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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Rickettsia prowazekii (strain Rp22)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationImported

Enzyme and pathway databases

BioCyciRPRO449216:G1GVB-619-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotationImported
Ordered Locus Names:rpr22_CDS582Imported
OrganismiRickettsia prowazekii (strain Rp22)Imported
Taxonomic identifieri449216 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
Proteomesi
  • UP000006931 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

KOiK01056
OMAiRYAHTRH
OrthoDBiPOG091H02CU

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit

Sequencei

Sequence statusi: Complete.

D5AXK5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MILVIGLGNP GTEYQYTRHN IGFIAIERIA SKYHLSFSIK KKFNCEIVEA
60 70 80 90 100
VIDRQKIIFI KPTTYMNLSG KSVILVKTYY NIKYEKVFVI HDDIDLEIGR
110 120 130 140 150
IKFKTGGGNG GHNGLKSIDV VIGNHYNRIR IGIGRPKNNH DVADYVLNNF
160 170 180
SESEYKIAMQ SIDNIANNFG LILEHKLAEF TNKIV
Length:185
Mass (Da):21,035
Last modified:June 15, 2010 - v1
Checksum:i46D960802D912C7F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001584 Genomic DNA Translation: ADE30144.1
RefSeqiWP_014607248.1, NC_017560.1

Genome annotation databases

EnsemblBacteriaiADE30144; ADE30144; rpr22_CDS582
KEGGirpq:rpr22_CDS582
PATRICifig|449216.3.peg.614

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001584 Genomic DNA Translation: ADE30144.1
RefSeqiWP_014607248.1, NC_017560.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADE30144; ADE30144; rpr22_CDS582
KEGGirpq:rpr22_CDS582
PATRICifig|449216.3.peg.614

Phylogenomic databases

KOiK01056
OMAiRYAHTRH
OrthoDBiPOG091H02CU

Enzyme and pathway databases

BioCyciRPRO449216:G1GVB-619-MONOMER

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD5AXK5_RICPP
AccessioniPrimary (citable) accession number: D5AXK5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: March 28, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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