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Protein
Submitted name:

Lipoxygenase homology domains 1

Gene

Loxhd1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Lipoxygenase homology domains 1Imported
Gene namesi
Name:Loxhd1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 18

Organism-specific databases

RGDi1304815 Loxhd1

Subcellular locationi

PTM / Processingi

Proteomic databases

PaxDbiD4A3A1
PRIDEiD4A3A1

Expressioni

Gene expression databases

BgeeiENSRNOG00000017410 Expressed in 1 organ(s), highest expression level in brain

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000023487

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 160PLATInterPro annotationAdd BLAST118
Domaini172 – 287PLATInterPro annotationAdd BLAST116
Domaini296 – 412PLATInterPro annotationAdd BLAST117
Domaini425 – 540PLATInterPro annotationAdd BLAST116
Domaini553 – 673PLATInterPro annotationAdd BLAST121
Domaini684 – 803PLATInterPro annotationAdd BLAST120
Domaini814 – 929PLATInterPro annotationAdd BLAST116
Domaini1026 – 1144PLATInterPro annotationAdd BLAST119
Domaini1180 – 1298PLATInterPro annotationAdd BLAST119
Domaini1311 – 1436PLATInterPro annotationAdd BLAST126
Domaini1465 – 1583PLATInterPro annotationAdd BLAST119
Domaini1701 – 1816PLATInterPro annotationAdd BLAST116
Domaini1828 – 1946PLATInterPro annotationAdd BLAST119
Domaini1959 – 2080PLATInterPro annotationAdd BLAST122
Domaini2097 – 2213PLATInterPro annotationAdd BLAST117

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili917 – 949Sequence analysisAdd BLAST33
Coiled coili961 – 982Sequence analysisAdd BLAST22

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IJEB Eukaryota
ENOG410XTDU LUCA
GeneTreeiENSGT00390000018830
InParanoidiD4A3A1
OMAiNSKIHIV
OrthoDBiEOG091G00F7
TreeFamiTF350466

Family and domain databases

Gene3Di2.40.180.10, 13 hits
InterProiView protein in InterPro
IPR037060 Catalase_core_sf
IPR001024 PLAT/LH2_dom
IPR036392 PLAT/LH2_dom_sf
PfamiView protein in Pfam
PF01477 PLAT, 15 hits
SMARTiView protein in SMART
SM00308 LH2, 14 hits
SUPFAMiSSF49723 SSF49723, 16 hits
PROSITEiView protein in PROSITE
PS50095 PLAT, 15 hits

Sequencei

Sequence statusi: Complete.

D4A3A1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMPQKKKRRK KDIDFLGLYE EELLNYNSED DEDELEHEYY KAKVYEVVTA
60 70 80 90 100
TGDVRGAGTD ANVFITIFGE NGLSPKLHLT SKSESAFEKA NVDVFRVRTN
110 120 130 140 150
NVGLIYKIRI EHDNTGLNAS WYLDRVIVTD MKRPHLRYYF NCNNWLSKVE
160 170 180 190 200
GDRQWCRDLL ASFDPMDMPR GNKYEIKVYT GDVIGAGTDA DVFINIFGEY
210 220 230 240 250
GDTGERRLEN EKDNFEKGAE DKFTLDAPDL GQLMKINVGH NNKGGSAGWF
260 270 280 290 300
LSKIIIEDIG NKRKYDFPLN RWLALDEDDG KIQRDILVGG AETTAITYIV
310 320 330 340 350
TVFTGDIRGA GTKSKIYLVM YGARGNRNSG KIFLEGGVFD RGRTDIFHID
360 370 380 390 400
LAVLLSPLSR VSIGHGNIGV NRGWYCEKVV VLCPFTGIQQ TFPCSNWLDE
410 420 430 440 450
KKADGLIERQ LYEMVSLRKK RLKKFPWSLW VWTTDLKKAG TNSPIFIQIY
460 470 480 490 500
GKKGRTDEIL LNPNNKWFKP GIIEKFRMEL PDLGGFYKIR AWHDRQNPGS
510 520 530 540 550
GWHLEKMTLM NTLNKDKYNF NCNRWLDANE DDNEIVREMT AEGPTVRRIM
560 570 580 590 600
GMARYRVTVC TGELEGAGTD ANVYLCLFGD VGDTGERLLY NCRNNTDLFE
610 620 630 640 650
KGNADEFTIE SVTMRKVRRV RVRHDGKGSG SGWYLDRVLV REEGQPESDN
660 670 680 690 700
VEFPCLRWLD KDKDDGQLVR ELLPSDSNAT LKNFRYHISV KTGDVSGAST
710 720 730 740 750
DSRVYIKLYG EKSDTIKQVL LVSDNNLKDY FERGRVDEFT LETLNIGTII
760 770 780 790 800
RLVIGHDSTG MHAGWFLGSV QIRVPRQGKQ YTFPANRWLD KNQADGRLEV
810 820 830 840 850
ELYPSEVVEI QKLVHYEIEI WTGDVGGAGT TSRVYVQIYG EEGKTEVLFL
860 870 880 890 900
SSRSKVFDRG SKDIFQLEAA DVGEIYKIRL GHTGEGFGPS WFVDTVWLRH
910 920 930 940 950
LVVQEESLTP EEEARRKKEK EKLRQLLKKE RLKAKLQRKK KKKKKGSDEE
960 970 980 990 1000
EEGDEEEESS SEESSSEEEE EEESEEEEEE EEYGPGMQEV IVQYKFVANR
1010 1020 1030 1040 1050
WLARGKEDNE LVVELVPAGQ PGPEPNTYEV QVITGNVPKA GTDANVYLTI
1060 1070 1080 1090 1100
YGEEYGDTGE RPLKKSDKSN KFEQGQTDTF TIYAIDLGAL TKIRIRHDNT
1110 1120 1130 1140 1150
GNRPGWFLDR IDITDVNNET TYYFPCQRWL AVEEDDGQLS RELLPVDESY
1160 1170 1180 1190 1200
VLPSEDEEGG GQGDNNPLDN LALEQKDKST TFSVTIKTGD KKNAGTDANV
1210 1220 1230 1240 1250
FITLFGTKDN NGMTLLKSSK TNSDKFERDS IEIFTVETLD LGDLWKVRIG
1260 1270 1280 1290 1300
HDNTGKAPGW FVDWVEVDAP SLGKCMTFPC GRWLAKNEDD GSIVRDLFHA
1310 1320 1330 1340 1350
ELQTRLYTPF VPYEITLYTS DVFAAGTDAN VFIVIYGCDA VCTRQKFLCT
1360 1370 1380 1390 1400
NKREQKLLFE RKSASRFIVE LEDVGEIIEK IRIGHDNTGI NPGWHCSHVD
1410 1420 1430 1440 1450
IRRLLPEKDG TETLTFPCDR WLATSEDDKK TIRELVPYDI FTEKYMKDGS
1460 1470 1480 1490 1500
LRQVYKEVEE PLDIVLYSVQ IFTGNVPGAG TDAKVYITIY GDLGDTGERY
1510 1520 1530 1540 1550
LGKSENRTNK FEKGTADTFI IEAADLGVIY KIKLRHDNTK WCADWYVEKV
1560 1570 1580 1590 1600
EIWNDTNEDE FLFLCGRWLS LKKEDGRLER LFYEKEYTGD RSSNCSSPAD
1610 1620 1630 1640 1650
FWEIALSSKM ADVDIDTVTG PMVDYVQDGP VIPYYVSVTT GKHKEAATDS
1660 1670 1680 1690 1700
RAFVLLIGED DERTNRIWLD FPQGKRGFSC GSVEEFYVGG LDVGIIKKIE
1710 1720 1730 1740 1750
VLYEMTVWTG DVVGGGTDSN IFMTLYGING STEEVQLDKK KARFEREQND
1760 1770 1780 1790 1800
TFIMEILDIA PFTKMRIRID GLGSRPEWFL ERILLKNMNT GDLTMFYYGD
1810 1820 1830 1840 1850
WLSQKKGKKT LVCEICAVID GEEMMEWTSY TVSVKTSDIL GAGTDANVFI
1860 1870 1880 1890 1900
IIFGENGDSG TLALKQSANW NKFERNNTDT FNFPDMLSLG HLCKLRVWHD
1910 1920 1930 1940 1950
NKGIFPGWHL SYIDVKDNSR DETFRFQCDC WLSKSEGDRQ TLRDFACANN
1960 1970 1980 1990 2000
EIRDELEETT YEIVIETGNG GETRENIWLI LEGRKNRSKE FLVENSSRQR
2010 2020 2030 2040 2050
AFRKGTTDTF EFDSIFLGDI ASLCVGHLAR EDRFIPKREL VWHVKTITIT
2060 2070 2080 2090 2100
EMEYGNVYFF NCDCLIPLKR KRKYFKVFEV TKTTESFASK IQSLVPVKYE
2110 2120 2130 2140 2150
VIVTTGYEPG AGTDANVFVT IFGANGDTGK RELKQKMRNL FERGSTDRFF
2160 2170 2180 2190 2200
LETLELGELR KVRLEHDSSG YYSGWLVEKV EVTNTSTGVA TIFSCGRWLD
2210
KSRGDGLTWR ELFPSV
Length:2,216
Mass (Da):253,061
Last modified:July 22, 2015 - v3
Checksum:i7BE87B473A324214
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07032608 Genomic DNA No translation available.
AABR07032609 Genomic DNA No translation available.
AABR07032610 Genomic DNA No translation available.
AABR07032611 Genomic DNA No translation available.
AABR07032612 Genomic DNA No translation available.
AABR07032613 Genomic DNA No translation available.
AABR07032614 Genomic DNA No translation available.
AABR07032615 Genomic DNA No translation available.
AABR07072614 Genomic DNA No translation available.
AC139391 Genomic DNA No translation available.
RefSeqiNP_001099602.3, NM_001106132.3

Genome annotation databases

EnsembliENSRNOT00000023487; ENSRNOP00000023487; ENSRNOG00000017410
GeneIDi291427
KEGGirno:291427

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07032608 Genomic DNA No translation available.
AABR07032609 Genomic DNA No translation available.
AABR07032610 Genomic DNA No translation available.
AABR07032611 Genomic DNA No translation available.
AABR07032612 Genomic DNA No translation available.
AABR07032613 Genomic DNA No translation available.
AABR07032614 Genomic DNA No translation available.
AABR07032615 Genomic DNA No translation available.
AABR07072614 Genomic DNA No translation available.
AC139391 Genomic DNA No translation available.
RefSeqiNP_001099602.3, NM_001106132.3

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000023487

Proteomic databases

PaxDbiD4A3A1
PRIDEiD4A3A1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000023487; ENSRNOP00000023487; ENSRNOG00000017410
GeneIDi291427
KEGGirno:291427

Organism-specific databases

CTDi125336
RGDi1304815 Loxhd1

Phylogenomic databases

eggNOGiENOG410IJEB Eukaryota
ENOG410XTDU LUCA
GeneTreeiENSGT00390000018830
InParanoidiD4A3A1
OMAiNSKIHIV
OrthoDBiEOG091G00F7
TreeFamiTF350466

Gene expression databases

BgeeiENSRNOG00000017410 Expressed in 1 organ(s), highest expression level in brain

Family and domain databases

Gene3Di2.40.180.10, 13 hits
InterProiView protein in InterPro
IPR037060 Catalase_core_sf
IPR001024 PLAT/LH2_dom
IPR036392 PLAT/LH2_dom_sf
PfamiView protein in Pfam
PF01477 PLAT, 15 hits
SMARTiView protein in SMART
SM00308 LH2, 14 hits
SUPFAMiSSF49723 SSF49723, 16 hits
PROSITEiView protein in PROSITE
PS50095 PLAT, 15 hits
ProtoNetiSearch...

Entry informationi

Entry nameiD4A3A1_RAT
AccessioniPrimary (citable) accession number: D4A3A1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: November 7, 2018
This is version 58 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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