UniProtKB - D5AEK4 (D5AEK4_DROME)
Protein
Submitted name:
MIP20649p
Gene
Mp
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- carbohydrate binding Source: FlyBase
GO - Biological processi
- basement membrane organization Source: FlyBase
- cardiac muscle atrophy Source: FlyBase
- mitochondrion organization Source: FlyBase
- motor neuron axon guidance Source: FlyBase
- positive regulation of integrin-mediated signaling pathway Source: FlyBase
- skeletal muscle atrophy Source: FlyBase
Names & Taxonomyi
Protein namesi | Submitted name: MIP20649pImportedSubmitted name: Multiplexin, isoform PImported |
Gene namesi | Name:MpImported Synonyms:CG14822Imported, CG33171Imported, CG8645Imported, CG8647Imported, COL18A1Imported, CT14872Imported, Dmel\CG42543Imported, DmpImported, dmpImported, mpImported ORF Names:CG42543Imported, Dmel_CG42543Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0260660, Mp |
Subcellular locationi
Other locations
- collagen trimer Source: FlyBase
Expressioni
Gene expression databases
Bgeei | FBgn0260660, Expressed in adult organism and 34 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 19 – 187 | EndostatinInterPro annotationAdd BLAST | 169 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 195 – 215 | DisorderedSequence analysisAdd BLAST | 21 |
Phylogenomic databases
GeneTreei | ENSGT00940000172954 |
HOGENOMi | CLU_004003_1_0_1 |
Family and domain databases
CDDi | cd00247, Endostatin-like, 1 hit |
Gene3Di | 3.10.100.10, 1 hit |
InterProi | View protein in InterPro IPR016186, C-type_lectin-like/link_sf IPR010515, Collagenase_NC10/endostatin IPR016187, CTDL_fold |
Pfami | View protein in Pfam PF06482, Endostatin, 1 hit |
SUPFAMi | SSF56436, SSF56436, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 15 potential isoforms that are computationally mapped.Show allAlign All
D5AEK4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRFDLQSKNL LNSPPPLLNT PTLRVAALNE PSTGDLQGIR GADFACYRQG
60 70 80 90 100
RRAGLLGTFK AFLSSRVQNL DTIVRPADRD LPVVNTRGDV LFNSWKGIFN
110 120 130 140 150
GQGGFFSQAP RIYSFSGKNV MTDSTWPMKM VWHGSLPNGE RSMDTYCDAW
160 170 180 190 200
HSGDHLKGSF ASNLDGHKLL EQKRQSCDSK LIILCVEALS QDRKRKKREI
210 220
GDGSSHGESE SREFKTADEY AAHLENLLL
Computationally mapped potential isoform sequencesi
There are 15 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketE1JID9 | E1JID9_DROME | Multiplexin, isoform G | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 1,023 | Annotation score: | ||
E1JIE0 | E1JIE0_DROME | Multiplexin, isoform M | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 1,017 | Annotation score: | ||
E1JIE1 | E1JIE1_DROME | Multiplexin, isoform B | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 1,008 | Annotation score: | ||
E1JIE2 | E1JIE2_DROME | Multiplexin, isoform L | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 971 | Annotation score: | ||
E1JIE3 | E1JIE3_DROME | Multiplexin, isoform O | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 1,013 | Annotation score: | ||
X2JC42 | X2JC42_DROME | Multiplexin, isoform T | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 1,022 | Annotation score: | ||
X2JCL0 | X2JCL0_DROME | Multiplexin, isoform U | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 973 | Annotation score: | ||
Q86BH1 | Q86BH1_DROME | Multiplexin, isoform E | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 778 | Annotation score: | ||
E1JI49 | E1JI49_DROME | Multiplexin, isoform H | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 813 | Annotation score: | ||
E1JI52 | E1JI52_DROME | Multiplexin, isoform J | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 579 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BT124741 mRNA Translation: ADF27169.1 AE014296 Genomic DNA Translation: AFH04323.1 |
RefSeqi | NP_001246652.1, NM_001259723.1 |
Genome annotation databases
EnsemblMetazoai | FBtr0308094; FBpp0300437; FBgn0260660 |
GeneIDi | 38769 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BT124741 mRNA Translation: ADF27169.1 AE014296 Genomic DNA Translation: AFH04323.1 |
RefSeqi | NP_001246652.1, NM_001259723.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
EnsemblMetazoai | FBtr0308094; FBpp0300437; FBgn0260660 |
GeneIDi | 38769 |
Organism-specific databases
CTDi | 104327 |
FlyBasei | FBgn0260660, Mp |
Phylogenomic databases
GeneTreei | ENSGT00940000172954 |
HOGENOMi | CLU_004003_1_0_1 |
Miscellaneous databases
BioGRID-ORCSi | 38769, 0 hits in 3 CRISPR screens |
GenomeRNAii | 38769 |
Gene expression databases
Bgeei | FBgn0260660, Expressed in adult organism and 34 other tissues |
Family and domain databases
CDDi | cd00247, Endostatin-like, 1 hit |
Gene3Di | 3.10.100.10, 1 hit |
InterProi | View protein in InterPro IPR016186, C-type_lectin-like/link_sf IPR010515, Collagenase_NC10/endostatin IPR016187, CTDL_fold |
Pfami | View protein in Pfam PF06482, Endostatin, 1 hit |
SUPFAMi | SSF56436, SSF56436, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D5AEK4_DROME | |
Accessioni | D5AEK4Primary (citable) accession number: D5AEK4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 15, 2010 |
Last sequence update: | June 15, 2010 | |
Last modified: | February 10, 2021 | |
This is version 82 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |