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Entry version 58 (16 Jan 2019)
Sequence version 1 (20 Apr 2010)
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Protein
Submitted name:

Proline and serine-rich 1

Gene

Proser1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Proline and serine-rich 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Proser1Imported
Synonyms:RGD1309403_predictedImported
ORF Names:rCG_50046Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Rat genome database

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RGDi
1309403 Proser1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
D4A1X9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSRNOG00000010980 Expressed in 9 organ(s), highest expression level in spleen

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 61DUF4476InterPro annotationAdd BLAST61
Domaini32 – 121DUF4476InterPro annotationAdd BLAST90

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IE75 Eukaryota
ENOG410ZVUA LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00730000111188

Identification of Orthologs from Complete Genome Data

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OMAi
KCYTPSA

Database of Orthologous Groups

More...
OrthoDBi
395841at2759

TreeFam database of animal gene trees

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TreeFami
TF331494

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR028011 DUF4476

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14771 DUF4476, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D4A1X9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDKKSFETVL DEIRKAVLTE YKLKAIEYVH GYFSSEQVVD LLRYFSWAEP
60 70 80 90 100
QLKAMKALQH KMVAVHPAEV VSILSCFTFS KDKLAALELL ASNIVDAQNS
110 120 130 140 150
RPIEDLFRIN MSEKKRCKRV LEQASKAGCK APHAMISSCG TIPGNPYPKG
160 170 180 190 200
KPSRINGIFP GTPLKKDGEE ITNEGKGIAA RILGPSKPPP STYNPHKPVP
210 220 230 240 250
YPIPPCRPHA TIAPSAYNNA GLVPLANVIA PGVPPPPPYT PNPAGADNED
260 270 280 290 300
LSSQSKPTQS QTFSTAASQL FSPHGSNPST PAATPVPAVS PAKAVNHPSV
310 320 330 340 350
SAAATGAGMS APNTPLAVFP TPQPSTPNPT VIRTPSVPAT PVTSTHSTTP
360 370 380 390 400
APVPSVFSGL VPLPGLSATP TPSTQAISIP RVTLASSETF ASTCAPFTSH
410 420 430 440 450
SLASSTAGSA SNPITAPLSS VFAGLPLPFP PASHSIATPT PSVIASATGP
460 470 480 490 500
LGVNSPLLSA LKGFLTSNDT HLINSSGLPS AVTSGLASLS SLPSRNSDSP
510 520 530 540 550
ASVTNKCYPP AAVPTAQRSS TPGLAMFPGL QSPVASATSA APTLPAQSPL
560 570 580 590 600
VTPSSTAVPV SCGSSGSLLH GPHAGGISSV PAAATMPVMI KSEPTSPPPS
610 620 630 640 650
AFKGPAHPGT PAHGTLGLSG ALGRGYPTTS VPISVPTCLN PALSGLSSLS
660 670 680 690 700
TPLAGSMSLT PHASSTPIAP VFTALPPFTS LTNSFPLPGS PSLNPAVSLT
710 720 730 740 750
GPSTTTSAAV HPSSATVRTV LPTTNSSPAA FPLNLSTAVP SLFAVTQGPL
760 770 780 790 800
PTSNPSYPGF PVSSAPSGAP TLPSFPGLQA PSTVAVTPLP VAASAPSPAP
810 820 830 840 850
VLPGFASAFS SNFNSALVAQ AGLSSGLQAA GSSVFPGLLS LPGIPGFSQT
860 870 880 890 900
PPQSSLQELQ HSAAAQSALL QQVHSASALE NYPAQTDGFP SYPSTPGTPF
910
SLQTGLSQSG WQ
Length:912
Mass (Da):92,021
Last modified:April 20, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBEDDCFEC963CDB02
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AABR07010601 Genomic DNA No translation available.
CH474003 Genomic DNA Translation: EDM14951.1

NCBI Reference Sequences

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RefSeqi
NP_001101146.1, NM_001107676.1

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Rn.38949

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000014614; ENSRNOP00000014614; ENSRNOG00000010980

Database of genes from NCBI RefSeq genomes

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GeneIDi
310417

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
rno:310417

UCSC genome browser

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UCSCi
RGD:1309403 rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07010601 Genomic DNA No translation available.
CH474003 Genomic DNA Translation: EDM14951.1
RefSeqiNP_001101146.1, NM_001107676.1
UniGeneiRn.38949

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

Proteomic databases

jPOSTiD4A1X9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000014614; ENSRNOP00000014614; ENSRNOG00000010980
GeneIDi310417
KEGGirno:310417
UCSCiRGD:1309403 rat

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80209
RGDi1309403 Proser1

Phylogenomic databases

eggNOGiENOG410IE75 Eukaryota
ENOG410ZVUA LUCA
GeneTreeiENSGT00730000111188
OMAiKCYTPSA
OrthoDBi395841at2759
TreeFamiTF331494

Gene expression databases

BgeeiENSRNOG00000010980 Expressed in 9 organ(s), highest expression level in spleen

Family and domain databases

InterProiView protein in InterPro
IPR028011 DUF4476
PfamiView protein in Pfam
PF14771 DUF4476, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD4A1X9_RAT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D4A1X9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: January 16, 2019
This is version 58 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
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