The new UniProt website is here!
Take me to UniProt BETA
UniProtKB - D4AZD1 (ALG1_ARTBC)
Protein
Chitobiosyldiphosphodolichol beta-mannosyltransferase
Gene
ARB_01551
Organism
Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes)
Status
Functioni
Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc2-Man5 intermediate on the cytoplasmic surface of the ER.
By similarityCatalytic activityi
- GDP-α-D-mannose + N,N'-diacetylchitobiosyl diphosphodolichol = β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-α-D-GlcNAc-diphosphodolichol + GDP + H+By similarityEC:2.4.1.142By similarity
: protein glycosylation Pathwayi
This protein is involved in the pathway protein glycosylation, which is part of Protein modification.By similarityView all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.
GO - Molecular functioni
- chitobiosyldiphosphodolichol beta-mannosyltransferase activity Source: UniProtKB-EC
GO - Biological processi
- protein glycosylation Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Glycosyltransferase, Transferase |
Enzyme and pathway databases
UniPathwayi | UPA00378 |
Names & Taxonomyi
Protein namesi | Recommended name: Chitobiosyldiphosphodolichol beta-mannosyltransferaseBy similarity (EC:2.4.1.142By similarity) |
Gene namesi | ORF Names:ARB_01551 |
Organismi | Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) |
Taxonomic identifieri | 663331 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Onygenales › Arthrodermataceae › Trichophyton › |
Proteomesi |
|
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane Curated; Single-pass type II membrane protein Curated
Endoplasmic reticulum
- endoplasmic reticulum membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 2 | CytoplasmicSequence analysis | 2 | |
Transmembranei | 3 – 23 | Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST | 21 | |
Topological domaini | 24 – 447 | LumenalSequence analysisAdd BLAST | 424 |
Keywords - Cellular componenti
Endoplasmic reticulum, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000434499 | 1 – 447 | Chitobiosyldiphosphodolichol beta-mannosyltransferaseSequence analysisAdd BLAST | 447 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Signal-anchor, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG2941, Eukaryota |
HOGENOMi | CLU_012079_1_0_1 |
OMAi | CWLCARI |
Family and domain databases
InterProi | View protein in InterPro IPR026051, ALG1-like IPR028098, Glyco_trans_4-like_N |
PANTHERi | PTHR13036, PTHR13036, 1 hit |
Pfami | View protein in Pfam PF13579, Glyco_trans_4_4, 1 hit |
i Sequence
Sequence statusi: Complete.
D4AZD1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTLVLLLSIF AICFSSVAFI QLLPTRREKK SSEAHDAVSV QIDTIVCLLR
60 70 80 90 100
PPRSSSNSPT LNRVADSTPN QELLDHPLIS IVALPSPPAL LQTKKKFLFP
110 120 130 140 150
VAAILKVLQQ AWHLWAALGY RTGPAHWILV QNPPAAPTLA LALLACHLRH
160 170 180 190 200
SRLIIDWHNF GYSILALKLG SGHPMVKLME WYEKAFSCYA TAHFCVSNAM
210 220 230 240 250
ARILREQFEI KKPLMVLHDR PSSAFSPIFD EKQRLAILSS IPETSQSAID
260 270 280 290 300
IIEGRCRLLV SSTSWTPDED FSLLLDALCR YSTSAKSSGL PSVPLLVIIT
310 320 330 340 350
GKGPLKDMYL SQIDKLKAEG KLFNVFIKTA WLSFEDYAQL LACATLGVCL
360 370 380 390 400
HTSSSGVDLP MKVVDMFGAG LPVVGWDQYE AWPELVTEGV TGLGFDSADR
410 420 430 440
LSGLLKSVLG GDGSALKVLR EGAVKESRNR WDQTWDPIAG TFLGLVT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | ABSU01000020 Genomic DNA Translation: EFE31651.1 |
RefSeqi | XP_003012291.1, XM_003012245.1 |
Genome annotation databases
EnsemblFungii | EFE31651; EFE31651; ARB_01551 |
GeneIDi | 9519940 |
KEGGi | abe:ARB_01551 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | ABSU01000020 Genomic DNA Translation: EFE31651.1 |
RefSeqi | XP_003012291.1, XM_003012245.1 |
3D structure databases
AlphaFoldDBi | D4AZD1 |
SMRi | D4AZD1 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 663331.D4AZD1 |
Genome annotation databases
EnsemblFungii | EFE31651; EFE31651; ARB_01551 |
GeneIDi | 9519940 |
KEGGi | abe:ARB_01551 |
Phylogenomic databases
eggNOGi | KOG2941, Eukaryota |
HOGENOMi | CLU_012079_1_0_1 |
OMAi | CWLCARI |
Enzyme and pathway databases
UniPathwayi | UPA00378 |
Family and domain databases
InterProi | View protein in InterPro IPR026051, ALG1-like IPR028098, Glyco_trans_4-like_N |
PANTHERi | PTHR13036, PTHR13036, 1 hit |
Pfami | View protein in Pfam PF13579, Glyco_trans_4_4, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ALG1_ARTBC | |
Accessioni | D4AZD1Primary (citable) accession number: D4AZD1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 14, 2015 |
Last sequence update: | May 18, 2010 | |
Last modified: | May 25, 2022 | |
This is version 41 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families