UniProtKB - D4A617 (D4A617_RAT)
Protein
Submitted name:
Ectonucleoside triphosphate diphosphohydrolase 1
Gene
LOC103689954
Organism
Rattus norvegicus (Rat)
Status
Functioni
Cofactori
Protein has several cofactor binding sites:Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 174 | Proton acceptorUniRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 215 – 219 | ATPUniRule annotation | 5 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- hydrolase activity Source: UniProtKB-KW
Keywordsi
Molecular function | HydrolaseUniRule annotationARBA annotation |
Ligand | ATP-bindingUniRule annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: Ectonucleoside triphosphate diphosphohydrolase 1Imported |
Gene namesi | Name:LOC103689954Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 9454627, LOC103689954 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 17 – 37 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSRNOG00000046546, Expressed in testis and 17 other tissues |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
eggNOGi | KOG1386, Eukaryota |
GeneTreei | ENSGT01010000222402 |
HOGENOMi | CLU_010246_2_3_1 |
InParanoidi | D4A617 |
OMAi | QKSSWFN |
TreeFami | TF332859 |
Family and domain databases
InterProi | View protein in InterPro IPR000407, GDA1_CD39_NTPase |
PANTHERi | PTHR11782, PTHR11782, 1 hit |
Pfami | View protein in Pfam PF01150, GDA1_CD39, 1 hit |
PROSITEi | View protein in PROSITE PS01238, GDA1_CD39_NTPASE, 1 hit |
i Sequence
Sequence statusi: Complete.
D4A617-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
LFLALDSKVK RFCSKNILII LGFSSVLAVI ALIAVGLTQN KPLPENVKYG
60 70 80 90 100
IVLDAGSSHT NLYIYKWPAE KENDTGVVQQ LEECQVKGPG ISKYAQKTDE
110 120 130 140 150
IAAYLAECMK MSTERIPASK QHQTPVYLGA TAGMRLLRME SKQSADEVLA
160 170 180 190 200
AVSRSLKSYP FDFQGAKIIT GQEEGAYGWI TINYLLGRFT QEQSWLNFIS
210 220 230 240 250
DSQKQATFGA LDLGGASTQI TFVPLNSTLE APETSLQFRL YGTDYTVYTH
260 270 280 290 300
SFLCYGKDQA LWQKLAQDIQ VSSGGILKDP CFYPGYKKVV NVSELYGTPC
310 320 330 340 350
TKRFEKKLPF NQFQVQGTGD YEQCHQSILK LFNNSHCPYS QCAFNGVFLP
360 370 380 390 400
PLQGSFGAFS AFYFVMDFFK KMANDSVSSQ EKMTEITKNF CSKPWEEVKA
410 420 430 440 450
SYPTVKEKYL SEYCFSGTYI LSLLLQGYNF TGTSWDQIHF MGKVTWESVG
460
GVEVGDKVVL NLENV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07072054 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSRNOT00000019751; ENSRNOP00000019751; ENSRNOG00000046546 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07072054 Genomic DNA No translation available. |
3D structure databases
SMRi | D4A617 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000019751 |
Proteomic databases
PaxDbi | D4A617 |
PeptideAtlasi | D4A617 |
PRIDEi | D4A617 |
Genome annotation databases
Ensembli | ENSRNOT00000019751; ENSRNOP00000019751; ENSRNOG00000046546 |
Organism-specific databases
RGDi | 9454627, LOC103689954 |
Phylogenomic databases
eggNOGi | KOG1386, Eukaryota |
GeneTreei | ENSGT01010000222402 |
HOGENOMi | CLU_010246_2_3_1 |
InParanoidi | D4A617 |
OMAi | QKSSWFN |
TreeFami | TF332859 |
Gene expression databases
Bgeei | ENSRNOG00000046546, Expressed in testis and 17 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR000407, GDA1_CD39_NTPase |
PANTHERi | PTHR11782, PTHR11782, 1 hit |
Pfami | View protein in Pfam PF01150, GDA1_CD39, 1 hit |
PROSITEi | View protein in PROSITE PS01238, GDA1_CD39_NTPASE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D4A617_RAT | |
Accessioni | D4A617Primary (citable) accession number: D4A617 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | April 3, 2013 | |
Last modified: | December 2, 2020 | |
This is version 62 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |