Ovol2

Functionⁱ

GO - Molecular functionⁱ

chromatin binding Source: Ensembl
DNA-binding transcription activator activity, RNA polymerase II-specific
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
sequence-specific DNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

angiogenesis Source: Ensembl
cellular response to transforming growth factor beta stimulus Source: Ensembl
dorsal/ventral pattern formation Source: Ensembl
embryonic digestive tract morphogenesis Source: Ensembl
endocardium formation Source: Ensembl
epidermal cell differentiation
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
heart looping Source: Ensembl
heart trabecula formation Source: Ensembl
labyrinthine layer blood vessel development Source: Ensembl
negative regulation of epithelial to mesenchymal transition Source: Ensembl
negative regulation of stem cell proliferation Source: Ensembl
negative regulation of transcription, DNA-templated
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
neural crest cell migration Source: Ensembl
neural fold formation Source: Ensembl
positive regulation of keratinocyte differentiation Source: Ensembl
regulation of keratinocyte proliferation Source: Ensembl
regulation of SMAD protein signal transduction Source: Ensembl

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Ovo-like zinc finger 2Imported Submitted name: Zinc finger protein 339 (Predicted), isoform CRA_bImported
Gene namesⁱ	Name:Ovol2Imported Synonyms:Zfp339_predictedImported ORF Names:rCG_27483Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 3

Organism-specific databases

Rat genome database More...RGDⁱ	1306130 Ovol2

RGDⁱ

1306130 Ovol2

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

PRIDEⁱ	D4A5U5

PRIDEⁱ

D4A5U5

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000006850 Expressed in 5 organ(s), highest expression level in colon

Bgeeⁱ

ENSRNOG00000006850 Expressed in 5 organ(s), highest expression level in colon

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000061477

STRINGⁱ

10116.ENSRNOP00000061477

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	85 – 112	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	113 – 140	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	141 – 169	C2H2-typeInterPro annotationAdd BLAST	29
Domainⁱ	180 – 208	C2H2-typeInterPro annotationAdd BLAST	29

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG3576 Eukaryota ENOG4111H28 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00920000149010
KEGG Orthology (KO) More...KOⁱ	K09216
OMAⁱ	FTTGTCN
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0LB1

Family and domain databases

InterProⁱ	View protein in InterPro IPR027756 Ovo-like IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
PANTHERⁱ	PTHR10032 PTHR10032, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 2 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 4 hits
SUPFAMⁱ	SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 2 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

D4A5U5-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSLGCLLRDP PEDCRSDGGS SSGCSCSAGE PGGAESSSSP RAPEPETPEL 
        60         70         80         90        100
HDAEGTDGHL AAMQRPVARS KIKFTTGTCN DSVIHNCDLC GKSFRLQRML 
       110        120        130        140        150
NRHLKCHNQV KRHLCTFCGK GFNDTFDLKR HVRTHTGIRP YKCEVCYKAF 
       160        170        180        190        200
TQRCSLESHL KKIHGVQQQY AYKQRRDKLY VCEDCGYTGP TQEDLYLHVN 
       210        220        230        240 
SAHPGSTFLK KTSKKLAALM QNKLTSPLQE NSTLSEEEEK K

Length:241

Mass (Da):26,897

Last modified:April 20, 2010 - v1

Checksum:ⁱ95857CFD8E0E08D8

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07054062 Genomic DNA No translation available. CH474026 Genomic DNA Translation: EDL95169.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001099989.1, NM_001106519.1
UniGeneⁱ	Rn.104639

Genome annotation databases

Ensemblⁱ	ENSRNOT00000065553; ENSRNOP00000061477; ENSRNOG00000006850
GeneIDⁱ	296201
KEGGⁱ	rno:296201

Protein	Similar proteins		Species	Score	Length	Source
D4A5U5	Transcription factor Ovo-like 2		MOUSE		274	UniRef90_Q8CIV7
transcription factor Ovo-like 2		MESAU		104
UPI00038BB6D1		MICOH		279
UPI000333100A		JACJA		276
UPI000017E5FE		RAT		274
+12

Protein	Similar proteins		Species	Score	Length	Source
D4A5U5	Transcription factor Ovo-like 2		MOUSE		274	UniRef50_Q8CIV7
transcription factor Ovo-like 2		MESAU		104
Uncharacterized protein		RABIT		254
UPI00038BB6D1		MICOH		279
UPI000333100A		JACJA		276
+19

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07054062 Genomic DNA No translation available. CH474026 Genomic DNA Translation: EDL95169.1
RefSeqⁱ	NP_001099989.1, NM_001106519.1
UniGeneⁱ	Rn.104639

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000061477

STRINGⁱ

10116.ENSRNOP00000061477

Proteomic databases

PRIDEⁱ	D4A5U5

PRIDEⁱ

D4A5U5

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000065553; ENSRNOP00000061477; ENSRNOG00000006850
GeneIDⁱ	296201
KEGGⁱ	rno:296201

Organism-specific databases

CTDⁱ	58495
RGDⁱ	1306130 Ovol2

Phylogenomic databases

eggNOGⁱ	KOG3576 Eukaryota ENOG4111H28 LUCA
GeneTreeⁱ	ENSGT00920000149010
KOⁱ	K09216
OMAⁱ	FTTGTCN
OrthoDBⁱ	EOG091G0LB1

Gene expression databases

Bgeeⁱ	ENSRNOG00000006850 Expressed in 5 organ(s), highest expression level in colon

Bgeeⁱ

ENSRNOG00000006850 Expressed in 5 organ(s), highest expression level in colon

Family and domain databases

InterProⁱ	View protein in InterPro IPR027756 Ovo-like IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
PANTHERⁱ	PTHR10032 PTHR10032, 1 hit
Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 2 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 4 hits
SUPFAMⁱ	SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 2 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	D4A5U5_RAT
Accessionⁱ	D4A5U5Primary (citable) accession number: D4A5U5
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 20, 2010
	Last sequence update:	April 20, 2010
	Last modified:	November 7, 2018
	This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - D4A5U5 (D4A5U5_RAT)

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Ovo-like zinc finger 2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ