Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Lysophospholipase ARB_05919

Gene

ARB_05919

Organism
Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalyzes the release of fatty acids from lysophospholipids (By similarity). Phospholipase B may well contribute to pathogenicity by abetting the fungus in damaging host cell membranes (By similarity).By similarity

Catalytic activityi

2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processLipid degradation, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Lysophospholipase ARB_05919Curated (EC:3.1.1.5By similarity)
Alternative name(s):
Phospholipase BCurated
Gene namesi
ORF Names:ARB_05919
OrganismiArthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes)
Taxonomic identifieri663331 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesArthrodermataceaeTrichophyton
Proteomesi
  • UP000008866 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500143781823 – 643Lysophospholipase ARB_05919Sequence analysisAdd BLAST621

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi142N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi176N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi195N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi293N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi466N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi472N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi482N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi503N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi524N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi533N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi552N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi597N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi663331.XP_003015608.1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 597PLA2cPROSITE-ProRule annotationAdd BLAST548

Sequence similaritiesi

Belongs to the lysophospholipase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1325 Eukaryota
ENOG410XR72 LUCA
KOiK13333
OrthoDBiEOG092C2IZ9

Family and domain databases

InterProiView protein in InterPro
IPR016035 Acyl_Trfase/lysoPLipase
IPR002642 LysoPLipase_cat_dom
PfamiView protein in Pfam
PF01735 PLA2_B, 1 hit
SMARTiView protein in SMART
SM00022 PLAc, 1 hit
SUPFAMiSSF52151 SSF52151, 1 hit
PROSITEiView protein in PROSITE
PS51210 PLA2C, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

D4ANV2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMFIPATLGT FVLASLLPAT VGAGIPNAAA DVAVRALPNA PDGYAPAEVD
60 70 80 90 100
CPSTKPAVRS AAKLSQQEQD WLKKRRMKTT GAMADFFSRV KIEGFDAVAY
110 120 130 140 150
LVGNADNVAK LPNVAIAVSG GGYRALMNGA GALKAFDSRT DNSTEPGQLG
160 170 180 190 200
GLLQSATYLS GLSGGGWLLG SMYVNNDSTI TELQKGGSNS LWKFNRSILE
210 220 230 240 250
GPDDGSSGVV DTAEYYKEMI KEISRKKAAG FETSITDIWG RALSYQLINA
260 270 280 290 300
PKGGPAYTWS SISQNSKFQS GDVPFPLLVA DGRNPGEKLI GGNATIFEFN
310 320 330 340 350
PYEFGTWDPT IFGFVPTQYI GSKFEAGTLP SDEKCVRGMD NAGFIMGTSS
360 370 380 390 400
SLFNQFALHL DSQDLPKVVK DSLRDFLSSL DEANNDIAEY KPNPFFGYAK
410 420 430 440 450
STSPFAGVKS LPVVDGGEDK QNIPFHPLIQ PARHVDVIFA IDSSADTELA
460 470 480 490 500
WPNGDSIIAT YQRSLNSTGI ANGTSFPAIP DNNTFINLGL NHNPTFFGCD
510 520 530 540 550
SSNTTNPTPL IVYIPNSPYV THSNVSTFNL KYNTTQRDAI ILNGYNVATM
560 570 580 590 600
ANATRDGNWP TCVGCAMLSR SLERTKTAVP DACKQCFKMY CWDGTLNSTK
610 620 630 640
PDVYDPKLFL TEVDLQSAAK GLHASGKLSL VAAVVTLLSI LLV
Length:643
Mass (Da):68,923
Last modified:May 18, 2010 - v1
Checksum:iC5A464D2DD1B5AD8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABSU01000004 Genomic DNA Translation: EFE34963.1
RefSeqiXP_003015608.1, XM_003015562.1

Genome annotation databases

EnsemblFungiiEFE34963; EFE34963; ARB_05919
GeneIDi9525889
KEGGiabe:ARB_05919

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABSU01000004 Genomic DNA Translation: EFE34963.1
RefSeqiXP_003015608.1, XM_003015562.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi663331.XP_003015608.1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEFE34963; EFE34963; ARB_05919
GeneIDi9525889
KEGGiabe:ARB_05919

Phylogenomic databases

eggNOGiKOG1325 Eukaryota
ENOG410XR72 LUCA
KOiK13333
OrthoDBiEOG092C2IZ9

Family and domain databases

InterProiView protein in InterPro
IPR016035 Acyl_Trfase/lysoPLipase
IPR002642 LysoPLipase_cat_dom
PfamiView protein in Pfam
PF01735 PLA2_B, 1 hit
SMARTiView protein in SMART
SM00022 PLAc, 1 hit
SUPFAMiSSF52151 SSF52151, 1 hit
PROSITEiView protein in PROSITE
PS51210 PLA2C, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPLB1_ARTBC
AccessioniPrimary (citable) accession number: D4ANV2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 20, 2016
Last sequence update: May 18, 2010
Last modified: May 10, 2017
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again