Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 85 (03 Jul 2019)
Sequence version 1 (20 Apr 2010)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

Olfactory receptor 1273

Gene

LOC100909937

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionG-protein coupled receptorSAAS annotation, Receptor, Transducer
Biological processOlfactionSAAS annotation, Sensory transduction

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Olfactory receptor 1273Imported
Submitted name:
Olfactory receptor 1273 (Predicted)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LOC100909937Imported
Synonyms:LOC100909958Imported, LOC100910086Imported, LOC100910153Imported, LOC100910227Imported, LOC100910363Imported, LOC100910548Imported, Olr1273Imported, Olr1273_predictedImported
ORF Names:rCG_40995Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 2, Chromosome 8

Organism-specific databases

Rat genome database

More...
RGDi
6500980 LOC100909937
6501087 LOC100909958
6499955 LOC100910086
6499688 LOC100910153
6499495 LOC100910227
6498905 LOC100910363
6497945 LOC100910548
1333145 Olr1273

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei30 – 48HelicalSequence analysisAdd BLAST19
Transmembranei55 – 74HelicalSequence analysisAdd BLAST20
Transmembranei89 – 118HelicalSequence analysisAdd BLAST30
Transmembranei138 – 162HelicalSequence analysisAdd BLAST25
Transmembranei203 – 224HelicalSequence analysisAdd BLAST22
Transmembranei236 – 259HelicalSequence analysisAdd BLAST24
Transmembranei265 – 288HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000067229

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini39 – 286G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST248

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182884

KEGG Orthology (KO)

More...
KOi
K04257

Identification of Orthologs from Complete Genome Data

More...
OMAi
FICISRA

Database of Orthologous Groups

More...
OrthoDBi
885965at2759

TreeFam database of animal gene trees

More...
TreeFami
TF336512

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13853 7tm_4, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00237 GPCRRHODOPSN
PR00245 OLFACTORYR

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D4A8K9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSNLSIVTQF ILLGIPHTEG VETMLFVLFL SFYIFTLVGN VLILLTIVSS
60 70 80 90 100
NRLHTPMYFF LCQLSVCDIF FPSVSSPKML FYLSGNSRAI SYAGCVCQLF
110 120 130 140 150
FYHFLGCTEC FLYTVMAYDR FIAICFPLRY SIIMNHRVCA ILAVGTLFFG
160 170 180 190 200
CIQATFLTAL TFQLPYCGPN EVEYYFCDIP VMLKLACADT SALEMVGLIS
210 220 230 240 250
VGLMPLSCFL LILTSYSFIL CSILQIRSTE GRHRAFSTCS AHLAAILLAF
260 270 280 290 300
MPVVLIYLQP TPNPWLNAAV QVLNNLVTPM LNPLIYSLRN KEVKCSLKKV
310
LQQALILSKR R
Length:311
Mass (Da):34,986
Last modified:April 20, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i99B5EDE68E3805A3
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AABR07007924 Genomic DNA No translation available.
AABR07007928 Genomic DNA No translation available.
AABR07009890 Genomic DNA No translation available.
AABR07009891 Genomic DNA No translation available.
AABR07009892 Genomic DNA No translation available.
AABR07069944 Genomic DNA No translation available.
AABR07069957 Genomic DNA No translation available.
CH474180 Genomic DNA Translation: EDL84280.1

NCBI Reference Sequences

More...
RefSeqi
NP_001000458.1, NM_001000458.1
XP_003749228.1, XM_003749180.1
XP_003749234.1, XM_003749186.1
XP_003749307.1, XM_003749259.1
XP_003749310.1, XM_003749262.1
XP_003749313.1, XM_003749265.1
XP_003750538.1, XM_003750490.1
XP_003750545.1, XM_003750497.1
XP_017443875.1, XM_017588386.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000071050; ENSRNOP00000064893; ENSRNOG00000048702
ENSRNOT00000071905; ENSRNOP00000066208; ENSRNOG00000049978
ENSRNOT00000073329; ENSRNOP00000064042; ENSRNOG00000046225
ENSRNOT00000073494; ENSRNOP00000064950; ENSRNOG00000047788
ENSRNOT00000074802; ENSRNOP00000067229; ENSRNOG00000047523
ENSRNOT00000086631; ENSRNOP00000069813; ENSRNOG00000058097
ENSRNOT00000090325; ENSRNOP00000068766; ENSRNOG00000057610

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100909937
100909958
100910086
100910153
100910227
100910363
100910548
300589

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:100909937
rno:100909958
rno:100910086
rno:100910153
rno:100910227
rno:100910363
rno:100910548
rno:300589

UCSC genome browser

More...
UCSCi
RGD:1333145 rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07007924 Genomic DNA No translation available.
AABR07007928 Genomic DNA No translation available.
AABR07009890 Genomic DNA No translation available.
AABR07009891 Genomic DNA No translation available.
AABR07009892 Genomic DNA No translation available.
AABR07069944 Genomic DNA No translation available.
AABR07069957 Genomic DNA No translation available.
CH474180 Genomic DNA Translation: EDL84280.1
RefSeqiNP_001000458.1, NM_001000458.1
XP_003749228.1, XM_003749180.1
XP_003749234.1, XM_003749186.1
XP_003749307.1, XM_003749259.1
XP_003749310.1, XM_003749262.1
XP_003749313.1, XM_003749265.1
XP_003750538.1, XM_003750490.1
XP_003750545.1, XM_003750497.1
XP_017443875.1, XM_017588386.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000067229

Protein family/group databases

Information system for G protein-coupled receptors (GPCRs)

More...
GPCRDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000071050; ENSRNOP00000064893; ENSRNOG00000048702
ENSRNOT00000071905; ENSRNOP00000066208; ENSRNOG00000049978
ENSRNOT00000073329; ENSRNOP00000064042; ENSRNOG00000046225
ENSRNOT00000073494; ENSRNOP00000064950; ENSRNOG00000047788
ENSRNOT00000074802; ENSRNOP00000067229; ENSRNOG00000047523
ENSRNOT00000086631; ENSRNOP00000069813; ENSRNOG00000058097
ENSRNOT00000090325; ENSRNOP00000068766; ENSRNOG00000057610
GeneIDi100909937
100909958
100910086
100910153
100910227
100910363
100910548
300589
KEGGirno:100909937
rno:100909958
rno:100910086
rno:100910153
rno:100910227
rno:100910363
rno:100910548
rno:300589
UCSCiRGD:1333145 rat

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
300589
RGDi6500980 LOC100909937
6501087 LOC100909958
6499955 LOC100910086
6499688 LOC100910153
6499495 LOC100910227
6498905 LOC100910363
6497945 LOC100910548
1333145 Olr1273

Phylogenomic databases

GeneTreeiENSGT00950000182884
KOiK04257
OMAiFICISRA
OrthoDBi885965at2759
TreeFamiTF336512

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD4A8K9_RAT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D4A8K9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: July 3, 2019
This is version 85 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again