLTEGVPEGR
760 770 780 790 800
TLLPAWAFGE RLVMGPLTTG ADAASATGGC WSCALLRLGA NVDAGTAAAL
810 820 830 840 850
WSEVAGGARS LDAGAPGPLT GPVAAMAGNL LAYEVFRLTS GVQPAETRGQ
860 870 880 890 900
VLIQDLSSLD VLAEPVPPHP RCRHCAPSGV PVTSPGTPEV PRTPSVAGAE
910 920 930 940 950
EAQEVVDALN ATASALVRPH TGVFTRFDDD DLTQTPLKVS RVELALPDGT
960 970 980 990 1000
VRAVTAADIH HLAGARTRAL HRAAVLYVDH TVPAPTAGEE HGAPVAPASL
1010 1020 1030 1040 1050
ATFGGADATP ATAWTPALSL RTGEPHRVPV PAARPFGPHN RLRTHLAATA
1060 1070 1080
GAGAGGSAAE AAGAALLAAL AHTAVLDAVR GR
Length:1,082
Mass (Da):112,768
Last modified:July 13, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF6E1B097EF978CB9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1082Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DS999645 Genomic DNA Translation: EFE83453.2

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
EFE83453; EFE83453; SSHG_03895

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS999645 Genomic DNA Translation: EFE83453.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi457425.XNR_2036

Genome annotation databases

EnsemblBacteriaiEFE83453; EFE83453; SSHG_03895

Phylogenomic databases

eggNOGiENOG4106NCY Bacteria
COG3629 LUCA

Family and domain databases

Gene3Di1.10.10.10, 1 hit
1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR041664 AAA_16
IPR022291 Bacteriocin_synth_cyclodeHase
IPR005158 BTAD
IPR001867 OmpR/PhoB-type_DNA-bd
IPR027417 P-loop_NTPase
IPR016032 Sig_transdc_resp-reg_C-effctor
IPR011990 TPR-like_helical_dom_sf
IPR036388 WH-like_DNA-bd_sf
IPR003776 YcaO-like_dom
PfamiView protein in Pfam
PF13191 AAA_16, 1 hit
PF03704 BTAD, 1 hit
PF00486 Trans_reg_C, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM01043 BTAD, 1 hit
SM00862 Trans_reg_C, 1 hit
SUPFAMiSSF46894 SSF46894, 1 hit
SSF48452 SSF48452, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03882 cyclo_dehyd_2, 1 hit
PROSITEiView protein in PROSITE
PS51755 OMPR_PHOB, 1 hit
PS51664 YCAO, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD6B2R9_9ACTN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D6B2R9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: December 11, 2019
This is version 54 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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