UniProtKB - D4Q8H0 (D4Q8H0_HUMAN)
Protein
Submitted name:
Protein kinase
Gene
pk
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: InterPro
- protein kinase activity Source: InterPro
Keywordsi
Molecular function | KinaseImported, Transferase |
Names & Taxonomyi
Protein namesi | Submitted name: Protein kinaseImported |
Gene namesi | Name:pkImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000091436.16 |
Subcellular locationi
Cytosol
- cytosol Source: HPA
Expressioni
Gene expression databases
Bgeei | ENSG00000091436, Expressed in heart left ventricle and 234 other tissues |
ExpressionAtlasi | D4Q8H0, baseline and differential |
Genevisiblei | D4Q8H0, HS |
Family & Domainsi
Phylogenomic databases
HOGENOMi | CLU_000288_7_35_1 |
OMAi | KALMMTG |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR001245, Ser-Thr/Tyr_kinase_cat_dom IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF07714, PK_Tyr_Ser-Thr, 1 hit |
PRINTSi | PR00109, TYRKINASE |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
i Sequence
Sequence statusi: Complete.
D4Q8H0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSLGASFVQ IKFDDLQFFE NCGGGSFGSV YRAKWISQDK EVAVKKLLKI
60 70 80 90 100
EKEAEILSVL SHRNIIQFYG VILEPPNYGI VTEYASLGSL YDYINSNRSE
110 120 130 140 150
EMDMDHIMTW ATDVAKGMHY LHMEAPVKVI HRDLKSRNVV IAADGVLKIC
160 170 180 190 200
DFGASRFHNH TTHMSLVGTF PWMAPEVIQS LPVSETCDTY SYGVVLWEML
210 220 230 240 250
TREVPFKGLE GLQVAWLVVE KNERLTIPSS CPRSFAELLH QCWEADAKKR
260 270 280 290 300
PSFKQIISIL ESMSNDTSLP DKCNSFLHNK AEWRCEIEAT LERLKKLERD
310 320 330 340 350
LSFKEQELKE RERRLKMWEQ KLTEQSNTPL LLPLAARMSE ESYFESKTEE
360 370 380 390 400
SNSAEMSCQI TATSNGEGHG MNPSLQAMML MGFGDIFSMN KAGAVMHSGM
410 420 430 440 450
QINMQAKQNS SKTTSKRRGK KVNMALGFSD FDLSEGDDDD DDDGEEEDND
MDNSE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB041883 mRNA Translation: BAJ05400.1 |
RefSeqi | NP_598407.1, NM_133646.2 XP_016859812.1, XM_017004323.1 XP_016859813.1, XM_017004324.1 |
Genome annotation databases
GeneIDi | 51776 |
UCSCi | uc002uhy.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB041883 mRNA Translation: BAJ05400.1 |
RefSeqi | NP_598407.1, NM_133646.2 XP_016859812.1, XM_017004323.1 XP_016859813.1, XM_017004324.1 |
3D structure databases
SMRi | D4Q8H0 |
ModBasei | Search... |
Proteomic databases
EPDi | D4Q8H0 |
PRIDEi | D4Q8H0 |
Protocols and materials databases
Antibodypediai | 2065, 292 antibodies |
DNASUi | 51776 |
Genome annotation databases
GeneIDi | 51776 |
UCSCi | uc002uhy.4, human |
Organism-specific databases
CTDi | 51776 |
VEuPathDBi | HostDB:ENSG00000091436.16 |
Phylogenomic databases
HOGENOMi | CLU_000288_7_35_1 |
OMAi | KALMMTG |
Miscellaneous databases
BioGRID-ORCSi | 51776, 7 hits in 874 CRISPR screens |
ChiTaRSi | MAP3K20, human |
GenomeRNAii | 51776 |
Gene expression databases
Bgeei | ENSG00000091436, Expressed in heart left ventricle and 234 other tissues |
ExpressionAtlasi | D4Q8H0, baseline and differential |
Genevisiblei | D4Q8H0, HS |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR001245, Ser-Thr/Tyr_kinase_cat_dom IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF07714, PK_Tyr_Ser-Thr, 1 hit |
PRINTSi | PR00109, TYRKINASE |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D4Q8H0_HUMAN | |
Accessioni | D4Q8H0Primary (citable) accession number: D4Q8H0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 15, 2010 |
Last sequence update: | June 15, 2010 | |
Last modified: | February 10, 2021 | |
This is version 86 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |