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Protein

tRNA dimethylallyltransferase

Gene

Trit1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.UniRule annotation

Catalytic activityi

Dimethylallyl diphosphate + adenine(37) in tRNA = diphosphate + N6-dimethylallyladenine(37) in tRNA.UniRule annotation

GO - Molecular functioni

  • ATP binding Source: UniProtKB-UniRule
  • metal ion binding Source: UniProtKB-KW
  • tRNA dimethylallyltransferase activity Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationImported
Biological processtRNA processingUniRule annotation
LigandATP-bindingUniRule annotation, Metal-binding, Nucleotide-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA dimethylallyltransferaseUniRule annotation (EC:2.5.1.75UniRule annotation)
Gene namesi
Name:Trit1Imported
Synonyms:Trit1_predictedImported
ORF Names:rCG_30895Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi1304781 Trit1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiD4A175

Expressioni

Gene expression databases

BgeeiENSRNOG00000014274 Expressed in 10 organ(s), highest expression level in colon

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019587

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini407 – 431zf-C2H2_jazInterPro annotationAdd BLAST25

Sequence similaritiesi

Belongs to the IPP transferase family.UniRule annotation

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG1384 Eukaryota
COG0324 LUCA
GeneTreeiENSGT00390000015214
KOiK00791
OMAiCQHHMIS
OrthoDBiEOG091G0VY8
TreeFamiTF315069

Family and domain databases

HAMAPiMF_00185 IPP_trans, 1 hit
InterProiView protein in InterPro
IPR039657 Dimethylallyltransferase
IPR030666 IPP_transferase_euk
IPR018022 IPT
IPR027417 P-loop_NTPase
IPR022755 Znf_C2H2_jaz
IPR036236 Znf_C2H2_sf
PANTHERiPTHR11088 PTHR11088, 1 hit
PfamiView protein in Pfam
PF01715 IPPT, 1 hit
PF12171 zf-C2H2_jaz, 1 hit
PIRSFiPIRSF039110 IPP_transferase, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF57667 SSF57667, 1 hit
TIGRFAMsiTIGR00174 miaA, 1 hit

Sequencei

Sequence statusi: Complete.

D4A175-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAAAAARAV PVSSGFRGLP RTLPLVVILG ATGTGKSTLA LQLGQRLGGE
60 70 80 90 100
IVSADSMQVY EGLDIITNKV SAQEQKMCRH HMISFVDPLV TSYTVVDFRN
110 120 130 140 150
RATALISLRK LSTHPWRVPS GDIFARDKIP IVVGGTNYYI ESLLWKVLVT
160 170 180 190 200
TKPQGMGTGK AVDRKVELEK EDGHELHKRL SQVDPEMAAK LHPHDKRKVA
210 220 230 240 250
RSLQVFEETG VSHSEFLHRQ HAEEGGGPLG GPLKFPNPCI LWLHADQADE
260 270 280 290 300
RLDKRVDDML AAGLLEELRD FHRRYNLKNV SEDSQDYQHG IFQSIGFKEF
310 320 330 340 350
HEYLTTEGKC TPETSNQLLK KGVEALKQVT KRYARKQNRW VRNRFLSRPG
360 370 380 390 400
PSVPPVYGLE VSDVSKWEEF VLEPALSIVQ SFIQGSKPTA TPVKIPYSET
410 420 430 440 450
ENKRSYHMCD LCDRIIIGDR EWAAHTKSKS HLHQLKKRRK LDLDAVSALG
460 470
SQSNSPDSEL ERKEGESSGQ RDQELKASV
Length:479
Mass (Da):53,667
Last modified:April 20, 2010 - v1
Checksum:i12C50FB9388C4FE4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07049850 Genomic DNA No translation available.
AABR07049851 Genomic DNA No translation available.
CH473968 Genomic DNA Translation: EDL80365.1
RefSeqiNP_001102146.1, NM_001108676.1
UniGeneiRn.74419

Genome annotation databases

EnsembliENSRNOT00000019587; ENSRNOP00000019587; ENSRNOG00000014274
GeneIDi362586
KEGGirno:362586
UCSCiRGD:1304781 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07049850 Genomic DNA No translation available.
AABR07049851 Genomic DNA No translation available.
CH473968 Genomic DNA Translation: EDL80365.1
RefSeqiNP_001102146.1, NM_001108676.1
UniGeneiRn.74419

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019587

Proteomic databases

PRIDEiD4A175

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000019587; ENSRNOP00000019587; ENSRNOG00000014274
GeneIDi362586
KEGGirno:362586
UCSCiRGD:1304781 rat

Organism-specific databases

CTDi54802
RGDi1304781 Trit1

Phylogenomic databases

eggNOGiKOG1384 Eukaryota
COG0324 LUCA
GeneTreeiENSGT00390000015214
KOiK00791
OMAiCQHHMIS
OrthoDBiEOG091G0VY8
TreeFamiTF315069

Gene expression databases

BgeeiENSRNOG00000014274 Expressed in 10 organ(s), highest expression level in colon

Family and domain databases

HAMAPiMF_00185 IPP_trans, 1 hit
InterProiView protein in InterPro
IPR039657 Dimethylallyltransferase
IPR030666 IPP_transferase_euk
IPR018022 IPT
IPR027417 P-loop_NTPase
IPR022755 Znf_C2H2_jaz
IPR036236 Znf_C2H2_sf
PANTHERiPTHR11088 PTHR11088, 1 hit
PfamiView protein in Pfam
PF01715 IPPT, 1 hit
PF12171 zf-C2H2_jaz, 1 hit
PIRSFiPIRSF039110 IPP_transferase, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF57667 SSF57667, 1 hit
TIGRFAMsiTIGR00174 miaA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD4A175_RAT
AccessioniPrimary (citable) accession number: D4A175
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 7, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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