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Protein
Submitted name:

Intraflagellar transport 57

Gene

Ift57

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-5610787 Hedgehog 'off' state
R-RNO-5620924 Intraflagellar transport
R-RNO-5632684 Hedgehog 'on' state

Names & Taxonomyi

Protein namesi
Submitted name:
Intraflagellar transport 57Imported
Submitted name:
Intraflagellar transport 57 homolog (Chlamydomonas) (Predicted)Imported
Gene namesi
Name:Ift57Imported
Synonyms:Ift57_predictedImported
ORF Names:rCG_52737Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 11

Organism-specific databases

RGDi1305947 Ift57

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium, FlagellumImported

PTM / Processingi

Proteomic databases

PRIDEiD4A1V1

Expressioni

Gene expression databases

BgeeiENSRNOG00000001958 Expressed in 9 organ(s), highest expression level in testis

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000002684

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili311 – 331Sequence analysisAdd BLAST21
Coiled coili339 – 366Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0972 Eukaryota
ENOG410XT77 LUCA
GeneTreeiENSGT00390000006307
KOiK04638
OMAiVHAHDQD
OrthoDBiEOG091G0GDF
TreeFamiTF106156

Family and domain databases

InterProiView protein in InterPro
IPR019530 Intra-flagellar_transport_57
PANTHERiPTHR16011 PTHR16011, 1 hit
PfamiView protein in Pfam
PF10498 IFT57, 1 hit

Sequencei

Sequence statusi: Complete.

D4A1V1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAAAAVIPP SGLDDGVSRA RGEGAGEAVV ERGPGAAYHM FVVMEDLVEK
60 70 80 90 100
LKLLRYEEEL LRKSNLKPPS RHYFALPTNP GEQFYMFCTL AAWLINKTGR
110 120 130 140 150
AFEQPQEYDD PNATISNILS ELRSFGRTAD FPPSKLKSGY GEHVCYVLDC
160 170 180 190 200
LAEEALKYIG FTWKRPSYPV EELEEETVPE DDAELTLSKV DEEFVEEETD
210 220 230 240 250
NEENFIDLNV LKAQTYRLDT NESAKQEDIL ESTTDAAEWS LEVERVLPQL
260 270 280 290 300
KVTIRTDNKD WRIHVDQMHQ HKSGIESALK ETKGFLDKLH NEISRTLEKI
310 320 330 340 350
GSREKYINNQ LEHLVQEYRG AQAQLSEARE RYQQGNGGVT ERTRLLSEVT
360 370 380 390 400
EELEKVKQEM EEKGSSMTDG TPLVKIKQSL TKLKQETVQM DIRIGVVEHT
410 420
LLQSKLKEKC NMTRDMHAAV TPESAIGFY
Length:429
Mass (Da):48,781
Last modified:April 20, 2010 - v1
Checksum:i9660EE195F604F8C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07034113 Genomic DNA No translation available.
AABR07034114 Genomic DNA No translation available.
AABR07034115 Genomic DNA No translation available.
CH473967 Genomic DNA Translation: EDM11101.1
RefSeqiNP_001100563.1, NM_001107093.1
UniGeneiRn.63846

Genome annotation databases

EnsembliENSRNOT00000002684; ENSRNOP00000002684; ENSRNOG00000001958
GeneIDi303968
KEGGirno:303968
UCSCiRGD:1305947 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07034113 Genomic DNA No translation available.
AABR07034114 Genomic DNA No translation available.
AABR07034115 Genomic DNA No translation available.
CH473967 Genomic DNA Translation: EDM11101.1
RefSeqiNP_001100563.1, NM_001107093.1
UniGeneiRn.63846

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000002684

Proteomic databases

PRIDEiD4A1V1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000002684; ENSRNOP00000002684; ENSRNOG00000001958
GeneIDi303968
KEGGirno:303968
UCSCiRGD:1305947 rat

Organism-specific databases

CTDi55081
RGDi1305947 Ift57

Phylogenomic databases

eggNOGiKOG0972 Eukaryota
ENOG410XT77 LUCA
GeneTreeiENSGT00390000006307
KOiK04638
OMAiVHAHDQD
OrthoDBiEOG091G0GDF
TreeFamiTF106156

Enzyme and pathway databases

ReactomeiR-RNO-5610787 Hedgehog 'off' state
R-RNO-5620924 Intraflagellar transport
R-RNO-5632684 Hedgehog 'on' state

Gene expression databases

BgeeiENSRNOG00000001958 Expressed in 9 organ(s), highest expression level in testis

Family and domain databases

InterProiView protein in InterPro
IPR019530 Intra-flagellar_transport_57
PANTHERiPTHR16011 PTHR16011, 1 hit
PfamiView protein in Pfam
PF10498 IFT57, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD4A1V1_RAT
AccessioniPrimary (citable) accession number: D4A1V1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 7, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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