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UniProtKB - D4AD65 (D4AD65_RAT)
Protein
Submitted name:
Folliculogenesis-specific bHLH transcription factor
Gene
Figla
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- bHLH transcription factor binding Source: RGD
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: RGD
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- protein dimerization activity Source: InterPro
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: RGD
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific double-stranded DNA binding Source: RGD
GO - Biological processi
- developmental process Source: GO_Central
- positive regulation of transcription by RNA polymerase II Source: RGD
- regulation of transcription by RNA polymerase II Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: Folliculogenesis-specific bHLH transcription factor |
Gene namesi | Name:FiglaImported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1564754, Figla |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000015877, Expressed in female gonad and 3 other tissues |
Interactioni
GO - Molecular functioni
- bHLH transcription factor binding Source: RGD
- protein dimerization activity Source: InterPro
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000021272 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 60 – 112 | BHLHInterPro annotationAdd BLAST | 53 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 122 – 162 | DisorderedSequence analysisAdd BLAST | 41 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 131 – 158 | Polar residuesSequence analysisAdd BLAST | 28 |
Phylogenomic databases
eggNOGi | KOG4029, Eukaryota |
GeneTreei | ENSGT00440000033552 |
HOGENOMi | CLU_1380972_0_0_1 |
InParanoidi | D4AD65 |
OMAi | ELAHTCR |
OrthoDBi | 1245774at2759 |
PhylomeDBi | D4AD65 |
TreeFami | TF351992 |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
i Sequence
Sequence statusi: Complete.
D4AD65-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDTSSPASPE PFLATPQAEV LEELLQTQLG PLPRLAAICR LKRLPSGGYS
60 70 80 90 100
TTDDLHLVLE RRRVANAKER ERIKNLNRGF AKLKALVPFL PQSRKPSKVD
110 120 130 140 150
ILKGATEYIR ILGCVLEGAK ASEKQGPEEQ QVHSSRPSDP HVSSTRELLG
160 170 180 190
NATQPTGCAS GLKKEEEGPW AYGGHSELYS YHQSAVPETR SYFIH
Sequence databases
RefSeqi | XP_575589.1, XM_575589.6 |
Genome annotation databases
Ensembli | ENSRNOT00000021272.3; ENSRNOP00000021272.1; ENSRNOG00000015877.3 |
GeneIDi | 500239 |
KEGGi | rno:500239 |
UCSCi | RGD:1564754, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_575589.1, XM_575589.6 |
3D structure databases
AlphaFoldDBi | D4AD65 |
SMRi | D4AD65 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000021272 |
Proteomic databases
PaxDbi | D4AD65 |
Genome annotation databases
Ensembli | ENSRNOT00000021272.3; ENSRNOP00000021272.1; ENSRNOG00000015877.3 |
GeneIDi | 500239 |
KEGGi | rno:500239 |
UCSCi | RGD:1564754, rat |
Organism-specific databases
CTDi | 344018 |
RGDi | 1564754, Figla |
Phylogenomic databases
eggNOGi | KOG4029, Eukaryota |
GeneTreei | ENSGT00440000033552 |
HOGENOMi | CLU_1380972_0_0_1 |
InParanoidi | D4AD65 |
OMAi | ELAHTCR |
OrthoDBi | 1245774at2759 |
PhylomeDBi | D4AD65 |
TreeFami | TF351992 |
Gene expression databases
Bgeei | ENSRNOG00000015877, Expressed in female gonad and 3 other tissues |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | D4AD65_RAT | |
Accessioni | D4AD65Primary (citable) accession number: D4AD65 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | April 20, 2010 | |
Last modified: | May 25, 2022 | |
This is version 81 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |