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UniProtKB - D5BCE4 (GGGPS_ZUNPS)
Protein
Geranylgeranylglyceryl phosphate synthase
Gene
ZPR_4469
Organism
Zunongwangia profunda (strain DSM 18752 / CCTCC AB 206139 / SM-A87) (Wangia profunda)
Status
Functioni
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).
UniRule annotation1 PublicationCatalytic activityi
- (2E,6E,10E)-geranylgeranyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphateUniRule annotation1 PublicationEC:2.5.1.41UniRule annotation1 Publication
Cofactori
Mg2+UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 24 | MagnesiumUniRule annotation | 1 | |
Metal bindingi | 52 | MagnesiumUniRule annotation | 1 |
GO - Molecular functioni
- magnesium ion binding Source: UniProtKB-UniRule
- phosphoglycerol geranylgeranyltransferase activity Source: UniProtKB-UniRule
GO - Biological processi
- glycerophospholipid biosynthetic process Source: UniProtKB-UniRule
Keywordsi
Molecular function | Transferase |
Biological process | Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism |
Ligand | Magnesium, Metal-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Geranylgeranylglyceryl phosphate synthaseUniRule annotation (EC:2.5.1.41UniRule annotation1 Publication)Short name: GGGP synthaseUniRule annotation Short name: GGGPSUniRule annotation Alternative name(s): (S)-3-O-geranylgeranylglyceryl phosphate synthaseUniRule annotation Phosphoglycerol geranylgeranyltransferaseUniRule annotation |
Gene namesi | Ordered Locus Names:ZPR_4469Imported |
Organismi | Zunongwangia profunda (strain DSM 18752 / CCTCC AB 206139 / SM-A87) (Wangia profunda) |
Taxonomic identifieri | 655815 [NCBI] |
Taxonomic lineagei | Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Zunongwangia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000436910 | 1 – 234 | Geranylgeranylglyceryl phosphate synthaseAdd BLAST | 234 |
Interactioni
Subunit structurei
Homodimer.
1 PublicationProtein-protein interaction databases
STRINGi | 655815.ZPR_4469 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 172 – 178 | Glycerol-1-phosphate bindingUniRule annotation | 7 | |
Regioni | 203 – 204 | Glycerol-1-phosphate bindingUniRule annotation | 2 | |
Regioni | 225 – 226 | Glycerol-1-phosphate bindingUniRule annotation | 2 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | COG1646, Bacteria |
HOGENOMi | CLU_068610_0_0_10 |
OMAi | ADAIFFM |
OrthoDBi | 1560657at2 |
Family and domain databases
Gene3Di | 3.20.20.390, 1 hit |
HAMAPi | MF_00112, GGGP_HepGP_synthase, 1 hit |
InterProi | View protein in InterPro IPR038597, GGGP/HepGP_synthase_sf IPR008205, GGGP_HepGP_synthase IPR010946, GGGP_synth |
Pfami | View protein in Pfam PF01884, PcrB, 1 hit |
TIGRFAMsi | TIGR01769, GGGP, 1 hit TIGR01768, GGGP-family, 1 hit |
i Sequence
Sequence statusi: Complete.
D5BCE4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPKILDAIIK ASKINKKLLA VLIDPEKFAT ENYSYFIEKL PEAVTHIFVG
60 70 80 90 100
GSTATTAQSE VCVDFIKTKT NLPVILFPGD KEQITEKADG ILLLSLISGR
110 120 130 140 150
NPEYLIEQHI KAVPKLLNAG LEIIPTGYLL LDGGNQSAVA RVSKTKPIQQ
160 170 180 190 200
DEIELIRNTA LAGAMLGKQL VYLEAGSGAL IPVSEKVIAE VKRDLNIPLI
210 220 230
VGGGIRNATQ LKKAYKAGAD LVVIGTAFEN GEFK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP001650 Genomic DNA Translation: ADF54770.1 |
RefSeqi | WP_013073830.1, NC_014041.1 |
Genome annotation databases
EnsemblBacteriai | ADF54770; ADF54770; ZPR_4469 |
KEGGi | zpr:ZPR_4469 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP001650 Genomic DNA Translation: ADF54770.1 |
RefSeqi | WP_013073830.1, NC_014041.1 |
3D structure databases
AlphaFoldDBi | D5BCE4 |
SMRi | D5BCE4 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 655815.ZPR_4469 |
Genome annotation databases
EnsemblBacteriai | ADF54770; ADF54770; ZPR_4469 |
KEGGi | zpr:ZPR_4469 |
Phylogenomic databases
eggNOGi | COG1646, Bacteria |
HOGENOMi | CLU_068610_0_0_10 |
OMAi | ADAIFFM |
OrthoDBi | 1560657at2 |
Family and domain databases
Gene3Di | 3.20.20.390, 1 hit |
HAMAPi | MF_00112, GGGP_HepGP_synthase, 1 hit |
InterProi | View protein in InterPro IPR038597, GGGP/HepGP_synthase_sf IPR008205, GGGP_HepGP_synthase IPR010946, GGGP_synth |
Pfami | View protein in Pfam PF01884, PcrB, 1 hit |
TIGRFAMsi | TIGR01769, GGGP, 1 hit TIGR01768, GGGP-family, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | GGGPS_ZUNPS | |
Accessioni | D5BCE4Primary (citable) accession number: D5BCE4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 6, 2016 |
Last sequence update: | June 15, 2010 | |
Last modified: | May 25, 2022 | |
This is version 57 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |