Scrt1

Functionⁱ

GO - Molecular functionⁱ

DNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
DNA-binding transcription factor activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
DNA-binding transcription repressor activity, RNA polymerase II-specific Source: Ensembl
RNA polymerase II regulatory region sequence-specific DNA binding Source: Ensembl

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

regulation of neuron migration Source: Ensembl
regulation of transcription, DNA-templated
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Scratch family transcriptional repressor 1Imported Submitted name: Scratch homolog 1, zinc finger protein (Drosophila) (Predicted)Imported
Gene namesⁱ	Name:Scrt1Imported Synonyms:Scrt1_predictedImported ORF Names:rCG_59387Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 7

Organism-specific databases

Rat genome database More...RGDⁱ	1306236 Scrt1

RGDⁱ

1306236 Scrt1

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

PRIDEⁱ	D4A919

PRIDEⁱ

D4A919

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000025594 Expressed in 3 organ(s), highest expression level in brain

Bgeeⁱ

ENSRNOG00000025594 Expressed in 3 organ(s), highest expression level in brain

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000030637

STRINGⁱ

10116.ENSRNOP00000030637

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	191 – 218	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	248 – 275	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	276 – 303	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	304 – 322	C2H2-typeInterPro annotationAdd BLAST	19

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG2462 Eukaryota ENOG41106JS LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000011027
KEGG Orthology (KO) More...KOⁱ	K09219
OMAⁱ	AFFIMDG
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0Q0V
TreeFamⁱ	TF315515

Family and domain databases

InterProⁱ	View protein in InterPro IPR029794 SCRATCH1/2 IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
PANTHERⁱ	PTHR44270 PTHR44270, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 4 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF57667 SSF57667, 3 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

D4A919-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPRSFLVKKV KLDTFSSADL DSSYGRARSD LGVRLQDKGY LSDYVGPASV 
        60         70         80         90        100
YDGDAEAALL KGPSPEPMYA AAVRGELGPA ASGSAPPPTP RPELATAAGG 
       110        120        130        140        150
YINGDAAVSE GYAADAFFIT DGRSRRKAAN ANAASAPSTA SVAAPDSDAG 
       160        170        180        190        200
GGGGPGTRGS GSGSASRGGT RVGAGTEARA GPGATGAGGR HACGECGKTY 
       210        220        230        240        250
ATSSNLSRHK QTHRSLDSQL ARRCPTCGKV YVSMPAMAMH LLTHDLRHKC 
       260        270        280        290        300
GVCGKAFSRP WLLQGHMRSH TGEKPFGCAH CGKAFADRSN LRAHMQTHSA 
       310        320        330        340 
FKHFQCKRCK KSFALKSYLN KHYESACFKG GASGPATPAP PQLSPVQA

Length:348

Mass (Da):35,945

Last modified:April 20, 2010 - v1

Checksum:ⁱB44A339197B3E2A0

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC139605 Genomic DNA No translation available. CH473950 Genomic DNA Translation: EDM15967.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001124042.1, NM_001130570.1
UniGeneⁱ	Rn.220523

Genome annotation databases

Ensemblⁱ	ENSRNOT00000035423; ENSRNOP00000030637; ENSRNOG00000025594
GeneIDⁱ	366951
KEGGⁱ	rno:366951
UCSC genome browser More...UCSCⁱ	RGD:1306236 rat

Protein	Similar proteins		Species	Score	Length	Source
D4A919	Transcriptional repressor scratch 1		HUMAN		348	UniRef90_Q9BWW7
Transcriptional repressor scratch 1		MOUSE		348
Uncharacterized protein		CERAT		348
Uncharacterized protein		PAPAN		348
Uncharacterized protein		CHLSB		348
+54

Protein	Similar proteins		Species	Score	Length	Source
D4A919	Transcriptional repressor scratch 1		HUMAN		348	UniRef50_Q9BWW7
Transcriptional repressor scratch 1		MOUSE		348
Uncharacterized protein		CERAT		348
Uncharacterized protein		PAPAN		348
Uncharacterized protein		CHLSB		348
+224

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC139605 Genomic DNA No translation available. CH473950 Genomic DNA Translation: EDM15967.1
RefSeqⁱ	NP_001124042.1, NM_001130570.1
UniGeneⁱ	Rn.220523

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000030637

STRINGⁱ

10116.ENSRNOP00000030637

Proteomic databases

PRIDEⁱ	D4A919

PRIDEⁱ

D4A919

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000035423; ENSRNOP00000030637; ENSRNOG00000025594
GeneIDⁱ	366951
KEGGⁱ	rno:366951
UCSCⁱ	RGD:1306236 rat

Organism-specific databases

CTDⁱ	83482
RGDⁱ	1306236 Scrt1

Phylogenomic databases

eggNOGⁱ	KOG2462 Eukaryota ENOG41106JS LUCA
GeneTreeⁱ	ENSGT00390000011027
KOⁱ	K09219
OMAⁱ	AFFIMDG
OrthoDBⁱ	EOG091G0Q0V
TreeFamⁱ	TF315515

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:D4A919

PROⁱ

PR:D4A919

Gene expression databases

Bgeeⁱ	ENSRNOG00000025594 Expressed in 3 organ(s), highest expression level in brain

Bgeeⁱ

ENSRNOG00000025594 Expressed in 3 organ(s), highest expression level in brain

Family and domain databases

InterProⁱ	View protein in InterPro IPR029794 SCRATCH1/2 IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
PANTHERⁱ	PTHR44270 PTHR44270, 1 hit
Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 4 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF57667 SSF57667, 3 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	D4A919_RAT
Accessionⁱ	D4A919Primary (citable) accession number: D4A919
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 20, 2010
	Last sequence update:	April 20, 2010
	Last modified:	November 7, 2018
	This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - D4A919 (D4A919_RAT)

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Scratch family transcriptional repressor 1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ