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Entry version 77 (02 Jun 2021)
Sequence version 1 (20 Apr 2010)
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Protein
Submitted name:

SOGA family member 3

Gene

Soga3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
SOGA family member 3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Soga3Imported
Synonyms:NEWGENE_1307525Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Rat genome database

More...
RGDi
11479453, Soga3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei913 – 943HelicalSequence analysisAdd BLAST31

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

PhosphoproteinARBA annotation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
D4A0A1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
D4A0A1

PRoteomics IDEntifications database

More...
PRIDEi
D4A0A1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
D4A0A1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
D4A0A1

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
D4A0A1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000012324, Expressed in frontal cortex and 15 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
D4A0A1, RN

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
D4A0A1, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000016712

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
D4A0A1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 249DisorderedSequence analysisAdd BLAST249
Regioni266 – 292DisorderedSequence analysisAdd BLAST27
Regioni308 – 365DisorderedSequence analysisAdd BLAST58
Regioni493 – 521DisorderedSequence analysisAdd BLAST29
Regioni740 – 810DisorderedSequence analysisAdd BLAST71

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili382 – 416Sequence analysisAdd BLAST35
Coiled coili588 – 622Sequence analysisAdd BLAST35
Coiled coili632 – 680Sequence analysisAdd BLAST49
Coiled coili695 – 722Sequence analysisAdd BLAST28
Coiled coili812 – 832Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi66 – 90Polar residuesSequence analysisAdd BLAST25
Compositional biasi208 – 239Polar residuesSequence analysisAdd BLAST32
Compositional biasi316 – 344Polar residuesSequence analysisAdd BLAST29
Compositional biasi345 – 365Basic and acidic residuesSequence analysisAdd BLAST21
Compositional biasi744 – 786Basic and acidic residuesSequence analysisAdd BLAST43

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SOGA family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4787, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182982

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_013722_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
D4A0A1

Identification of Orthologs from Complete Genome Data

More...
OMAi
KSGGHES

Database of Orthologous Groups

More...
OrthoDBi
34629at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
D4A0A1

TreeFam database of animal gene trees

More...
TreeFami
TF331853

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027881, SOGA

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF11365, SOGA, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D4A0A1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQPPSGGAA PAATSASAAA AATEARMHPE GSSRKQQRAQ SPARPRDNSL
60 70 80 90 100
RQAAGAARSP LGVGPKLNSV RQQQLLQQQQ QGNKTTGRGA SGAGSRGYGG
110 120 130 140 150
GAEKAAPSLP KGAAPGAVQP APGAEGSPAA IPGAVSCRRS GLPVEPPQEI
160 170 180 190 200
ESGPSKVGEP PPLGGGGGGG EGGGAGGGPG DREGGAPQPP PPRGWRGKGV
210 220 230 240 250
RASQRGISGE GVSPSPPTAA TSRTPGPGSR NSGSGGTGGG SGGGGSYWKE
260 270 280 290 300
GCLQSELIQF HLKKERAAAA AAAAQMHTKN GGGGSRNSPV AGAPAICEPL
310 320 330 340 350
VVPSFSPMAA AAEGPQQSAE GSSSAGAMQA AAPPSTQPHS QQLQEQEDMQ
360 370 380 390 400
EEMEKLREEN ETLKNEIDEL RTEMDEMRDT FFEEDACQLQ EMRHELERAN
410 420 430 440 450
KNCRILQYRL RKAERKRLRY AQTGEIDGEL LRSLEQDLKV AKDVSVRLHH
460 470 480 490 500
ELENVEEKRT TTEDENEKLR QQLIEVEIAK QALQNELEKM KELSLKRRGS
510 520 530 540 550
KDLPKSEKKA QQTPTEDDNE DLKCQLQFVK EEAALMRKKM AKIDKEKDRF
560 570 580 590 600
EHELQKYRSF YGDLDSPLPK GEAGGPPSTR EAELKLRLRL VEEEANILGR
610 620 630 640 650
KIVELEVENR GLKAELDDLR GDDFNGSSNP LMREQSESLS ELRQHLQLVE
660 670 680 690 700
DETELLRRNV ADLEEQNKRI TAELNKYKYK SSGHDSSRHH DSAKTEALQE
710 720 730 740 750
ELKAARLQIN ELSGKVMQLQ YENRVLMSNM QRYDLASHLG IRGSPRDSDA
760 770 780 790 800
ESDAGKKESD DDSRPPHRKR EGPIGGESDS EEVRNIRSLT PTRSFYPTPG
810 820 830 840 850
PWPKSFSDRQ QMKDIRSEAE RLGKTIDRLI ADTSTIITEA RIYVANGDLF
860 870 880 890 900
GLMDEEDDGS RIREHELLYR INAQMKAFRK ELQTFIDRLE VPKSADDHGA
910 920 930 940
EEPISVSQMF QPIILLILIL VLFSSLSYTT IFKLVFLFTL FFVL
Length:944
Mass (Da):103,026
Last modified:April 20, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2C2C7E5D9B34C231
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AABR07000986 Genomic DNA No translation available.
AABR07000987 Genomic DNA No translation available.
AABR07000988 Genomic DNA No translation available.
AABR07000989 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_017443824.1, XM_017588335.1
XP_017443827.1, XM_017588338.1
XP_017445361.1, XM_017589872.1
XP_017445362.1, XM_017589873.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000016712; ENSRNOP00000016712; ENSRNOG00000012324

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
108349256

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:108349256

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07000986 Genomic DNA No translation available.
AABR07000987 Genomic DNA No translation available.
AABR07000988 Genomic DNA No translation available.
AABR07000989 Genomic DNA No translation available.
RefSeqiXP_017443824.1, XM_017588335.1
XP_017443827.1, XM_017588338.1
XP_017445361.1, XM_017589872.1
XP_017445362.1, XM_017589873.1

3D structure databases

SMRiD4A0A1
ModBaseiSearch...

Protein-protein interaction databases

IntActiD4A0A1, 1 interactor
STRINGi10116.ENSRNOP00000016712

PTM databases

iPTMnetiD4A0A1
PhosphoSitePlusiD4A0A1
SwissPalmiD4A0A1

Proteomic databases

jPOSTiD4A0A1
PaxDbiD4A0A1
PRIDEiD4A0A1

Genome annotation databases

EnsembliENSRNOT00000016712; ENSRNOP00000016712; ENSRNOG00000012324
GeneIDi108349256
KEGGirno:108349256

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
387104
RGDi11479453, Soga3

Phylogenomic databases

eggNOGiKOG4787, Eukaryota
GeneTreeiENSGT00950000182982
HOGENOMiCLU_013722_0_0_1
InParanoidiD4A0A1
OMAiKSGGHES
OrthoDBi34629at2759
PhylomeDBiD4A0A1
TreeFamiTF331853

Gene expression databases

BgeeiENSRNOG00000012324, Expressed in frontal cortex and 15 other tissues
GenevisibleiD4A0A1, RN

Family and domain databases

InterProiView protein in InterPro
IPR027881, SOGA
PfamiView protein in Pfam
PF11365, SOGA, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD4A0A1_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D4A0A1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: June 2, 2021
This is version 77 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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