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Protein
Submitted name:

Transcription factor AP-2 beta

Gene

Tfap2b

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-8866904 Negative regulation of activity of TFAP2 (AP-2) family transcription factors
R-RNO-8866907 Activation of the TFAP2 (AP-2) family of transcription factors

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor AP-2 betaImported
Gene namesi
Name:Tfap2bImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 9

Organism-specific databases

RGDi1306321 Tfap2b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiD4A505
PRIDEiD4A505

Expressioni

Gene expression databases

BgeeiENSRNOG00000011823 Expressed in 3 organ(s), highest expression level in adult mammalian kidney
ExpressionAtlasiD4A505 baseline and differential

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000030726

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini230 – 424TF_AP-2InterPro annotationAdd BLAST195

Phylogenomic databases

eggNOGiKOG3811 Eukaryota
ENOG410XR9E LUCA
GeneTreeiENSGT00550000074577
InParanoidiD4A505
KOiK09176
TreeFamiTF313718

Family and domain databases

InterProiView protein in InterPro
IPR004979 TF_AP2
IPR008122 TF_AP2_beta
IPR013854 TF_AP2_C
PANTHERiPTHR10812 PTHR10812, 1 hit
PTHR10812:SF14 PTHR10812:SF14, 1 hit
PfamiView protein in Pfam
PF03299 TF_AP-2, 1 hit
PRINTSiPR01750 AP2BTNSCPFCT
PR01748 AP2TNSCPFCT

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

D4A505-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHSPPRDQAA IMLWKLVENV KYEDIYEDRH DGVPSHSSRL SQLGSVSQGP
60 70 80 90 100
YSSAPPLSHT PSSDFQPPYF PPPYQPLPYH QSQDPYSHVN DPYSLNPLHQ
110 120 130 140 150
PQQHPWGQRQ RQEVGSEAGS LLPQPRAALP QLSGLDPRRD YHSVRRPDVL
160 170 180 190 200
LHSAHHGLDA GMGDSLSLHG LGHPGMEDVQ SVEDANNSGM NLLDQSVIKK
210 220 230 240 250
VPVPPKSVTS LMMNKDGFLG GMSVNTGEVF CSVPGRLSLL SSTSKYKVTV
260 270 280 290 300
GEVQRRLSPP ECLNASLLGG VLRRAKSKNG GRSLRERLEK IGLNLPAGRR
310 320 330 340 350
KAANVTLLTS LVEGEAVHLA RDFGYICETE FPAKAVSEYL NRQHTDPSDL
360 370 380 390 400
HSRKNMLLAT KQLCKEFTDL LAQDRTPIGN SRPSPILEPG IQSCLTHFSL
410 420 430 440 450
ITHGFGAPAI CAALTALQNY LTEALKGMDK MFLNNTTNRH TSGEGPGQRA

PRV
Length:453
Mass (Da):49,656
Last modified:April 20, 2010 - v1
Checksum:iA9003278C0A031FB
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2KAT2A0A0G2KAT2_RAT
Transcription factor AP-2 beta
Tfap2b
459Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07067001 Genomic DNA No translation available.
RefSeqiNP_001100366.2, NM_001106896.2
UniGeneiRn.12263

Genome annotation databases

EnsembliENSRNOT00000030912; ENSRNOP00000030726; ENSRNOG00000011823
GeneIDi301285
KEGGirno:301285

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07067001 Genomic DNA No translation available.
RefSeqiNP_001100366.2, NM_001106896.2
UniGeneiRn.12263

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000030726

Proteomic databases

PaxDbiD4A505
PRIDEiD4A505

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000030912; ENSRNOP00000030726; ENSRNOG00000011823
GeneIDi301285
KEGGirno:301285

Organism-specific databases

CTDi7021
RGDi1306321 Tfap2b

Phylogenomic databases

eggNOGiKOG3811 Eukaryota
ENOG410XR9E LUCA
GeneTreeiENSGT00550000074577
InParanoidiD4A505
KOiK09176
TreeFamiTF313718

Enzyme and pathway databases

ReactomeiR-RNO-8866904 Negative regulation of activity of TFAP2 (AP-2) family transcription factors
R-RNO-8866907 Activation of the TFAP2 (AP-2) family of transcription factors

Gene expression databases

BgeeiENSRNOG00000011823 Expressed in 3 organ(s), highest expression level in adult mammalian kidney
ExpressionAtlasiD4A505 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR004979 TF_AP2
IPR008122 TF_AP2_beta
IPR013854 TF_AP2_C
PANTHERiPTHR10812 PTHR10812, 1 hit
PTHR10812:SF14 PTHR10812:SF14, 1 hit
PfamiView protein in Pfam
PF03299 TF_AP-2, 1 hit
PRINTSiPR01750 AP2BTNSCPFCT
PR01748 AP2TNSCPFCT
ProtoNetiSearch...

Entry informationi

Entry nameiD4A505_RAT
AccessioniPrimary (citable) accession number: D4A505
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 7, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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