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UniProtKB - D4A919 (D4A919_RAT)
Protein
Submitted name:
Scratch family transcriptional repressor 1
Gene
Scrt1
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- DNA-binding transcription repressor activity, RNA polymerase II-specific Source: RGD
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: RGD
- sequence-specific DNA binding Source: RGD
- sequence-specific double-stranded DNA binding Source: RGD
GO - Biological processi
- negative regulation of transcription by RNA polymerase II Source: RGD
- regulation of neuron migration Source: RGD
- regulation of transcription, DNA-templated Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Scratch family transcriptional repressor 1Submitted name: Scratch homolog 1, zinc finger protein (Drosophila) (Predicted)Imported |
Gene namesi | ORF Names:rCG_59387Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1306236, Scrt1 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000025594, Expressed in frontal cortex and 13 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 191 – 218 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 248 – 275 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 276 – 303 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 304 – 322 | C2H2-typeInterPro annotationAdd BLAST | 19 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 130 – 190 | DisorderedSequence analysisAdd BLAST | 61 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG2462, Eukaryota |
GeneTreei | ENSGT00940000154491 |
HOGENOMi | CLU_002678_42_3_1 |
OMAi | RCHKAFA |
OrthoDBi | 1332418at2759 |
TreeFami | TF315515 |
Family and domain databases
InterProi | View protein in InterPro IPR029794, SCRATCH1/2 IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
PANTHERi | PTHR24388:SF60, PTHR24388:SF60, 1 hit |
Pfami | View protein in Pfam PF00096, zf-C2H2, 4 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 5 hits |
SUPFAMi | SSF57667, SSF57667, 3 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 4 hits |
i Sequence
Sequence statusi: Complete.
D4A919-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPRSFLVKKV KLDTFSSADL DSSYGRARSD LGVRLQDKGY LSDYVGPASV
60 70 80 90 100
YDGDAEAALL KGPSPEPMYA AAVRGELGPA ASGSAPPPTP RPELATAAGG
110 120 130 140 150
YINGDAAVSE GYAADAFFIT DGRSRRKAAN ANAASAPSTA SVAAPDSDAG
160 170 180 190 200
GGGGPGTRGS GSGSASRGGT RVGAGTEARA GPGATGAGGR HACGECGKTY
210 220 230 240 250
ATSSNLSRHK QTHRSLDSQL ARRCPTCGKV YVSMPAMAMH LLTHDLRHKC
260 270 280 290 300
GVCGKAFSRP WLLQGHMRSH TGEKPFGCAH CGKAFADRSN LRAHMQTHSA
310 320 330 340
FKHFQCKRCK KSFALKSYLN KHYESACFKG GASGPATPAP PQLSPVQA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH473950 Genomic DNA Translation: EDM15967.1 |
RefSeqi | NP_001124042.1, NM_001130570.1 |
Genome annotation databases
Ensembli | ENSRNOT00000035423.4; ENSRNOP00000030637.3; ENSRNOG00000025594.4 |
GeneIDi | 366951 |
KEGGi | rno:366951 |
UCSCi | RGD:1306236, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH473950 Genomic DNA Translation: EDM15967.1 |
RefSeqi | NP_001124042.1, NM_001130570.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000030637 |
Genome annotation databases
Ensembli | ENSRNOT00000035423.4; ENSRNOP00000030637.3; ENSRNOG00000025594.4 |
GeneIDi | 366951 |
KEGGi | rno:366951 |
UCSCi | RGD:1306236, rat |
Organism-specific databases
CTDi | 83482 |
RGDi | 1306236, Scrt1 |
Phylogenomic databases
eggNOGi | KOG2462, Eukaryota |
GeneTreei | ENSGT00940000154491 |
HOGENOMi | CLU_002678_42_3_1 |
OMAi | RCHKAFA |
OrthoDBi | 1332418at2759 |
TreeFami | TF315515 |
Miscellaneous databases
PROi | PR:D4A919 |
Gene expression databases
Bgeei | ENSRNOG00000025594, Expressed in frontal cortex and 13 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR029794, SCRATCH1/2 IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
PANTHERi | PTHR24388:SF60, PTHR24388:SF60, 1 hit |
Pfami | View protein in Pfam PF00096, zf-C2H2, 4 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 5 hits |
SUPFAMi | SSF57667, SSF57667, 3 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 4 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | D4A919_RAT | |
Accessioni | D4A919Primary (citable) accession number: D4A919 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | April 20, 2010 | |
Last modified: | May 25, 2022 | |
This is version 82 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |