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Protein
Submitted name:

SPC24, NDC80 kinetochore complex component

Gene

Spc24

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Enzyme and pathway databases

ReactomeiR-RNO-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-RNO-2467813 Separation of Sister Chromatids
R-RNO-2500257 Resolution of Sister Chromatid Cohesion
R-RNO-5663220 RHO GTPases Activate Formins
R-RNO-68877 Mitotic Prometaphase

Names & Taxonomyi

Protein namesi
Submitted name:
SPC24, NDC80 kinetochore complex componentImported
Gene namesi
Name:Spc24Imported
Synonyms:Spc24-ps1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi1307631 Spc24

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiD4A1C5

Expressioni

Gene expression databases

BgeeiENSRNOG00000029862 Expressed in 9 organ(s), highest expression level in testis

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000045819

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili80 – 131Sequence analysisAdd BLAST52

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IYQI Eukaryota
ENOG4111TPD LUCA
GeneTreeiENSGT00390000005584
InParanoidiD4A1C5
KOiK11549
OMAiGMVKGIH
OrthoDBiEOG091G0N4A
TreeFamiTF333217

Family and domain databases

InterProiView protein in InterPro
IPR013252 Ndc80_Spc24
PANTHERiPTHR22142 PTHR22142, 1 hit
PfamiView protein in Pfam
PF08286 Spc24, 1 hit

Sequencei

Sequence statusi: Complete.

D4A1C5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAFRDMEEV SYGLLSLLAA NRAEAQQRRL LGRHEQMVER LLEMQDGADR
60 70 80 90 100
QLRETLAVEE EVAQSLLELK ECTRLGGTEL QQLEVELQKA SKEDSCLQAR
110 120 130 140 150
LCQLTAELQE LREMEEDLQR QERDVDEDNT VTIPSAVYVA QLYHQISKIE
160 170 180 190
WDYECEPGMV KGIHHGPSVA QPIHLDSAQL SQKFISDYLW SLVDTAW
Length:197
Mass (Da):22,615
Last modified:July 22, 2015 - v3
Checksum:i1471D0E37983C15D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC119556 Genomic DNA No translation available.
RefSeqiXP_003750496.3, XM_003750448.4
XP_003754424.3, XM_003754376.4

Genome annotation databases

EnsembliENSRNOT00000045384; ENSRNOP00000045819; ENSRNOG00000029862
GeneIDi363028
KEGGirno:363028

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC119556 Genomic DNA No translation available.
RefSeqiXP_003750496.3, XM_003750448.4
XP_003754424.3, XM_003754376.4

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000045819

Proteomic databases

PaxDbiD4A1C5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000045384; ENSRNOP00000045819; ENSRNOG00000029862
GeneIDi363028
KEGGirno:363028

Organism-specific databases

CTDi147841
RGDi1307631 Spc24

Phylogenomic databases

eggNOGiENOG410IYQI Eukaryota
ENOG4111TPD LUCA
GeneTreeiENSGT00390000005584
InParanoidiD4A1C5
KOiK11549
OMAiGMVKGIH
OrthoDBiEOG091G0N4A
TreeFamiTF333217

Enzyme and pathway databases

ReactomeiR-RNO-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-RNO-2467813 Separation of Sister Chromatids
R-RNO-2500257 Resolution of Sister Chromatid Cohesion
R-RNO-5663220 RHO GTPases Activate Formins
R-RNO-68877 Mitotic Prometaphase

Gene expression databases

BgeeiENSRNOG00000029862 Expressed in 9 organ(s), highest expression level in testis

Family and domain databases

InterProiView protein in InterPro
IPR013252 Ndc80_Spc24
PANTHERiPTHR22142 PTHR22142, 1 hit
PfamiView protein in Pfam
PF08286 Spc24, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD4A1C5_RAT
AccessioniPrimary (citable) accession number: D4A1C5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: September 12, 2018
This is version 51 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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