We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - D4GP37 (XACI_HALVD)
Protein
Xylose/arabinose import permease protein XacI
Gene
xacI
Organism
Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
Status
Functioni
Part of the ABC transporter complex XacGHIJK involved in the uptake of xylose and arabinose (PubMed:31089701).
Responsible for the translocation of the substrate across the membrane (Probable).
Curated1 PublicationGO - Biological processi
- carbohydrate transport Source: UniProtKB-KW
- transmembrane transport Source: InterPro
Keywordsi
Biological process | Sugar transport, Transport |
Protein family/group databases
TCDBi | 3.A.1.1.56, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Xylose/arabinose import permease protein XacICurated |
Gene namesi | Name:xacI1 Publication Synonyms:tsgC7Imported Ordered Locus Names:HVO_B0036Imported |
Encoded oni | Plasmid pHV3 |
Organismi | Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) |
Taxonomic identifieri | 309800 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Stenosarchaea group › Halobacteria › Haloferacales › Haloferacaceae › Haloferax › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane Curated; Multi-pass membrane protein Sequence analysis
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 29 – 49 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 89 – 109 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 121 – 141 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 170 – 190 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 227 – 247 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 282 – 302 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000449392 | 1 – 309 | Xylose/arabinose import permease protein XacIAdd BLAST | 309 |
Expressioni
Inductioni
Transcriptionally up-regulated by both L-arabinose and D-xylose via the pentose-specific regulator XacR.1 Publication
Interactioni
Subunit structurei
The complex is composed of two ATP-binding proteins (XacJ and XacK), two transmembrane proteins (XacH and XacI) and a solute-binding protein (XacG).
1 PublicationProtein-protein interaction databases
STRINGi | 309800.C498_01580 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 85 – 297 | ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST | 213 |
Sequence similaritiesi
Belongs to the binding-protein-dependent transport system permease family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | arCOG00159, Archaea |
HOGENOMi | CLU_016047_1_2_2 |
OMAi | FQRNIMS |
OrthoDBi | 46692at2157 |
Family and domain databases
CDDi | cd06261, TM_PBP2, 1 hit |
Gene3Di | 1.10.3720.10, 1 hit |
InterProi | View protein in InterPro IPR000515, MetI-like IPR035906, MetI-like_sf |
Pfami | View protein in Pfam PF00528, BPD_transp_1, 1 hit |
SUPFAMi | SSF161098, SSF161098, 1 hit |
PROSITEi | View protein in PROSITE PS50928, ABC_TM1, 1 hit |
i Sequence
Sequence statusi: Complete.
D4GP37-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSQSSSTGNF DVASLVEDVN LRRVAQYALV VFFLGFFLVP LETGIMTAIK
60 70 80 90 100
TNESVARSLP FAPPVGEGFT LGNIQFALEQ LSGSFFNSLI MSIPATIGSV
110 120 130 140 150
LFGSMAAYGL TMVNWRAQMG MLMLFVVGVF VPYQAVLVPL ARFWNNIFPL
160 170 180 190 200
ARMIEPMVAS IPFFQGYHAE LVPLVITHIA YGIPICTILF RSYYQSLPNS
210 220 230 240 250
LVEAGKIDGA SITKIYRRII LPISKPMFGV VFIYQFTQIY NEFLFAFTLV
260 270 280 290 300
TGSDAPAAPV TLVLPAIGAS TSGINFGIRM SAAFLAAVPT LILYVAFAEQ
FAKGLRTEA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP001953 Genomic DNA Translation: ADE01611.1 |
RefSeqi | WP_004041119.1, NZ_AOHU01000021.1 |
Genome annotation databases
EnsemblBacteriai | ADE01611; ADE01611; HVO_B0036 |
GeneIDi | 8919031 |
KEGGi | hvo:HVO_B0036 |
PATRICi | fig|309800.29.peg.301 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP001953 Genomic DNA Translation: ADE01611.1 |
RefSeqi | WP_004041119.1, NZ_AOHU01000021.1 |
3D structure databases
SMRi | D4GP37 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 309800.C498_01580 |
Protein family/group databases
TCDBi | 3.A.1.1.56, the atp-binding cassette (abc) superfamily |
Genome annotation databases
EnsemblBacteriai | ADE01611; ADE01611; HVO_B0036 |
GeneIDi | 8919031 |
KEGGi | hvo:HVO_B0036 |
PATRICi | fig|309800.29.peg.301 |
Phylogenomic databases
eggNOGi | arCOG00159, Archaea |
HOGENOMi | CLU_016047_1_2_2 |
OMAi | FQRNIMS |
OrthoDBi | 46692at2157 |
Family and domain databases
CDDi | cd06261, TM_PBP2, 1 hit |
Gene3Di | 1.10.3720.10, 1 hit |
InterProi | View protein in InterPro IPR000515, MetI-like IPR035906, MetI-like_sf |
Pfami | View protein in Pfam PF00528, BPD_transp_1, 1 hit |
SUPFAMi | SSF161098, SSF161098, 1 hit |
PROSITEi | View protein in PROSITE PS50928, ABC_TM1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | XACI_HALVD | |
Accessioni | D4GP37Primary (citable) accession number: D4GP37 Secondary accession number(s): L9VI94 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 22, 2020 |
Last sequence update: | May 18, 2010 | |
Last modified: | February 23, 2022 | |
This is version 70 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Plasmid, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families