Neurog2

Functionⁱ

GO - Molecular functionⁱ

protein dimerization activity Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

neuron differentiation Source: InterPro
regulation of transcription, DNA-templated Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Neurogenin 2Imported Submitted name: RCG28897Imported
Gene namesⁱ	Name:Neurog2Imported ORF Names:rCG_28897Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 2

Organism-specific databases

Rat genome database More...RGDⁱ	1309061 Neurog2

RGDⁱ

1309061 Neurog2

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000010972 Expressed in 1 organ(s), highest expression level in brain

Bgeeⁱ

ENSRNOG00000010972 Expressed in 1 organ(s), highest expression level in brain

Interactionⁱ

GO - Molecular functionⁱ

protein dimerization activity Source: InterPro

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000014570

STRINGⁱ

10116.ENSRNOP00000014570

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	112 – 164	BHLHInterPro annotationAdd BLAST		53

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	118 – 138	Sequence analysisAdd BLAST		21

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	ENOG410IQ4B Eukaryota ENOG410XZ4C LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00680000099860
KEGG Orthology (KO) More...KOⁱ	K09082
OMAⁱ	SDMDYWQ
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0PNH
TreeFamⁱ	TF315153

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00083 HLH, 1 hit
Gene3Dⁱ	4.10.280.10, 1 hit
InterProⁱ	View protein in InterPro IPR011598 bHLH_dom IPR036638 HLH_DNA-bd_sf IPR032655 Ngn2
PANTHERⁱ	PTHR19290:SF105 PTHR19290:SF105, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00010 HLH, 1 hit
SMARTⁱ	View protein in SMART SM00353 HLH, 1 hit
SUPFAMⁱ	SSF47459 SSF47459, 1 hit
PROSITEⁱ	View protein in PROSITE PS50888 BHLH, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

D4A2E3-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MFVKSETLEL KEEEEVLMLL GSASPASATL TPMSSSADEE EDEELRRPGA 
        60         70         80         90        100
ARGQRGAEAG QGVQGSSASG AGGCRPGRLL GLVHECKRRP SRARAVSRGA 
       110        120        130        140        150
KTAETVQRIK KTRRLKANNR ERNRMHNLNA ALDALREVLP TFPEDAKLTK 
       160        170        180        190        200
IETLRFAHNY IWALTETLRL ADHCAGGGSL QGALFSEAVL LSPGAALGAS 
       210        220        230        240        250
GDSPSPSSSW SCTNSPASSS NSTSPYSCTL SPASPGSDVD YWQPPPPEKH 
       260 
RYAPHLPLAR DCI

Length:263

Mass (Da):28,061

Last modified:April 20, 2010 - v1

Checksum:ⁱ03A2057A6287DB94

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07013288 Genomic DNA No translation available. CH473952 Genomic DNA Translation: EDL82153.1
NCBI Reference Sequences More...RefSeqⁱ	XP_008759703.1, XM_008761481.2 XP_008773484.1, XM_008775262.2

Genome annotation databases

Ensemblⁱ	ENSRNOT00000014570; ENSRNOP00000014570; ENSRNOG00000010972
GeneIDⁱ	295475
KEGGⁱ	rno:295475
UCSC genome browser More...UCSCⁱ	RGD:1309061 rat

Protein	Similar proteins		Species	Score	Length	Source
D4A2E3	Neurogenin-2		MOUSE		263	UniRef90_P70447
Uncharacterized protein		NEOLE		284
neurogenin-2		MESAU		267
UPI000B4F57D6		MERUN		269
UPI00042AF5CD		PERMB		267
+5

Protein	Similar proteins		Species	Score	Length	Source
D4A2E3	Neurogenin-2		MOUSE		263	UniRef50_P70447
Neurogenin-2		HUMAN		272
Uncharacterized protein		NEOLE		284
neurogenin-2		MESAU		267
Uncharacterized protein		AOTNA		272
+87

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07013288 Genomic DNA No translation available. CH473952 Genomic DNA Translation: EDL82153.1
RefSeqⁱ	XP_008759703.1, XM_008761481.2 XP_008773484.1, XM_008775262.2

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000014570

STRINGⁱ

10116.ENSRNOP00000014570

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000014570; ENSRNOP00000014570; ENSRNOG00000010972
GeneIDⁱ	295475
KEGGⁱ	rno:295475
UCSCⁱ	RGD:1309061 rat

Organism-specific databases

CTDⁱ	63973
RGDⁱ	1309061 Neurog2

Phylogenomic databases

eggNOGⁱ	ENOG410IQ4B Eukaryota ENOG410XZ4C LUCA
GeneTreeⁱ	ENSGT00680000099860
KOⁱ	K09082
OMAⁱ	SDMDYWQ
OrthoDBⁱ	EOG091G0PNH
TreeFamⁱ	TF315153

Gene expression databases

Bgeeⁱ	ENSRNOG00000010972 Expressed in 1 organ(s), highest expression level in brain

Bgeeⁱ

ENSRNOG00000010972 Expressed in 1 organ(s), highest expression level in brain

Family and domain databases

CDDⁱ	cd00083 HLH, 1 hit
Gene3Dⁱ	4.10.280.10, 1 hit
InterProⁱ	View protein in InterPro IPR011598 bHLH_dom IPR036638 HLH_DNA-bd_sf IPR032655 Ngn2
PANTHERⁱ	PTHR19290:SF105 PTHR19290:SF105, 1 hit
Pfamⁱ	View protein in Pfam PF00010 HLH, 1 hit
SMARTⁱ	View protein in SMART SM00353 HLH, 1 hit
SUPFAMⁱ	SSF47459 SSF47459, 1 hit
PROSITEⁱ	View protein in PROSITE PS50888 BHLH, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	D4A2E3_RAT
Accessionⁱ	D4A2E3Primary (citable) accession number: D4A2E3
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 20, 2010
	Last sequence update:	April 20, 2010
	Last modified:	September 12, 2018
	This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - D4A2E3 (D4A2E3_RAT)

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Neurogenin 2

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Organism-specific databases

Expressionⁱ

Gene expression databases

Interactionⁱ

GO - Molecular functionⁱ

Protein-protein interaction databases

Family & Domainsⁱ

Domains and Repeats

Coiled coil

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProt is an ELIXIR core data resource

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - D4A2E3 (D4A2E3_RAT)

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Neurogenin 2

Neurog2

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ